ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1RUW-26.PDB
Scoring matrix: MYO3_1RUW-26_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 13.39
Foldx random average score for Saccharomyces cerevisiae: 15.363

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 1412912
Proteins after disorder filtering: 4590
 Total fragments: 76397
Proteins after pattern filtering: 2142
 Total fragments: 9787
Proteins after MINT filtering: 25
 Total fragments: 366

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

13.39

3.21

0.00

Best peptides

DPADRRPPK

0.00

-1.63

-4.84

         
Interactors      
P39113

GPRRPQKNR

9.25

-2.51

-5.72

ASHRGPRRP

12.05

-0.75

-3.96

SHRGPRRPQ

12.17

-4.78

-7.99

P36150

PIVVNPSSP

14.63

-1.50

-4.71

IVVNPSSPS

15.01

-1.25

-4.46

P38822

APEVPPPRR

10.01

-2.87

-6.08

PAPEVPPPR

11.91

-3.61

-6.82

DTPTTTPGS

12.58

-2.43

-5.64

P40341

NSRNIPPPP

10.40

-2.47

-5.68

NDPSNPVSK

12.24

-2.05

-5.26

PLNDPSNPV

15.12

0.98

-2.23

Q08912

HPKGPPPPP

12.35

-2.33

-5.54

DHPKGPPPP

12.98

-5.20

-8.41

YTPSWGPSP

14.22

-1.31

-4.52

P17555

ATAAPAPPP

10.61

-2.09

-5.30

PPPRPKKPS

11.61

-2.83

-6.04

AAPAPPPPP

12.04

-2.87

-6.08

P25604

PKPKSPHLK

10.96

-2.37

-5.58

TPPLPPKPK

11.96

-4.13

-7.34

LPPKPKSPH

12.69

-2.81

-6.02

P47068

PSSNPFFRK

9.82

-0.93

-4.14

EPISPETKK

10.24

-2.87

-6.08

DPSSNPFFR

10.37

-2.55

-5.76

P04050

PPVRPSISF

11.69

-3.12

-6.33

CLPVPPPPV

12.46

-2.97

-6.18

TSPNYSPTS

13.84

-1.33

-4.54

P40450

CGAVPPPPP

9.33

-2.83

-6.04

CIAAPAPPP

10.79

-2.14

-5.35

PKLFPRLSS

11.33

-2.59

-5.80

P40453

LRKRPPPPP

10.68

-2.77

-5.98

PPPVSMPTT

11.15

-3.69

-6.90

EPPSWKPPD

11.27

-3.21

-6.42

P41832

DSPAPPPPP

10.58

-4.00

-7.21

KGETPPPPP

12.53

-0.96

-4.17

IPPAPPMMP

13.18

-2.64

-5.85

Q12342

RKAKAPPPP

10.86

-2.97

-6.18

KAKAPPPPP

11.19

-2.44

-5.65

ETPSTPSDG

14.51

-0.89

-4.10

P38237

DPFVPPPNV

11.85

-1.84

-5.05

NDPFVPPPN

12.13

-2.26

-5.47

PDLNDPFVP

13.99

-1.77

-4.98

P53094

DDEDPVSPK

8.81

-1.45

-4.66

FPQSPIRAY

10.17

-2.06

-5.27

REPNEPPPP

11.01

-2.42

-5.63

Q01389

GIASPTSPK

8.32

-1.21

-4.42

KSASPPASP

10.73

-0.40

-3.61

PPASPSYPS

11.21

-1.03

-4.24

P40021

PPPLPPPLF

12.06

-3.43

-6.64

HPPNHPHSQ

12.21

-2.05

-5.26

KNTGPPPPL

12.76

-2.56

-5.77

Q04439

RQANIPPPP

8.52

-2.23

-5.44

KKPAPPPPG

11.12

-3.06

-6.27

NIPTPPQNR

12.07

-3.77

-6.98

Q12446

PPASPEVRK

9.14

-1.31

-4.52

TSAAPPPPP

9.65

-2.63

-5.84

QPQSNPFPF

10.09

-1.57

-4.78

Q01560

PQPYYPPPP

11.87

-2.83

-6.04

PPPSNAPIY

12.04

-2.78

-5.99

QPYYPPPPP

12.18

-2.11

-5.32

P00950

RSFDVPPPP

10.82

-1.58

-4.79

P33334

PSLNPIPHF

8.93

-3.73

-6.94

PTRFPPAVF

9.99

-0.46

-3.67

DLALPPPPP

10.64

-3.31

-6.52

P40523

PVPVGVPPL

12.31

-2.71

-5.92

APPGTVPNM

12.44

-3.27

-6.48

ENITPLPTP

12.54

-3.37

-6.58

Q08989

HPKGPPPPP

12.35

-2.33

-5.54

DHPKGPPPP

12.98

-5.20

-8.41

TNGDHPKGP

14.78

-1.51

-4.72

P37370

ISPSINPPK

9.20

-2.18

-5.39

PKPRPFQNK

9.65

-1.55

-4.76

VKATPVPPT

10.52

-1.46

-4.67

 


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