ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1RUW-4.PDB
Scoring matrix: MYO3_1RUW-4_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.74
Foldx random average score for Saccharomyces cerevisiae: 23.943

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1448400
Proteins after disorder filtering: 4510
 Total fragments: 98690
Proteins after pattern filtering: 2286
 Total fragments: 20684
Proteins after MINT filtering: 26
 Total fragments: 1052

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.74

0.29

0.00

Best peptides

FRPRRFRPAW

0.00

-3.26

-3.55

         
Interactors      
P39113

HRGPRRPQKN

13.79

-5.11

-5.41

PLGAPPPPPH

14.40

-7.04

-7.34

ASHRGPRRPQ

15.39

-3.17

-3.46

P36150

PIVVNPSSPS

17.06

-4.50

-4.79

NPIVVNPSSP

21.67

-2.18

-2.48

P38822

DRGPAPEVPP

13.84

-3.89

-4.19

APEVPPPRRS

19.81

-4.90

-5.20

PAPEVPPPRR

20.11

-5.21

-5.50

P40341

SRNIPPPPPP

12.39

-4.90

-5.20

NIPPPPPPPP

13.75

-5.23

-5.53

PPPPPPPPPK

15.64

-7.78

-8.08

Q08912

PKGPPPPPPP

12.02

-6.25

-6.54

DHPKGPPPPP

13.87

-3.68

-3.98

HPKGPPPPPP

14.51

-7.17

-7.46

P17555

SKSGPPPRPK

12.98

-5.27

-5.56

PRPKKPSTLK

14.59

-2.88

-3.17

PAPPPPPPAP

15.76

-4.36

-4.66

P25604

LKPPLPPPPP

10.23

-5.91

-6.21

PLPPKPKSPH

13.86

-5.93

-6.22

PPPPPPQPAS

14.44

-4.89

-5.18

P47068

PLPRAPPVPP

11.20

-6.66

-6.96

HPVPSAPSAP

15.06

-4.93

-5.22

DKVPPHPVPS

15.07

-5.36

-5.66

P04050

LPVPPPPVRP

17.60

-5.32

-5.62

PVPPPPVRPS

17.87

-3.90

-4.20

PPVRPSISFN

18.35

-2.11

-2.40

P40450

KLPQLPPPPP

13.35

-6.41

-6.71

QLPPPPPPPP

13.71

-5.36

-5.66

LPPPPPPPPP

14.74

-6.99

-7.29

P40453

LRKRPPPPPP

6.27

-7.23

-7.53

RKRPPPPPPV

12.98

-4.44

-4.74

RLRKRPPPPP

13.79

-6.37

-6.67

P41832

PKGETPPPPP

12.35

-5.67

-5.96

PPPPPPVPAK

13.60

-6.01

-6.30

PPPPPPPMAL

14.85

-6.47

-6.76

Q12342

RKAKAPPPPP

11.84

-5.22

-5.51

AKAPPPPPPP

12.02

-5.02

-5.31

APPPPPPPPP

15.87

-6.10

-6.39

P38237

DLNDPFVPPP

13.85

-4.76

-5.05

FVPPPNVPKK

18.81

-3.27

-3.56

PFVPPPNVPK

19.37

-4.20

-4.50

P53094

FKSSAFPQSP

12.99

-3.44

-3.73

TREPNEPPPP

14.61

-3.94

-4.24

PQTREPNEPP

14.86

-3.60

-3.90

Q01389

PKREAPKPPA

13.45

-4.32

-4.62

APKREAPKPP

14.68

-5.42

-5.71

PKPPANTSPQ

15.31

-2.57

-2.86

P40021

TKNTGPPPPL

13.60

-4.54

-4.84

NSPPLPPPAR

15.80

-3.93

-4.23

NTGPPPPLPP

17.67

-3.68

-3.98

Q04439

PKEPMFEAAY

10.10

-3.67

-3.96

ARPSPPTAAT

11.27

-2.37

-2.67

KKPAPPPPGM

12.17

-4.27

-4.56

Q12446

NRNNRPVPPP

10.68

-5.10

-5.39

NRPVPPPPPM

10.78

-5.43

-5.72

RRGPAPPPPP

11.33

-5.18

-5.47

Q01560

HHQPPEPQPY

15.31

-6.66

-6.96

EPQPYYPPPP

15.58

-4.39

-4.68

HQPPEPQPYY

15.87

-2.22

-2.52

P00950

DVPPPPIDAS

15.67

-3.60

-3.90

RSFDVPPPPI

18.48

-4.57

-4.87

RRSFDVPPPP

20.87

-2.05

-2.34

P33334

KMPTRFPPAV

10.97

-4.81

-5.10

FLPPPPPPPS

13.96

-7.10

-7.39

ALPPPPPPPP

14.34

-6.33

-6.63

P40523

YMHNSPRNPD

15.02

-5.62

-5.92

PLAPPPHGPF

15.29

-6.37

-6.67

VPVGVPPLAP

17.29

-4.25

-4.54

Q08989

PKGPPPPPPP

12.02

-6.25

-6.54

DHPKGPPPPP

13.87

-3.68

-3.98

HPKGPPPPPP

14.51

-7.17

-7.46

P37370

PKPRPFQNKT

10.30

-2.43

-2.73

EKPPSPPVAA

11.82

-2.93

-3.23

THVSNPPQAP

12.91

-3.02

-3.31

P39743

PNATIPEDNP

20.54

-1.87

-2.17

PAYSNPLTSP

23.72

-0.75

-1.04

 


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