ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-17.PDB
Scoring matrix: LSB3_2A08-17_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.64
Foldx random average score for Saccharomyces cerevisiae: 18.265

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1600997
Proteins after disorder filtering: 4598
 Total fragments: 89619
Proteins after pattern filtering: 1975
 Total fragments: 7032
Proteins after MINT filtering: 67
 Total fragments: 400


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.64

5.26

0.00
Best peptides

FKYRNGKRR

0.00

-3.71

-8.97
         
Interactors      
P38140

IPPHPYPSS

14.45

-0.11

-5.37

NIQPDLPPR

14.83

-2.14

-7.40

PDLPPRKIM

15.24

-1.43

-6.69
Q06604

EKGPRMPSR

9.63

-1.35

-6.61

PPSPPAKRI

11.15

-5.84

-11.10

PLLPTRPNK

12.90

-3.48

-8.74
P09119

LTPTTSPVK

17.65

1.76

-3.50
P24814

HPPDIHPNL

14.87

-0.90

-6.16

IHPNLGPQL

16.57

0.14

-5.12

DIHPNLGPQ

18.17

-1.47

-6.73
P25604

PPKPNTQLQ

15.22

-1.52

-6.78

PPKPKSPHL

15.91

-2.72

-7.98

LPPKPNTQL

16.27

-1.38

-6.64
P40956

TSTPPLPRR

10.89

-4.78

-10.04

TPPLPRRRA

14.18

-7.84

-13.10

PPLPRRRAT

16.14

-2.04

-7.30
P25623

LPPHATPKN

14.22

-1.36

-6.62

EPASPSISL

14.53

0.23

-5.03

PVEPASPSI

14.69

-1.18

-6.44
P50942

RPCPPIRRK

8.16

-6.70

-11.96

PPPPPTSRH

11.83

-4.75

-10.01

LPPVPALSL

14.52

1.70

-3.56
Q04322

STPPTLPPR

15.74

-0.57

-5.83

TPPTLPPRR

16.87

-4.37

-9.63

QAPLDRPQL

17.44

-0.68

-5.94
P38266

PPKPFRRSQ

11.49

-2.80

-8.06

APTPPAPSR

11.84

-2.54

-7.80

LPPPPTHRD

12.06

-5.01

-10.27
P47043

PTSPQQNSK

14.76

0.16

-5.10

SKPPQLPPK

15.52

-0.18

-5.44

ASDPTSPQQ

16.86

0.04

-5.22
P15891

AAQPPLPSR

13.34

-0.67

-5.93

RATPEKKPK

14.12

-1.01

-6.27

AAPPPPPRR

17.31

-5.32

-10.58
P40341

KPPLNDPSN

15.29

-2.05

-7.31

PPPPPKPPL

17.95

-3.05

-8.31
Q12134

PVPSPMNSQ

16.90

2.07

-3.19
P40494

PRPPPKPLH

16.37

-0.16

-5.42
Q12200

VCPPSFPSR

11.46

-2.38

-7.64

PPSFPSRRC

12.96

-4.55

-9.81

CPPSFPSRR

14.04

-5.08

-10.34
Q12344

PKLPPRGKQ

15.05

-1.67

-6.93

STSPKLPPR

16.38

-1.94

-7.20

TSSPPLPPR

17.01

-2.38

-7.64
P53238

RPIPPAPTH

15.31

-1.30

-6.56

PPAPTHYNN

15.34

-1.70

-6.96

IPPAPTHYN

16.57

-0.98

-6.24
P32660

