ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-16.PDB
Scoring matrix: LSB3_2A08-16_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.35
Foldx random average score for Saccharomyces cerevisiae: 20.860

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1606087
Proteins after disorder filtering: 4671
 Total fragments: 110310
Proteins after pattern filtering: 2109
 Total fragments: 9097
Proteins after MINT filtering: 72
 Total fragments: 463


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

19.35

3.11

0.00
Best peptides

FFRIRSRRG

0.00

-3.81

-6.92
         
Interactors      
P38140

IPPHPYPSS

16.77

-1.45

-4.56

IQPDLPPRK

17.41

-0.64

-3.75

PHPYPSSNQ

20.77

0.90

-2.21
Q06604

KGPRMPSRG

12.07

-3.73

-6.84

LLPTRPNKA

12.54

-1.32

-4.43

PPPLPTRRD

13.12

-5.22

-8.33
P09119

PTTSPVKKS

16.61

0.97

-2.14

TPTTSPVKK

17.30

-0.73

-3.84

LTPTTSPVK

18.53

1.66

-1.45
P24814

PPDIHPNLG

12.62

-4.28

-7.39

NSTRPQMPS

19.39

1.48

-1.63

HPNLGPQLW

20.53

-1.38

-4.49
P25604

PPLPPKPKS

15.63

-3.06

-6.17

PPPQPASNA

17.53

-1.45

-4.56

KPKSPHLKP

17.81

-2.08

-5.19
P40956

TPPLPRRRA

10.04

-5.89

-9.00

STPPLPRRR

16.73

-0.08

-3.19

TSTPPLPRR

17.18

0.69

-2.42
P25623

LPPHATPKN

14.28

-2.12

-5.23

PPSTPQQSS

17.09

-2.58

-5.69

PPLQPQSKT

18.00

2.00

-1.11
Q12532

PFKPYINGG

19.20

-0.74

-3.85
P50942

PSPQPSVVG

13.63

-0.18

-3.29

PRPCPPIRR

15.10

0.14

-2.97

PPPPTSRHN

16.41

-1.37

-4.48
Q04322

TPPTLPPRR

14.34

-3.72

-6.83

ATPSKSPTS

16.88

1.69

-1.42

TSPPLPPRA

17.22

0.34

-2.77
P38266

PPPKPFRRS

9.40

-4.16

-7.27

PPPKPFRHG

10.16

-4.44

-7.55

GQPLPPPRG

12.44

-4.65

-7.76
P47043

KPPQLPPKC

12.86

-1.79

-4.90

DPTSPQQNS

18.28

0.20

-2.91

PPQLPPKCS

18.57

-3.68

-6.79
P15891

APPPPPRRA

14.00

-4.21

-7.32

QPPLPSRNV

16.66

-0.43

-3.54

RRATPEKKP

16.76

-0.88

-3.99
P40341

KPPLNDPSN

17.15

-3.15

-6.26

PPPKPPLND

19.90

-2.94

-6.05

PPPPKPPLN

20.36

-1.13

-4.24
Q12134

HQPVPSPMN

15.25

2.73

-0.38
P40494

KPTLIPDNG

15.70

-4.41

-7.52

RPPRPPPKP

16.66

-3.36

-6.47

PTLIPDNGN

18.26

1.88

-1.23
Q12200

PPSFPSRRC

9.43

-3.72

-6.83

APSDPCPLG

13.02

-1.66

-4.77

CPPSFPSRR

14.55

-2.14

-5.25
Q12344

TSPKLPPRG

10.99

-4.06

-7.17

SPPLPPRQN

17.97

-4.64

-7.75

SSPPLPPRQ

19.30

-0.14

-3.25
P53238

IPPAPTHYN

16.67

-0.08

-3.19
P32660

DPNRPKVTK

18.60

-0.99

-4.10

YPPGYDPTD

19.36

0.86

-2.25

DPTDPNRPK

20.50

-0.57

-3.68
P33400

PPNAPSYQS

17.66

0.73

-2.38

LPPLPVGIS

17.86

-2.25

-5.36

QPPNAPSYQ

18.89

0.38

-2.73
P38739

PPNDPSTLA

14.89

-0.65

-3.76

TSPSTAPSS

20.56

2.17

