ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-27.PDB
Scoring matrix: LSB3_2A08-27_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 16.69
Foldx random average score for Saccharomyces cerevisiae: 19.269

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 2114167
Proteins after disorder filtering: 4764
 Total fragments: 155995
Proteins after pattern filtering: 2331
 Total fragments: 23846
Proteins after MINT filtering: 75
 Total fragments: 1318


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

16.69

-0.81

0.00
Best peptides

RKPMDRWWR

0.00

-1.17

-0.36
         
Interactors      
P38140

NIQPDLPPR

10.21

-5.88

-5.07

PDLPPRKIM

10.83

-6.52

-5.71

NIPPHPYPS

10.90

-5.21

-4.40
Q06604

RVKPAPPVS

8.62

-6.74

-5.93

YSNIPSSKP

9.16

-6.24

-5.43

PKPTPPSPP

9.72

-2.13

-1.32
P09119

SAQVPLTPT

11.56

-3.81

-3.00

VPLTPTTSP

12.94

0.12

0.93

LTPTTSPVK

13.52

0.57

1.38
P24814

RLHPPDIHP

8.35

-7.38

-6.57

PPDIHPNLG

10.14

-5.06

-4.25

LHPPDIHPN

11.18

-5.55

-4.74
P25604

LKPPLPPPP

8.97

-7.25

-6.44

PKSPHLKPP

9.69

-4.11

-3.30

HLKPPLPPP

10.04

-6.43

-5.62
P40956

PKNVPFPFD

8.01

-5.26

-4.45

PPLPRRRAT

11.52

-4.35

-3.54

FWNPKNVPF

12.21

-5.21

-4.40
P25623

PKTVPISIS

9.17

-4.71

-3.90

PLPPHATPK

11.57

-2.71

-1.90

KPLPVEPAS

12.26

-3.93

-3.12
Q12532

PFKPYINGG

13.38

-4.32

-3.51
P50942

RPCPPIRRK

6.62

-8.44

-7.63

RHSTPKPLP

6.97

-5.54

-4.73

GKIVPRPCP

8.67

-5.34

-4.53
Q04322

NATPSKSPT

11.61

-4.16

-3.35

TPPTLPPRR

12.00

0.31

1.12

SSSTPPTLP

13.09

-1.07

-0.26
P38266

RAVPILPPR

6.82

-7.97

-7.16

RAPTPPAPS

7.09

-5.18

-4.37

RNNVEPPPP

7.19

-7.60

-6.79
P47043

KNKPNPPPG

10.37

-6.60

-5.79

SKPPQLPPK

10.70

-5.60

-4.79

KPNPPPGSD

12.82

-4.51

-3.70
P15891

RRATPEKKP

5.04

-5.61

-4.80

RATPEKKPK

7.52

-7.30

-6.49

KKEPVKTPS

9.44

-4.04

-3.23
P40341

RNIPPPPPP

7.22

-9.59

-8.78

SRNIPPPPP

8.92

-7.11

-6.30

PPPPKPPLN

10.10

-6.96

-6.15
Q12134

HQPVPSPMN

11.17

-2.82

-2.01

QPVPSPMNS

11.49

-5.38

-4.57

THQPVPSPM

14.80

-5.47

-4.66
P40494

PRPPPKPLH

9.16

-7.48

-6.67

SRPPRPPPK

9.63

-6.78

-5.97

KSRPPRPPP

9.67

-6.45

-5.64
Q12200

PCPVPRSFE

10.53

-4.47

-3.66

EVCPPSFPS

12.16

-5.20

-4.39

ESCPHLKPL

12.36

-2.89

-2.08
Q12344

PKLPPRGKQ

10.10

-5.47

-4.66

PPLPPRQNV

11.71

-4.34

-3.53

ATSTSPKLP

12.72

-6.03

-5.22
P53189

TLQPSTIPQ

15.91

-3.37

-2.56
P53238

GRPIPPAPT

8.78

-6.33

-5.52

RPIPPAPTH

9.01

-7.89

-7.08

QKPAGRPIP

11.41

-5.07

-4.26
P32660

YDPTDPNRP

9.38

-2.39

-1.58

HAPMSPFED

9.42

-2.58

-1.77

GHAPMSPFE

11.34

-6.67

-5.86
P33400

SPQILPPLP

10.70

-7.06

-6.25

YVQPPNAPS

10.96

-6.01