GYDPTDPNR

11.42

-0.87

-6.13

DPTDPNRPK

16.16

0.19

-5.07

PTDPNRPKV

16.43

-1.51

-6.77
P33400

VQPPNAPSY

13.99

-0.25

-5.51

PNAPSYQSV

18.23

0.91

-4.35
P38739

GSPPNDPST

15.32

2.09

-3.17

LASPFHDPI

16.76

-0.21

-5.47

PFHDPILPR

17.00

0.72

-4.54
Q04749

SPLPVLPRR

8.73

-4.17

-9.43

TNPVFNPRK

11.86

-2.35

-7.61

ITNPVFNPR

16.09

-0.35

-5.61
P04051

LPHFPKNSK

13.98

-2.31

-7.57

RSLPHFPKN

14.68

-0.08

-5.34

VNPAMLPGS

18.16

0.97

-4.29
P43603

FTAPTSPST

15.96

1.07

-4.19

APTSPSTSS

16.53

1.46

-3.80
P40325

YVQPGDPRL

10.77

-5.03

-10.29

LYVQPGDPR

13.41

-1.17

-6.43

RPPRPAANL

13.59

-3.21

-8.47
P47129

NTLPNRKPN

15.94

0.16

-5.10

PNPPPNRSQ

15.95

-1.37

-6.63

SGPPLLPPR

16.11

-1.53

-6.79
P40453

PDLPIRLRK

10.26

-3.15

-8.41

WKPPDLPIR

10.74

-0.97

-6.23

DCPRCGPTA

15.88

0.88

-4.38
P40095

LPPPRSPNR

9.81

-3.41

-8.67

FPDSPSSSS

14.47

0.42

-4.84

PRSPNRPTL

15.35

-0.42

-5.68
Q12168

DPYFPQFRS

12.45

-3.85

-9.11

RGPPPLPPR

14.30

-2.60

-7.86

PPVPNRPGG

15.27

-2.05

-7.31
P36125

PAGPQGQRR

8.27

-3.73

-8.99

LPAGPQGQR

14.75

-2.16

-7.42

NDLPAGPQG

15.40

-0.03

-5.29
P32793

GHGPTHPSN

15.13

0.20

-5.06

GPTHPSNMS

16.45

0.88

-4.38

PTHPSNMSN

16.66

1.07

-4.19
P40528

NDIPITPSH

13.88

1.08

-4.18

PITPSHDNN

17.38

-1.49

-6.75
P36123

FPPDHFPSR

8.31

-1.58

-6.84

RSQPSDPKL

13.64

-0.80

-6.06

YTTPKTPPR

14.07

-2.74

-8.00
Q08412

IELPTQPVR

13.60

-2.16

-7.42

DVPPQLPTR

14.83

-2.46

-7.72

QPLPPEPLD

16.38

0.02

-5.24
P32855

NNAPTLPKR

12.03

-2.08

-7.34

SNPSSSPNS

17.63

1.57

-3.69

NAPTLPKRK

18.15

-2.39

-7.65
Q06409

GKPRKTPRP

15.95

-4.40

-9.66

TGKPRKTPR

16.61

-1.65

-6.91

SPFSPFNSS

16.97

1.99

-3.27
P32634

PPVPKAPSR

11.10

-2.48

-7.74

IPLPPQEKI

13.91

-3.82

-9.08

ETVPTEPTR

14.78

-0.19

-5.45
Q06833

RPVPRRPSQ

9.74

-3.05

-8.31

FPVPPSASN

13.98

-1.25

-6.51

RRPVPRRPS

16.26

1.28

-3.98
P50101

PGSPIDKSI

14.71

0.26

-5.00

FPGSPIDKS

16.47

-0.06

-5.32

GTVFPGSPI

17.05

0.41

-4.85
P53118

ENPHDLPSH

13.81

0.19

-5.07
Q12199

CNNPNNPQC

16.35

-1.56

-6.82

TAAPATPPR

16.40

-2.39

-7.65

PATPPRHIC

17.48

-0.23

-5.49
P19158

SMTPVSPLG

18.11

0.71

-4.55

PSSPPSSSS

18.22

1.62

