ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-7.PDB
Scoring matrix: LSB3_2A08-7_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.45
Foldx random average score for Saccharomyces cerevisiae: 9.858

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1412883
Proteins after disorder filtering: 4566
 Total fragments: 57216
Proteins after pattern filtering: 1959
 Total fragments: 7401
Proteins after MINT filtering: 65
 Total fragments: 468


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.45

-2.21

0.00
Best peptides

MPPRVFRR

0.00

-7.39

-5.18
         
Interactors      
P38140

QPDLPPRK

8.26

-6.71

-4.50

MNIQPDLP

9.13

-3.89

-1.68

PDLPPRKI

9.77

-5.51

-3.30
Q06604

KGPRMPSR

4.54

-5.16

-2.95

PAPPVSRS

5.56

-5.44

-3.23

LLPTRPNK

6.60

-5.25

-3.04
P24814

PPDIHPNL

7.59

-2.47

-0.26

LHPPDIHP

9.08

-4.02

-1.81
P25604

PLPPKPKS

6.83

-4.64

-2.43

PPKPKSPH

7.96

-4.28

-2.07

PKPKSPHL

8.20

-3.57

-1.36
P40956

PPLPRRRA

5.51

-5.27

-3.06

WNPKNVPF

7.52

-3.56

-1.35

NPKNVPFP

7.83

-5.22

-3.01
P25623

LPKTVPIS

5.80

-5.69

-3.48

KPLPVEPA

6.59

-4.28

-2.07

PLQPQSKT

8.08

-4.44

-2.23
Q04322

PPTLPPRR

7.91

-7.02

-4.81

APLDRPQL

8.35

-2.31

-0.10

TSPPLPPR

8.67

-4.32

-2.11
P38266

KPPVVPKK

3.11

-6.12

-3.91

VPPVVPKK

3.20

-6.65

-4.44

MPPPKPFR

3.38

-6.47

-4.26
P47043

KPPQLPPK

7.10

-4.40

-2.19

KNKPNPPP

8.93

-4.02

-1.81
P15891

TPEKKPKE

6.58

-4.77

-2.56

APPPPPRR

6.93

-6.49

-4.28

RATPEKKP

7.76

-3.64

-1.43
P40341

PPPPKPPL

7.68

-4.39

-2.18

PPPKPPLN

7.78

-6.54

-4.33

KPPLNDPS

8.85

-3.62

-1.41
Q12134

QPVPSPMN

8.29

-4.41

-2.20

THQPVPSP

9.46

-3.31

-1.10
P40494

RPPPKPLH

4.17

-6.12

-3.91

PPNMMPVT

7.08

-4.92

-2.71

RPPRPPPK

7.26

-6.55

-4.34
Q12200

LPCPVPRS

4.58

-6.82

-4.61

CPHLKPLK

5.35

-5.45

-3.24

PSDPCPLG

7.43

-4.85

-2.64
Q12344

PLPPRQNV

7.87

-4.27

-2.06

TSPKLPPR

7.94

-5.69

-3.48

SSPPLPPR

8.84

-3.98

-1.77
P53238

KPAGRPIP

7.37

-1.86

0.35

PPAPTHYN

8.66

-3.62

-1.41

IPPAPTHY

9.46

-4.54

-2.33
P32660

TDPNRPKV

6.78

-3.73

-1.52

HAPMSPFE

8.05

-3.22

-1.01

YDPTDPNR

8.08

-3.42

-1.21
P33400

PPLPVGIS

6.65

-4.59

-2.38

ILPPLPVG

8.45

-3.17

-0.96

SPQILPPL

9.12

-5.49

-3.28
P53901

LPPIPTRD

7.10

-6.87

-4.66

MRPIPPLP

7.25

-7.18

-4.97

KLPPLPTT

8.75

-4.86

-2.65
P38739

SPFHDPIL

8.19

-4.16

-1.95

ASPFHDPI

9.21

-0.20

2.01

PNDPSTLA

9.25

-3.65

-1.44
Q04749

PLPVLPRR

5.80

-7.70

-5.49

NPVFNPRK

6.44

-6.06

-3.85

FNPRKPTL

6.60

-4.48

-2.27
P04051

RSLPHFPK

6.86

-1.16

1.05

VNPAMLPG

8.10

-4.32

-2.11

PHFPKNSK

9.11

-2.96

-0.75
P40325

RPPPRPQQ

5.00

-4.89

-2.68

RPHQRPST

5.95

-2.52

-0.31

RPSTMPAT

7.52

-3.86

-1.65
P47129

LPNRKPNP

7.36

-5.65

-3.44

KPNPPPNR

8.35

-5.14

-2.93

PPLLPPRN

8.88

-7.31

-5.10
P40453

PPPPVSMP

6.72

-5.65

-3.44

KPPDLPIR

6.84

-4.38

-2.17

IPPPLPPK

7.59

-4.57

-2.36
P40095

LPPPRSPN

6.59

-4.57

-2.36

RSPNRPTL

7.06

-2.68

-0.47

PPPRSPNR

7.12

-4.81

-2.60
Q12168

IPPPVPNR

4.58

-5.73

-3.52

PYFPQFRS

6.35

-4.59

-2.38

VQHPVPKP

6.83

-5.65

-3.44
P36125