-5.20

QILPPLPVG

11.62

-3.68

-2.87
P53901

MRPIPPLPT

8.28

-1.61

-0.80

RPIPPLPTE

8.64

-7.59

-6.78

NDPIILPPT

9.55

-5.50

-4.69
P38739

LASPFHDPI

12.38

-5.35

-4.54

AGSPPNDPS

13.06

-4.98

-4.17

GSPPNDPST

13.92

-3.72

-2.91
Q04749

PLPVLPRRI

10.44

-3.72

-2.91

TNPVFNPRK

11.21

-6.40

-5.59

VFNPRKPTL

12.20

-4.17

-3.36
P04051

RSLPHFPKN

7.42

-7.61

-6.80

NPAMLPGSS

12.40

-0.91

-0.10

PHFPKNSKT

12.46

-5.35

-4.54
P43603

RFTAPTSPS

10.62

-7.09

-6.28

GRFTAPTSP

13.11

0.94

1.75

FTAPTSPST

13.47

-3.72

-2.91
P40325

RPPPRPQQN

7.32

-10.04

-9.23

RPSTMPATS

8.78

-3.24

-2.43

LPWTYPPRF

9.63

-2.63

-1.82
P47129

NRKPNPPPN

9.30

-6.18

-5.37

RKPNPPPNR

9.79

-6.33

-5.52

KPNPPPNRS

10.43

-5.80

-4.99
P40453

RKRPPPPPP

4.80

-10.42

-9.61

WKPPDLPIR

5.66

-7.98

-7.17

RPPPPPPVS

6.90

-9.07

-8.26
P40095

RIPVLPPPR

5.49

-8.65

-7.84

VLPPPRSPN

9.93

-6.18

-5.37

NRIPVLPPP

10.36

-5.26

-4.45
Q12168

RGPPPLPPR

5.42

-9.09

-8.28

HPVPKPNID

9.89

-6.68

-5.87

PPPVPNRPG

10.17

-1.52

-0.71
P36125

PAGPQGQRR

12.86

-4.88

-4.07

NDLPAGPQG

14.06

-4.31

-3.50

DLPAGPQGQ

17.13

-2.63

-1.82
P53142

PLIEPTTTN

19.19

0.39

1.20
P40528

LNDIPITPS

10.27

-5.22

-4.41

DIPITPSHD

10.87

-1.54

-0.73

IPITPSHDN

13.18

-1.16

-0.35
P36123

RSQPSDPKL

7.83

-7.06

-6.25

PKTPPRPKT

8.49

-5.80

-4.99

LFPPDHFPS

10.20

-6.30

-5.49
Q08412

QPLPPEPLD

10.43

-6.34

-5.53

KWQPLPPEP

12.01

-5.44

-4.63

DEDVPPQLP

13.26

-5.52

-4.71
Q06697

SGGPRKDPI

12.64

-4.80

-3.99

SSGGPRKDP

18.85

-2.50

-1.69
P40041

NGRTLPPVP

11.35

-1.36

-0.55

PLSPPSSSN

14.02

-3.73

-2.92

KIPLSPPSS

17.02

-1.57

-0.76
Q06409

RKTPRPPFP

3.81

-10.21

-9.40

PRKTPRPPF

8.82

-2.27

-1.46

PRNPDPYGF

11.00

-4.71

-3.90
P32634

VLNIPLPPQ

9.06

-5.81

-5.00

LPPVPKAPS

9.14

-5.67

-4.86

LPIVPNPNL

10.38

-5.73

-4.92
Q06833

RRPVPRRPS

3.08

-9.86

-9.05

RPVPRRPSQ

6.94

-7.68

-6.87

NRRPVPRRP

10.13

-5.09

-4.28
P53118

VENPHDLPS

14.46

-4.63

-3.82

NPHDLPSHL

16.96

0.39

1.20

PHDLPSHLG

18.71

-2.96

-2.15
Q12199

APATPPRHI

10.35

-0.98

-0.17

PATPPRHIC

10.96

-4.73

-3.92

CNNPNNPQC

13.09

-3.50

-2.69
P19158

MTPVSPLGL

13.11

-0.47

0.34

SMTPVSPLG

13.23

-4.36

-3.55

EYDPSLPDT

13.40

-3.14

-2.33
P38870

HSTPKPPPN

10.43

-6.74

-5.93

IHSTPKPPP

11.32

-3.25

-2.44

PKPPPNDKD

11.51

-5.54

-4.73
P43638

RPIPPHPDA

8.29

-8.34

-7.53

KGRPIPPHP

8.70

-5.67

-4.86

GRPIPPHPD

8.75

-6.80

-5.99
P53933

RRPPPPPIP

4.57

-10.44

-9.63

RRRPPPPPI

5.09

-11.07

-10.26

RPPPPPIPS

8.16

-9.39

-8.58
P50101

IGTVFPGSP

11.61

0.35

1.16

PGSPIDKSI

12.82

-4.02

-3.21

TVFPGSPID

13.95

-3.80

