ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-28.PDB
Scoring matrix: LSB3_2A08-28_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.92
Foldx random average score for Saccharomyces cerevisiae: 19.184

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1477776
Proteins after disorder filtering: 4107
 Total fragments: 43854
Proteins after pattern filtering: 1839
 Total fragments: 6302
Proteins after MINT filtering: 65
 Total fragments: 384


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.92

-0.92

0.00
Best peptides

RPPIWRRRHR

0.00

-13.50

-12.58
         
Interactors      
P38140

QPDLPPRKIM

14.85

-12.08

-11.16

NIPPHPYPSS

15.58

-9.12

-8.20

NIQPDLPPRK

16.87

-7.11

-6.19
Q06604

KGPRMPSRGR

13.74

-11.02

-10.10

PTPPSPPAKR

13.94

-6.71

-5.79

FEKGPRMPSR

14.01

-8.92

-8.00
P09119

TPTTSPVKKS

17.01

-5.28

-4.36

LTPTTSPVKK

18.71

-5.68

-4.76
P24814

LHPPDIHPNL

16.28

-5.15

-4.23

IHPNLGPQLW

17.63

-6.77

-5.85

HPNLGPQLWL

19.09

-7.14

-6.22
P25604

PPKPKSPHLK

15.76

-8.21

-7.29

TPPLPPKPKS

16.11

-8.50

-7.58

LPPKPKSPHL

17.22

-8.90

-7.98
P40956

PPLPRRRATT

13.79

-9.70

-8.78

STPPLPRRRA

14.57

-9.76

-8.84

TTSTPPLPRR

15.45

-8.55

-7.63
P25623

PLPPHATPKN

16.34

-8.95

-8.03

LPKTVPISIS

16.54

-8.64

-7.72

QPPLQPQSKT

17.50

-7.81

-6.89
Q04322

DQAPLDRPQL

14.97

-11.44

-10.52

STPPTLPPRR

16.38

-9.20

-8.28

TPPTLPPRRI

17.66

-8.30

-7.38
P38266

PPKPFRRSQS

11.73

-7.84

-6.92

MPPPKPFRHG

11.93

-12.08

-11.16

ITPPRPPPSR

12.17

-5.93

-5.01
P47043

KPPQLPPKCS

15.73

-7.48

-6.56

SKPPQLPPKC

17.68

-5.99

-5.07

KNKPNPPPGS

18.93

-5.27

-4.35
P15891

EAAQPPLPSR

16.04

-6.82

-5.90

QPPLPSRNVA

16.27

-10.23

-9.31

TPSKSPAPVS

16.51

-5.88

-4.96
P40341

LNDPSNPVSK

18.48

-4.36

-3.44

PPPPKPPLND

18.86

-6.75

-5.83

PPPPPKPPLN

19.18

-7.00

-6.08
Q12134

QPVPSPMNSQ

16.99

-7.10

-6.18

THQPVPSPMN

17.85

-5.18

-4.26
P40494

PPRPPPKPLH

16.52

-10.35

-9.43

KPTLIPDNGN

17.75

-7.36

-6.44

QPPNMMPVTH

18.00

-7.35

-6.43
Q12200

VCPPSFPSRR

12.05

-8.24

-7.32

ESCPHLKPLK

13.31

-9.23

-8.31

PSDPCPLGGR

14.51

-8.74

-7.82
Q12344

TSPKLPPRGK

14.76

-7.60

-6.68

PKLPPRGKQR

15.25

-7.99

-7.07

SPKLPPRGKQ

16.51

-12.02

-11.10
P53238

