ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-29.PDB
Scoring matrix: LSB3_2A08-29_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.03
Foldx random average score for Saccharomyces cerevisiae: 14.980

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1369521
Proteins after disorder filtering: 4062
 Total fragments: 47398
Proteins after pattern filtering: 1958
 Total fragments: 10626
Proteins after MINT filtering: 67
 Total fragments: 696


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.03

-1.06

0.00
Best peptides

DRPPIFRRRY

0.00

-11.10

-10.04
         
Interactors      
P38140

IQPDLPPRKI

8.39

-12.72

-11.66

QPDLPPRKIM

11.73

-8.67

-7.61

PMNIQPDLPP

12.15

-7.99

-6.93
Q06604

SPPPLPTRRD

6.71

-12.80

-11.74

EKPLLPTRPN

7.38

-13.60

-12.54

TPPSPPAKRI

8.50

-9.24

-8.18
P09119

TPTTSPVKKS

13.66

-6.53

-5.47

LTPTTSPVKK

14.26

-6.88

-5.82

PTTSPVKKSY

14.30

-5.65

-4.59
P24814

NNSTRPQMPS

11.63

-7.78

-6.72

NNNSTRPQMP

12.25

-6.10

-5.04

RLHPPDIHPN

13.09

-8.30

-7.24
P25604

NTPPLPPKPK

8.15

-11.83

-10.77

QAPSLPPKPN

9.76

-10.82

-9.76

PLPPKPKSPH

10.59

-8.86

-7.80
P40956

STPPLPRRRA

6.00

-14.05

-12.99

TSTPPLPRRR

8.48

-9.63

-8.57

TPPLPRRRAT

10.86

-9.35

-8.29
P25623

SQPPLQPQSK

12.14

-8.18

-7.12

PPLQPQSKTK

12.67

-6.15

-5.09

DTPPLPPHAT

12.73

-12.05

-10.99
Q04322

TPPTLPPRRI

6.68

-12.88

-11.82

TSPPLPPRAD

9.55

-11.58

-10.52

STPPTLPPRR

10.15

-8.39

-7.33
P38266

QPPPKPFRRS

5.44

-12.65

-11.59

GQPPVPVRMQ

6.84

-13.16

-12.10

FLPPPKPFRH

7.41

-10.12

-9.06
P47043

KPPQLPPKCS

10.59

-10.59

-9.53

SKPPQLPPKC

11.59

-6.85

-5.79

HLESKPPQLP

12.04

-9.08

-8.02
P15891

AAPPPPPRRA

7.24

-11.45

-10.39

RRATPEKKPK

8.94

-6.94

-5.88

AQPPLPSRNV

9.10

-12.04

-10.98
P40341

PPPPPPPKPP

10.27

-10.37

-9.31

PPPPKPPLND

12.00

-9.05

-7.99

PPPPPPPPPK

13.39

-8.20

-7.14
Q12134

HQPVPSPMNS

13.89

-5.58

-4.52

THQPVPSPMN

14.14

-6.34

-5.28
P40494

KDKSRPPRPP

8.35

-12.49

-11.43

RPPRPPPKPL

9.80

-9.82

-8.76

SRPPRPPPKP

11.19

-10.99

-9.93
Q12200

CPPSFPSRRC

7.02

-11.95

-10.89

ELPCPVPRSF

9.92

-10.42

-9.36

NELPCPVPRS

10.30

-7.74

-6.68
Q12344

SSPPLPPRQN

8.91

-11.61

-10.55

TSPKLPPRGK

9.52

-12.03

-10.97

PKLPPRGKQR

10.08

-9.79

-8.73
P53238

QKPAGRPIPP

13.33

-6.07

-5.01

PIPPAPTHYN

13.45

-9.55

-8.49

AGRPIPPAPT

13.78

-6.72

-5.66
P32660

YDPTDPNRPK

8.84