-3.64

PSLPDTPTM

18.25

0.60

-4.66
P38870

PTTPERPKR

11.69

-2.22

-7.48

TPERPKRKS

15.80

-2.65

-7.91

SSTPTTPER

16.21

1.19

-4.07
P43638

PKLPSAFRK

9.09

-2.98

-8.24

PPHPDAPKL

15.06

-1.59

-6.85

IPPHPDAPK

15.49

-2.40

-7.66
P53933

VAPPPLPNR

13.54

-1.94

-7.20

NDLPMELPH

16.61

0.82

-4.44

PPPPPIPST

17.68

-0.23

-5.49
P32790

GPPPAMPAR

11.18

-2.61

-7.87

APAPLDPFK

14.42

-1.66

-6.92
P40020

RPPPLTPEK

14.09

-1.53

-6.79

SEEPTSPTR

14.95

0.46

-4.80

YLTPESPLN

15.14

-0.36

-5.62
P00175

RFLPNHPGG

14.73

-0.85

-6.11

LPNHPGGQD

15.64

-0.70

-5.96
Q08229

PSTPNEDSR

12.26

-0.43

-5.69

RPLPSTPNE

13.66

-0.50

-5.76

PVQPGGHYK

13.74

-1.13

-6.39
P38930

QAFPDMVPK

15.87

1.02

-4.24

AFPDMVPKH

16.89

1.00

-4.26
Q12446

RPLPQLPNR

9.34

-4.22

-9.48

PPPPPRASR

10.95

-4.73

-9.99

PPASPEVRK

11.33

-3.57

-8.83
Q12211

KRPKSGPRL

7.69

-4.65

-9.91

DKRPKSGPR

14.50

-1.02

-6.28
Q06116

NSPELVPRS

15.16

-1.53

-6.79

PNSPELVPR

15.73

-0.11

-5.37
P33336

RNLPSHPSS

12.99

-0.33

-5.59

LPSHPSSNN

16.37

-0.88

-6.14

PSHPSSNNM

16.82

-0.07

-5.33
P40041

PLSPPSSSN

17.46

-0.40

-5.66
P38090

VCSPNDPDL

17.51

0.08

-5.18
Q06266

SQFPSSPYR

13.91

-0.91

-6.17

KQQPNCPSS

14.31

0.05

-5.21

QPNCPSSNY

15.48

-0.53

-5.79
Q00916

PRPPLSYKR

12.38

-1.07

-6.33

KPRPPLSYK

14.59

-2.59

-7.85

RLFKPRPPL

15.06

-2.62

-7.88
P07269

DSGPQRPKR

11.78

-1.87

-7.13

LPNTPDFLK

14.63

-2.14

-7.40

NAPDEDPNL

15.35

0.56

-4.70
P40563

PSERPKRRA

12.81

-3.55

-8.81

NSQPQGPSD

13.99

1.17

-4.09

RAPPPVPKK

15.83

-2.15

-7.41
P10566

RPIPAIPMD

14.91

-0.86

-6.12
P38289

DVPTNDPSG

16.35

1.06

-4.20

PENPSFINY

16.66

-0.01

-5.27
P47030

FPPEPSMSS

12.91

0.13

-5.13

EAFPPEPSM

14.84

-0.30

-5.56
P53901

PPLPPIPTR

15.19

-1.90

-7.16

PPLPTTSNS

16.50

-0.34

-5.60

PNSHPHPSG

16.63

0.40

-4.86
P32862

NTVPSTPSR

11.36

0.42

-4.84

MNPSNSPNS

14.54

-0.80

-6.06

VPSTPSRSN

15.62

-0.52

-5.78
P31374

SPERPSFRQ

10.88

-4.83

-10.09

NISPERPSF

12.73

-1.14

-6.40

FEQPRLPST

14.81

0.59

-4.67
P53169

PIMPTLPPR

15.22

-2.24

-7.50

SPAQPSASL

15.33

0.33

-4.93

NSVPIMPTL

17.87

1.28

-3.98

 


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