ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: MYO3_1R6S-11.PDB
Scoring matrix: MYO3_1R6S-11_mat
Uniprot code: P36006
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.16
Foldx random average score for Saccharomyces cerevisiae: 9.139

Available information for P36006 in MINT (Nov 2008):
Nš of interacting proteins: 43
 Proteins belonging to other specie: 0
Nš of interactions described: 74
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1442480
Proteins after disorder filtering: 4684
 Total fragments: 75637
Proteins after pattern filtering: 2146
 Total fragments: 9927
Proteins after MINT filtering: 25
 Total fragments: 505

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.16

0.91

0.00

Best peptides

RMWIPPR

0.00

-4.00

-4.91

         
Interactors      
P39113

RGPRRPQ

5.08

-3.95

-4.86

PLGAPPP

6.96

-2.81

-3.71

LGAPPPP

7.36

-3.11

-4.01

P25604

PHLKPPL

6.21

-2.57

-3.47

PLPPPPP

6.23

-4.29

-5.20

KPPLPPP

6.30

-4.82

-5.73

P38822

PEVPPPR

5.44

-4.37

-5.28

APEVPPP

7.54

-3.23

-4.13

PTTTPGS

8.93

-2.04

-2.95

P40341

RNIPPPP

5.19

-5.65

-6.56

NIPPPPP

6.05

-2.14

-3.04

PPPPPPK

7.59

-3.33

-4.24

Q08912

KGPPPPP

6.52

-3.65

-4.55

PKGPPPP

7.42

-3.35

-4.25

PSWGPSP

8.38

-1.79

-2.70

P17555

PPPRPKK

6.96

-2.97

-3.88

RPKKPST

6.97

-4.71

-5.62

PAPPPPP

6.99

-3.52

-4.42

Q12342

KAPPPPP

5.95

-4.22

-5.13

AKAPPPP

7.25

-3.64

-4.54

APPPPPP

8.70

-3.11

-4.01

P47068

PHPVPSA

6.45

-1.53

-2.44

TAPPLPR

6.78

-0.86

-1.77

PRAPPVP

6.99

-2.76

-3.67

P04050

CLPVPPP

4.87

-4.40

-5.31

PVPPPPV

7.73

-2.72

-3.63

PAYSPKQ

7.84

-1.88

-2.79

P40450

QLPPPPP

5.27

-5.14

-6.04

KLPQLPP

5.62

-3.11

-4.01

PQLPPPP

6.78

-3.64

-4.54

P40453

KRPPPPP

4.91

-4.98

-5.89

RKRPPPP

4.91

-6.11

-7.02

PPPLPPK

6.23

-3.93

-4.84

P41832

PPPVPAK

6.88

-3.13

-4.04

PAPPPPP

6.99

-3.52

-4.42

QPPPPPP

7.74

-3.63

-4.54

P38237

PPNVPKK

7.45

-3.03

-3.93

PFVPPPN

7.70

-2.57

-3.47

QIPSKPE

7.75

-0.94

-1.85

P53094

REPNEPP

5.12

-3.64

-4.54

NVPLPPQ

5.18

-3.59

-4.50

PLKLPPL

5.29

-4.70

-5.61

Q01389

REAPKPP

5.91

-5.37

-6.28

RSKPLPP

6.51

-3.71

-4.62

SKPLPPQ

6.70

-4.77

-5.67

P40021

PLPPPAR

5.32

-3.47

-4.38

PLPPPLF

5.79

-3.06

-3.96

PPPLPPP

7.35

-4.37

-5.28

Q04439

NIPTPPQ

5.38

-3.40

-4.30

KKPAPPP

6.00

-3.95

-4.86

NIPPPPP

6.05

-2.14

-3.04

Q12446

RLPAPPP

4.21

-5.90

-6.81

NRPVPPP

4.41

-3.26

-4.17

PFPVPQQ

5.17

-2.84

-3.75

Q01560

PEPQPYY

5.42

-4.49

-5.40

PQPYYPP

5.85

-3.11

-4.01

QPYYPPP

6.74

-3.55

-4.46

P00950

DVPPPPI

8.14

-2.04

-2.95

FDVPPPP

8.36

-2.31

-3.21

P33334

KMPTRFP

6.22

-3.37

-4.28

ALPPPPP

6.23

-4.07

-4.98

TLPPPPP

6.40

-3.03

-3.93

P40523

ITPLPTP

6.20

-3.18

-4.09

PLAPPPH

6.24

-3.50

-4.41

PVGVPPL

6.60

-2.98

-3.88

Q08989

KGPPPPP

6.52

-3.65

-4.55

PKGPPPP

7.42

-3.35

-4.25

PPPPPPP

8.70

-3.38

-4.29

P37370

QMPKPRP

4.17

-4.95

-5.86

LAPLPPP

5.04

-4.99

-5.90

PKPRPFQ

5.76

-3.75

-4.66

P39743

PLTSPVA

8.57

-1.19

-2.09

 


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