-11.00

-9.94

PTDPNRPKVT

11.46

-7.72

-6.66

GYDPTDPNRP

13.04

-5.99

-4.93
P33400

TSPQILPPLP

13.22

-7.76

-6.70

ILPPLPVGIS

13.60

-8.74

-7.68

SPQILPPLPV

13.62

-8.20

-7.14
P38739

SPFHDPILPR

13.53

-6.74

-5.68

ASPFHDPILP

13.69

-6.41

-5.35

TLASPFHDPI

14.83

-2.59

-1.53
Q04749

SPLPVLPRRI

5.34

-12.44

-11.38

PLPVLPRRIS

7.65

-13.43

-12.37

TNPVFNPRKP

9.45

-9.66

-8.60
P04051

RSLPHFPKNS

8.70

-7.34

-6.28

QDRSLPHFPK

11.40

-7.67

-6.61

PHFPKNSKTP

11.78

-7.13

-6.07
P43603

GRFTAPTSPS

14.44

-5.45

-4.39
P40325

SQPPRPPRPA

5.96

-13.20

-12.14

SQPRPPPRPQ

8.30

-12.49

-11.43

SLPWTYPPRF

8.99

-7.27

-6.21
P47129

INNTLPNRKP

9.91

-9.99

-8.93

GPPLLPPRNT

10.27

-12.35

-11.29

KPNPPPNRSQ

11.63

-8.81

-7.75
P40453

PDLPIRLRKR

6.89

-11.45

-10.39

KPPDLPIRLR

8.91

-13.28

-12.22

WKPPDLPIRL

9.28

-9.23

-8.17
P40095

PPPRSPNRPT

9.92

-11.33

-10.27

RIPVLPPPRS

11.00

-8.83

-7.77

NRIPVLPPPR

11.71

-6.93

-5.87
Q12168

IPPPVPNRPG

7.98

-11.90

-10.84

DDPYFPQFRS

8.63

-10.85

-9.79

GPPPLPPRAN

9.73

-12.34

-11.28
P36125

PAGPQGQRRR

10.12

-7.74

-6.68

LPAGPQGQRR

13.59

-5.75

-4.69
P32793

SLGHGPTHPS

14.71

-8.42

-7.36
P40528

PLPYPIAQVG

12.95

-7.79

-6.73

SLNDIPITPS

12.96

-7.40

-6.34

DIPITPSHDN

13.53

-8.94

-7.88
P36123

TTPKTPPRPK

7.74

-12.99

-11.93

FPPDHFPSRS

10.67

-6.19

-5.13

PPDHFPSRSQ

11.38

-10.46

-9.40
Q08412

ELPTQPVRKN

7.00

-11.70

-10.64

IELPTQPVRK

9.63

-7.38

-6.32

PQLPTRTKSG

10.31

-7.49

-6.43
P32855

NNAPTLPKRK

6.34

-9.58

-8.52

ATNNAPTLPK

14.37

-7.26

-6.20
Q06409

GKPRKTPRPP

8.70

-11.68

-10.62

RKTPRPPFPF

10.57

-8.82

-7.76

TGKPRKTPRP

12.84

-7.67

-6.61
P32634

PLPPQEKIPL

9.21

-8.74

-7.68

TVPTEPTRYN

10.19

-11.36

-10.30

PLPPVPKAPS

11.31

-8.97

-7.91
Q06833

NRRPVPRRPS

6.11

-11.96

-10.90

SNRRPVPRRP

8.22

-10.44

-9.38

PVPRRPSQPL

10.99

-8.47

-7.41
P50101

FPGSPIDKSI

14.30

-5.78

-4.72
P53118

ENPHDLPSHL

13.38

-4.67

-3.61

NPHDLPSHLG

14.63

-10.09

-9.03

VENPHDLPSH

14.97

-4.24

-3.18
Q12199

AAPATPPRHI

8.96

-10.77

-9.71

PNNPQCLHCG

13.23

-6.57

-5.51

NNPNNPQCLH

14.33

-7.20

-6.14
P19158

YDPSLPDTPT

14.26

-8.32

-7.26

SMTPVSPLGL

14.38

-5.08

-4.02
P38870

TTPERPKRKS

7.83

-13.22

-12.16

STPTTPERPK

7.99

-12.76

-11.70

PTTPERPKRK

9.16

-8.00

-6.94
P43638

PTNIPPPRGR

11.49

-9.10

-8.04

KGRPIPPHPD

11.64

-10.20

-9.14