RPIPPAPTHY

16.39

-8.48

-7.56

IPPAPTHYNN

18.50

-7.27

-6.35
P32660

TDPNRPKVTK

13.39

-7.70

-6.78

PMSPFEDTFQ

19.14

-3.66

-2.74

YDPTDPNRPK

19.15

-4.33

-3.41
P33400

ILPPLPVGIS

16.34

-7.17

-6.25

VQPPNAPSYQ

18.68

-7.15

-6.23

PNAPSYQSVQ

18.73

-4.66

-3.74
P53901

QPPLPPIPTR

14.16

-9.03

-8.11

NDPIILPPTF

14.78

-6.95

-6.03

LPPIPTRDDM

15.08

-11.88

-10.96
P38739

SPFHDPILPR

16.56

-6.13

-5.21

SPPNDPSTLA

18.48

-5.31

-4.39
Q04749

PLPVLPRRIS

12.89

-11.89

-10.97

NSPLPVLPRR

15.93

-8.50

-7.58

PVLPRRISTH

16.17

-8.25

-7.33
P04051

SLPHFPKNSK

15.57

-6.09

-5.17

RSLPHFPKNS

16.53

-5.75

-4.83

NPAMLPGSSN

18.95

-7.36

-6.44
P40325

PSLPWTYPPR

13.54

-8.67

-7.75

QPPRPPRPAA

14.66

-11.57

-10.65

VQPGDPRLGG

14.93

-7.92

-7.00
P47129

PNPPPNRSQR

13.33

-11.91

-10.99

NRKPNPPPNR

15.00

-10.38

-9.46

PPLLPPRNTM

16.59

-10.55

-9.63
P40453

PDLPIRLRKR

8.33

-10.64

-9.72

KPPDLPIRLR

11.90

-10.79

-9.87

PPDLPIRLRK

14.78

-12.39

-11.47
P40095

VLPPPRSPNR

14.24

-8.10

-7.18

RIPVLPPPRS

14.71

-8.09

-7.17

PRSPNRPTLS

17.69

-5.97

-5.05
Q12168

NDDPYFPQFR

14.64

-3.30

-2.38

PPPVPNRPGG

15.80

-12.36

-11.44

DDPYFPQFRS

16.38

-2.78

-1.86
P36125

PAGPQGQRRR

13.50

-8.93

-8.01

DLPAGPQGQR

15.29

-7.48

-6.56

LPAGPQGQRR

17.28

-8.90

-7.98
P40528

NDIPITPSHD

18.07

-7.33

-6.41

IPITPSHDNN

19.00

-8.13

-7.21
P36123

LFPPDHFPSR

12.60

-7.07

-6.15

TPKTPPRPKT

16.93

-9.72

-8.80

FPPDHFPSRS

17.10

-6.20

-5.28
Q08412

VPPQLPTRTK

14.23

-8.32

-7.40

EDVPPQLPTR

15.28

-6.21

-5.29

DIELPTQPVR

15.30

-7.98

-7.06
P32855

TNNAPTLPKR

15.03

-7.58

-6.66
Q06409

KPRKTPRPPF

15.36

-11.72

-10.80

KTPRPPFPFF

15.92

-9.82

-8.90

PRNPDPYGFE

17.45

-8.33

-7.41
P32634

LPPVPKAPSR

14.65

-9.74

-8.82

VPTEPTRYNY

16.58

-10.62

-9.70

TETVPTEPTR

16.90

-8.03

-7.11
Q06833

RRPVPRRPSQ

13.24

-12.25

-11.33

VPRRPSQPLN

16.99

-8.88

-7.96

RRPSQPLNTL

17.07

-7.61

-6.69
P50101

PGSPIDKSIG

17.18

-8.56

-7.64

VFPGSPIDKS

18.48

-5.25

-4.33
P53118

VENPHDLPSH

16.40

-10.78

-9.86

ENPHDLPSHL

17.38

-5.42

-4.50
Q12199

APATPPRHIC

16.55

-11.04

-10.12

ITTPSVQPTA

17.62

-4.69

-3.77

TAAPATPPRH

18.41

-7.99

-7.07
P19158

MTPVSPLGLD

17.45