-2.99
P40020

RVLPPLPFP

6.08

-9.35

-8.54

RPPPLTPEK

8.28

-8.28

-7.47

KSRVLPPLP

9.88

-7.18

-6.37
P38238

QSPTNPPYK

10.56

-2.70

-1.89

LDPVQSPTN

12.69

-3.42

-2.61

SLDPVQSPT

14.51

-3.52

-2.71
P00175

RFLPNHPGG

8.41

-7.88

-7.07

LVCPPYAPG

11.88

-5.47

-4.66

VCPPYAPGE

13.38

-4.29

-3.48
Q08229

RPLPSTPNE

8.29

-6.55

-5.74

YNPTIPPRS

9.60

-3.83

-3.02

NPTIPPRSK

10.39

-4.03

-3.22
P38930

FPDMVPKHP

7.30

-2.69

-1.88

PDMVPKHPT

11.05

-3.63

-2.82

QAFPDMVPK

12.63

-5.71

-4.90
Q12446

RRGPAPPPP

6.07

-9.74

-8.93

RPVPPPPPM

6.23

-9.86

-9.05

NRPVPPPPP

7.69

-6.55

-5.74
P32855

NAPTLPKRK

10.83

-1.85

-1.04

YSNPSSSPN

11.57

-5.36

-4.55

NNAPTLPKR

12.10

-4.34

-3.53
Q12211

DKRPKSGPR

11.08

-4.18

-3.37

RPKSGPRLD

11.75

-6.15

-5.34

NGNPLPKEP

12.09

-5.20

-4.39
Q06116

GNGVKPFYP

10.39

-5.86

-5.05

HSEPVEPFS

11.31

-5.80

-4.99

GVKPFYPVT

12.49

-4.58

-3.77
P33336

RNLPSHPSS

9.93

-5.06

-4.25

PSHPSSNNM

14.51

-3.10

-2.29

TCDPEDYPT

16.22

-4.38

-3.57
P32793

HGPTHPSNM

10.26

-0.63

0.18

PTHPSNMSN

15.16

-3.14

-2.33

GHGPTHPSN

15.67

-3.58

-2.77
P38090

PNDPDLTAA

13.50

-2.57

-1.76

VCSPNDPDL

13.86

-2.76

-1.95

CSPNDPDLT

16.92

-4.12

-3.31
Q06266

YRTVDPYSP

8.15

-2.07

-1.26

VDAIPSSPA

10.10

-5.99

-5.18

YPTPFPSSS

10.85

-4.71

-3.90
Q00916

KRPTDYPYA

7.59

-3.17

-2.36

YKRPTDYPY

9.23

-5.58

-4.77

KPRPPLSYK

9.68

-5.51

-4.70
P07269

LPNTPDFLK

10.16

-1.41

-0.60

DSGPQRPKR

11.90

-4.10

-3.29

PNTPDFLKN

12.81

-4.09

-3.28
P40563

RAPPPVPKK

6.46

-8.79

-7.98

RRAPPPVPK

7.70

-8.22

-7.41

PPPVPKKPS

9.38

-1.65

-0.84
P10566

RPIPAIPMD

7.73

-9.20

-8.39

AIPMDLPDY

9.72

-4.71

-3.90

IPAIPMDLP

10.70

-0.29

0.52
P38289

MYDVPTNDP

12.26

-1.64

-0.83

DVPTNDPSG

13.17

1.32

2.13

YDVPTNDPS

13.61

-4.80

-3.99
P47030

AFPPEPSMS

12.59

-5.18

-4.37

EAFPPEPSM

13.08

-3.63

-2.82

FPPEPSMSS

14.79

-2.78

-1.97
P32790

LPPIKPPRP

7.34

-6.84

-6.03

PPAMPARPT

9.61

-4.10

-3.29

EGPPPAMPA

10.50

-5.80

-4.99
P32863

PDRPPNGIG

13.52

-5.32

-4.51

LPDRPPNGI

16.46

-0.66

0.15
P32862

YRPPNPPAN

8.99

-6.56

-5.75

NYRPPNPPA

11.21

-6.00

-5.19

HMNPSNSPN

11.70

-4.46

-3.65
P39743

NATIPEDNP

12.06

-3.94

-3.13

YSNPLTSPV

12.26

-5.60

-4.79

AYSNPLTSP

17.89

-1.04

-0.23
P31374

FRKTKPPPP

6.84

-4.49

-3.68

KPGTPVFPN

10.18

-1.94

-1.13

KPPPPLDFE

10.42

-5.85

-5.04
P53169

SVPIMPTLP

9.82

-5.87

-5.06

VPIMPTLPP

10.51

-3.55

-2.74

ANSVPIMPT

10.69

-5.93

-5.12
P53955

RNPIPYPID

5.40

-9.96

-9.15

QRNPIPYPI

10.09

-5.88

-5.07

NPIPYPIDA

13.82

-4.40

-3.59

 


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