PHPDAPKLPS

12.15

-7.56

-6.50
P53933

APPPLPNRQL

9.81

-12.11

-11.05

RRPPPPPIPS

10.65

-8.15

-7.09

YNDLPMELPH

11.58

-5.19

-4.13
P32790

LPPIKPPRPT

7.47

-12.29

-11.23

PPPAMPARPT

7.61

-12.61

-11.55

PAPLDPFKTG

12.46

-6.79

-5.73
P40020

EEPTSPTRQV

9.07

-10.31

-9.25

PPPLTPEKNL

10.87

-9.26

-8.20

RVLPPLPFPL

11.36

-8.79

-7.73
P38238

SLDPVQSPTN

14.03

-5.71

-4.65
P00175

PELVCPPYAP

13.37

-8.14

-7.08
Q08229

YNPTIPPRSK

6.56

-11.37

-10.31

DYNPTIPPRS

10.94

-5.40

-4.34

TNDYNPTIPP

13.23

-6.82

-5.76
P38930

AFPDMVPKHP

9.11

-10.52

-9.46

FPDMVPKHPT

11.93

-10.05

-8.99
Q12446

PAPPPPPRRG

7.21

-11.54

-10.48

PPPPRASRPT

8.09

-13.61

-12.55

APPPPPHRHV

9.32

-10.46

-9.40
Q12211

KRPKSGPRLD

10.19

-8.81

-7.75

DKRPKSGPRL

10.62

-5.14

-4.08

ENGNPLPKEP

13.58

-6.44

-5.38
Q06116

NSPELVPRSS

10.88

-10.57

-9.51

PNSPELVPRS

12.10

-4.04

-2.98

HSEPVEPFSA

12.25

-6.05

-4.99
P33336

PDRNLPSHPS

13.62

-9.26

-8.20

NLPSHPSSNN

14.40

-6.39

-5.33

RNLPSHPSSN

14.79

-4.24

-3.18
P50942

PRPCPPIRRK

5.54

-11.92

-10.86

PCPPIRRKSS

8.77

-9.50

-8.44

VPRPCPPIRR

10.59

-8.51

-7.45
Q06266

QFPSSPYRTV

10.44

-9.15

-8.09

SQFPSSPYRT

11.18

-7.87

-6.81

AIPSSPAFPG

12.46

-9.21

-8.15
Q00916

PRPPLSYKRP

6.99

-10.37

-9.31

PTDYPYAKRQ

8.85

-8.07

-7.01

VSRLFKPRPP

9.44

-8.90

-7.84
P07269

ASDSGPQRPK

10.46

-10.38

-9.32

ELPNTPDFLK

10.99

-10.56

-9.50
P40563

APPPVPKKPS

8.09

-10.78

-9.72

RAPPPVPKKP

11.68

-9.42

-8.36

KRRAPPPVPK

12.48

-7.87

-6.81
P10566

STRPIPAIPM

11.46

-8.34

-7.28

TRPIPAIPMD

14.41

-4.32

-3.26

PIPAIPMDLP

14.53

-7.12

-6.06
P38289

EDPENPSFIN

11.88

-9.45

-8.39

PENPSFINYR

13.32

-3.95

-2.89
P47030

DTETKPPRAP

10.88

-11.40

-10.34

AFPPEPSMSS

12.62

-8.19

-7.13

EAFPPEPSMS

14.57

-3.78

-2.72
P53901

PLPPIPTRDD

7.82

-12.14

-11.08

AMRPIPPLPT

9.50

-9.14

-8.08

NQPPLPPIPT

11.02

-9.16

-8.10
P32862

TVPSTPSRSN

9.95

-10.60

-9.54

SSPGSTPQRS

12.38

-5.48

-4.42

SPGSTPQRST

12.67

-8.17

-7.11
P31374

ISPERPSFRQ

8.37

-10.01

-8.95

GNNISPERPS

9.12

-9.63

-8.57

PLDFEQPRLP

9.71

-11.25

-10.19
P53169

IMPTLPPRPY

6.63

-14.27

-13.21

SVPIMPTLPP

11.11

-9.61

-8.55

PIMPTLPPRP

11.55

-6.90

-5.84
P53955

QRNPIPYPID

12.36

-6.23

-5.17

DSNQNDPRSP

12.56

-6.90

-5.84

RNPIPYPIDA

13.15

-4.39

-3.33

 


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