-6.73

-5.81

PSLPDTPTMS

19.03

-3.81

-2.89
P38870

TPTTPERPKR

10.63

-11.38

-10.46

TTPERPKRKS

15.40

-7.40

-6.48

PTTPERPKRK

16.44

-7.52

-6.60
P43638

DAPKLPSAFR

12.49

-10.29

-9.37

VPTNIPPPRG

15.85

-8.41

-7.49

PTNIPPPRGR

16.42

-7.42

-6.50
P53933

RVAPPPLPNR

14.93

-10.74

-9.82

PPPPIPSTQK

15.33

-9.06

-8.14

APPPLPNRQL

16.82

-8.44

-7.52
P32790

EGPPPAMPAR

15.70

-7.80

-6.88

PPIKPPRPTS

15.83

-11.99

-11.07

PPAMPARPTA

16.54

-10.32

-9.40
P40020

VLPPLPFPLY

12.27

-11.07

-10.15

RPPPLTPEKN

14.05

-8.34

-7.42

YLTPESPLNR

14.32

-8.78

-7.86
P38238

VQSPTNPPYK

18.71

-6.54

-5.62
P00175

FLPNHPGGQD

18.27

-6.37

-5.45
Q08229

YNPTIPPRSK

15.93

-6.84

-5.92

NPTIPPRSKD

16.06

-11.32

-10.40

PTPVQPGGHY

17.31

-7.79

-6.87
P38930

QAFPDMVPKH

17.04

-6.45

-5.53
Q12446

APPPPPRASR

12.10

-13.05

-12.13

LPQLPNRNNR

12.59

-12.28

-11.36

RPVPPPPPMR

12.72

-9.42

-8.50
Q12211

KRPKSGPRLD

17.16

-5.48

-4.56

NGNPLPKEPR

17.29

-7.36

-6.44

DKRPKSGPRL

18.22

-6.30

-5.38
Q06116

SPELVPRSST

17.86

-10.52

-9.60
P50942

VPRPCPPIRR

11.65

-11.07

-10.15

PCPPIRRKSS

12.42

-10.00

-9.08

RPCPPIRRKS

14.25

-11.34

-10.42
Q06266

VDPYSPPNYK

16.48

-5.68

-4.76

FPSSPYRTVD

17.53

-9.07

-8.15

VDAIPSSPAF

17.83

-7.25

-6.33
Q00916

RPTDYPYAKR

10.63

-10.15

-9.23

KPRPPLSYKR

14.03

-9.74

-8.82

FKPRPPLSYK

15.94

-9.69

-8.77
P07269

SDSGPQRPKR

13.43

-10.58

-9.66

LPNTPDFLKN

17.34

-10.12

-9.20
P40563

RRAPPPVPKK

16.51

-7.70

-6.78

PAGTPNVPTR

18.74

-8.65

-7.73

SEVTPKVPER

18.83

-6.39

-5.47
P10566

RPIPAIPMDL

17.75

-6.21

-5.29

PAIPMDLPDY

18.28

-6.42

-5.50

TRPIPAIPMD

18.61

-7.34

-6.42
P38289

PENPSFINYR

14.32

-9.23

-8.31

VPTNDPSGIL

17.81

-6.43

-5.51

DPENPSFINY

18.46

-10.44

-9.52
P32863

LPDRPPNGIG

19.07

-8.43

-7.51
P32862

ASSPGSTPQR

17.30

-5.32

-4.40

VPSTPSRSNS

17.35

-10.35

-9.43

YRPPNPPANN

18.10

-5.91

-4.99
P39743

YSNPLTSPVA

17.99

-5.42

-4.50
P31374

NISPERPSFR

12.90

-6.92

-6.00

ISPERPSFRQ

17.26

-6.16

-5.24

FEQPRLPSTA

17.29

-7.22

-6.30
P53169

VPIMPTLPPR

16.99

-7.24

-6.32

IMPTLPPRPY

18.44

-8.21

-7.29
P53955

QRNPIPYPID

14.86

-9.94

-9.02

 


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