PAGPQGQR

8.27

-3.07

-0.86
P36123

KTPPRPKT

5.80

-4.66

-2.45

LFPPDHFP

8.45

-4.71

-2.50

PDHFPSRS

8.71

-5.29

-3.08
Q08412

VPPQLPTR

7.04

-5.88

-3.67

PLPPEPLD

7.24

-4.82

-2.61

LPTQPVRK

7.55

-6.40

-4.19
Q06697

GGPRKDPI

8.54

-3.76

-1.55
Q06409

KPRKTPRP

6.04

-6.35

-4.14

RKTPRPPF

6.04

-3.55

-1.34

GKPRKTPR

7.45

-4.05

-1.84
P32634

PLPPVPKA

5.55

-5.69

-3.48

PLPPQEKI

7.22

-4.59

-2.38

NLPIVPNP

7.29

-5.17

-2.96
Q06833

RRPSQPLN

6.77

-3.59

-1.38

RPVPRRPS

6.82

-3.39

-1.18

ENFPVPPS

7.56

-4.58

-2.37
P53118

VENPHDLP

9.62

-2.53

-0.32

ENPHDLPS

9.83

-2.55

-0.34
Q12199

PNNPQCLH

7.20

-4.57

-2.36

APATPPRH

8.64

-5.88

-3.67

TPSVQPTA

8.85

-3.02

-0.81
P19158

MTPVSPLG

7.63

-3.92

-1.71

SMTPVSPL

8.79

-3.72

-1.51
P38870

TTPERPKR

7.13

-3.42

-1.21

TPERPKRK

7.41

-7.41

-5.20

PERPKRKS

9.02

-5.43

-3.22
P43638

PKLPSAFR

8.26

-4.56

-2.35

PPHPDAPK

8.82

-4.88

-2.67

PHPDAPKL

8.84

-4.33

-2.12
P53933

NDLPMELP

7.90

-5.27

-3.06

APPPLPNR

7.99

-5.60

-3.39

RPPPPPIP

8.43

-4.48

-2.27
P50101

VFPGSPID

9.50

-2.77

-0.56
P40020

MSLPVTPV

6.29

-4.31

-2.10

PSIPVEHS

7.41

-3.73

-1.52

VLPPLPFP

7.67

-7.17

-4.96
P38238

LDPVQSPT

7.83

-3.37

-1.16

QSPTNPPY

9.05

-3.23

-1.02
P00175

RFLPNHPG

9.06

-3.16

-0.95

CPPYAPGE

9.41

-2.88

-0.67
Q08229

LPTPVQPG

7.75

-4.54

-2.33

NPTIPPRS

7.99

-6.28

-4.07

RPLPSTPN

9.22

-2.71

-0.50
P38930

FPDMVPKH

3.90

-6.40

-4.19

AFPDMVPK

9.30

-3.08

-0.87
Q12446

FPFPVPQQ

6.13

-5.19

-2.98

PPPRRGPA

6.32

-5.40

-3.19

VPPPPPMR

6.52

-7.47

-5.26
P32855

NAPTLPKR

8.03

-4.88

-2.67

APTLPKRK

8.88

-5.84

-3.63
Q12211

RPKSGPRL

7.31

-4.61

-2.40

KRPKSGPR

7.66

-3.82

-1.61

NPLPKEPR

8.17

-3.80

-1.59
Q06116

SPELVPRS

6.09

-6.12

-3.91

HSEPVEPF

7.65

-3.26

-1.05

PFYPVTSE

8.91

-2.91

-0.70
P33336

CDPEDYPT

9.66

-2.57

-0.36
P50942

RPCPPIRR

6.80

-6.76

-4.55

PPPPTSRH

6.88

-5.54

-3.33

VPRPCPPI

7.05

-5.77

-3.56
Q06266

QFPSSPYR

8.41

-3.15

-0.94

VDPYSPPN

8.59

-3.36

-1.15

PSSPAFPG

9.20

-3.09

-0.88
Q00916

LFKPRPPL

6.58

-4.94

-2.73

FKPRPPLS

7.43

-5.61

-3.40

PRPPLSYK

7.91

-5.48

-3.27
P07269

SGPQRPKR

4.82

-4.02

-1.81

PNTPDFLK

6.95

-4.46

-2.25

DSGPQRPK

9.46

-2.56

-0.35
P40563

APPPVPKK

4.69

-5.43

-3.22

VTPKVPER

5.86

-5.11

-2.90

PSERPKRR

6.76

-7.06

-4.85
P10566

PAIPMDLP

8.14

-4.27

-2.06

RPIPAIPM

8.58

-3.67

-1.46

IPAIPMDL

9.77

-2.17

0.04
P38289

EDPENPSF

9.34

-2.02

0.19
P47030

AFPPEPSM

9.18

-2.11

0.10

FPPEPSMS

9.77

-5.12

-2.91
P32790

LPPIKPPR

5.11

-6.21

-4.00

IKPPRPTS

6.84

-4.18

-1.97

PPPAMPAR

7.41

-4.48

-2.27
P32863

LPDRPPNG

9.05

-6.04

-3.83
P32862

VPSTPSRS

8.63

-5.18

-2.97

YRPPNPPA

8.86

-3.48

-1.27

MNPSNSPN

9.07

-2.67

-0.46
P31374

ISPERPSF

6.89

-2.15

0.06

PGTPVFPN

7.31

-3.61

-1.40

SPERPSFR

7.92

-6.10

-3.89
P53169

MPTLPPRP

8.18

-6.21

-4.00

IMPTLPPR

8.48

-5.50

-3.29

SVPIMPTL

8.66

-4.64

-2.43
P53955

QNDPRSPL

7.88

-2.94

-0.73

RNPIPYPI

8.84

-4.47

-2.26

 


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