ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1RUW-21.PDB
Scoring matrix: MYO3_1RUW-21_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 22.61
Foldx random average score for Saccharomyces cerevisiae: 20.408

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1718614
Proteins after disorder filtering: 4359
 Total fragments: 60214
Proteins after pattern filtering: 1643
 Total fragments: 3982
Proteins after MINT filtering: 22
 Total fragments: 133

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

22.61

-0.04

0.00

Best peptides

EEKMGRPRMR

0.00

-4.71

-4.67

         
Interactors      
P39113

PRRPQKNRYN

14.48

-2.64

-2.60

HRGPRRPQKN

15.39

-2.84

-2.80

RGPRRPQKNR

15.44

-2.38

-2.34

P25604

PPKPKSPHLK

12.31

-4.02

-3.98

PPKPNTQLQQ

17.80

-2.81

-2.77

PPQPASNALD

19.21

-4.07

-4.03

P53094

LNVPLPPQTR

14.81

-3.52

-3.48

SAFPQSPIRA

17.53

-3.17

-3.13

AFPQSPIRAY

18.23

-2.69

-2.65

P40341

LNDPSNPVSK

17.20

-2.46

-2.42

P17555

PKKPSTLKTK

14.47

-3.30

-3.26

PRPKKPSTLK

15.34

-3.71

-3.67

PPRPKKPSTL

17.35

-2.65

-2.61

Q08912

PPPPDEKDRG

19.49

-2.60

-2.56

Q12342

LETPSTPSDG

18.27

-1.12

-1.08

P47068

PEPISPETKK

13.07

-3.56

-3.52

VDPSSNPFFR

16.28

-0.79

-0.75

LPEPISPETK

16.61

-1.73

-1.69

P04050

GEAPTSPGFG

16.66

-3.23

-3.19

GFSPTSPTYS

16.66

-2.83

-2.79

GYSPGSPAYS

17.60

-2.79

-2.75

P40450

PPLPDLFKTK

13.90

-3.56

-3.52

SSPKLFPRLS

15.45

-3.17

-3.13

APPPLPDLFK

17.91

-3.91

-3.87

P40453

PDLPIRLRKR

8.79

-3.69

-3.65

KPPDLPIRLR

14.53

-5.90

-5.86

TKVPEPPSWK

18.93

-3.90

-3.86

P41832

PPPPMALFGK

19.94

-1.81

-1.77

P38237

VPPPNVPKKD

17.25

-3.98

-3.94

PSKPENTVNL

18.48

-1.19

-1.15

FQIPSKPENT

18.88

-0.30

-0.26

Q01389

RSKPLPPQLL

16.02

-3.12

-3.08

IASPTSPKSL

16.62

-2.02

-1.98

REAPKPPANT

16.68

-1.75

-1.71

P40021

DFLPSTPSQM

16.32

-3.38

-3.34

SHPPNHPHSQ

19.50

-1.30

-1.26

VISPNLPTTI

19.71

-2.07

-2.03

Q04439

SSKPKEPMFE

14.77

-2.75

-2.71

NNIPTPPQNR

15.59

-2.96

-2.92

PPPPGMQNKA

19.38

-3.81

-3.77

Q12446

RPLPQLPNRN

16.45

-3.89

-3.85

FPFPVPQQQF

17.08

-2.73

-2.69

PEIPSTQSAT

17.35

-0.82

-0.78

Q01560

PQEPQVPQES

18.41

-1.46

-1.42

PPPPGEHMHG

18.93

-3.63

-3.59

QEPPAPQEQN

19.83

-0.24

-0.20

P33334

NAIPGGPKFE

14.57

-3.43

-3.39

MPTRFPPAVF

18.35

-2.77

-2.73

LDNPMVPSSV

19.52

-0.97

-0.93

P40523

PHGPFSTSML

16.21

-2.59

-2.55

HNSPRNPDTG

17.76

-1.14

-1.10

PPGTVPNMQM

18.51

-2.99

-2.95

P38822

APEVPPPRRS

19.77

-4.84

-4.80

P37370

QNRPHMPSVR

14.05

-2.97

-2.93

ASAPKVPQNR

14.90

-2.17

-2.13

MPKPRPFQNK

15.32

-2.17

-2.13

 


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