-0.94
Q04749

LPVLPRRIS

14.53

-4.22

-7.33

TNPVFNPRK

16.19

1.79

-1.32

SPLPVLPRR

16.55

-0.09

-3.20
P04051

RSLPHFPKN

15.52

1.91

-1.20

NPAMLPGSS

18.04

-2.78

-5.89

PAMLPGSSN

18.43

-0.71

-3.82
P43603

APTSPSTSS

16.64

-0.16

-3.27

RFTAPTSPS

19.60

-0.57

-3.68
P40325

LPWTYPPRF

11.86

-3.21

-6.32

QPGDPRLGG

14.95

-2.16

-5.27

HQSRPHQRP

16.66

-1.16

-4.27
P47129

GPPLLPPRN

14.37

-4.53

-7.64

KPNPPPNRS

14.42

-3.65

-6.76

NNTLPNRKP

18.63

-1.13

-4.24
P40453

DCPRCGPTA

16.90

-0.66

-3.77

CPRCGPTAS

18.07

-0.65

-3.76

VPEPPSWKP

18.18

-2.64

-5.75
P40095

IPVLPPPRS

12.60

-7.03

-10.14

FPDSPSSSS

14.36

-1.47

-4.58

RSPNRPTLS

16.28

1.52

-1.59
Q12168

DPYFPQFRS

12.06

0.08

-3.03

PPPVPNRPG

14.74

-3.41

-6.52

GPPPLPPRA

16.10

-1.65

-4.76
P36125

PAGPQGQRR

16.43

1.52

-1.59

NDLPAGPQG

19.85

0.09

-3.02

LPAGPQGQR

20.15

-1.19

-4.30
P53142

PLIEPTTTN

20.70

0.18

-2.93
P40528

IPITPSHDN

14.35

-0.29

-3.40

DIPITPSHD

20.51

0.50

-2.61
P36123

PPDHFPSRS

14.17

-2.96

-6.07

FPPDHFPSR

15.41

-0.57

-3.68

TTPKTPPRP

19.20

-2.04

-5.15
Q08412

LPTQPVRKN

12.77

-4.34

-7.45

ELPTQPVRK

16.02

-1.05

-4.16

VPPQLPTRT

17.60

-0.70

-3.81
P32793

GPTHPSNMS

14.21

-1.09

-4.20
Q06409

TPRNPDPYG

11.25

-1.22

-4.33

TPRPPFPFF

17.06

-0.84

-3.95

FPTVPVVES

17.13

-1.35

-4.46
P32634

VPTEPTRYN

15.36

-3.14

-6.25

EPLPPVPKA

16.79

-1.66

-4.77

NSPILPVLN

17.46

0.81

-2.30
Q06833

RRPVPRRPS

15.91

-2.10

-5.21

FPVPPSASN

17.10

-1.65

-4.76

NFPVPPSAS

17.25

-0.36

-3.47
P50101

FPGSPIDKS

14.98

-0.43

-3.54
P53118

PHDLPSHLG

12.42

-3.68

-6.79
Q12199

TPSVQPTAA

19.04

-1.20

-4.31

TTPSVQPTA

20.13

1.06

-2.05

NPNNPQCLH

20.32

0.32

-2.79
P19158

SMTPVSPLG

15.41

-0.49

-3.60

SLPDTPTMS

19.11

1.89

-1.22

TPVSPLGLD

19.63

0.83

-2.28
P38870

TPERPKRKS

11.16

-3.28

-6.39

TTPERPKRK

15.68

0.10

-3.01

PTTPERPKR

18.86

2.56

-0.55
P43638

PTNIPPPRG

10.55

-5.22

-8.33

APKLPSAFR

14.86

-0.70

-3.81

RPIPPHPDA

16.53

-1.44

-4.55
P53933

PPPIPSTQK

17.02

-0.89

-4.00

APPPLPNRQ

17.51

-2.06

-5.17

RPPPPPIPS

19.60

-2.97

-6.08
P32790

APLDPFKTG

14.09

-3.34

-6.45

LPPIKPPRP

15.02

-4.31

-7.42

PPRPTSTTS

18.19

-0.31

-3.42
P40020

LPPYLSPQN

16.00

-1.73

-4.84

PYLSPQNKD

16.60

1.29

-1.82

APSIPVEHS

16.73

-0.94

-4.05
P38238

LDPVQSPTN

19.28

1.15

-1.96

QSPTNPPYK

19.92

1.21

-1.90
P00175

RFLPNHPGG

14.95

-1.77

-4.88

TRFLPNHPG

15.75

-2.85

-5.96

LPNHPGGQD

17.38

-0.17

-3.28
Q08229

YNPTIPPRS

14.21

-3.11

-6.22

LPSTPNEDS

16.47

-0.07

-3.18

LPTPVQPGG

16.81

-2.58

-5.69
P38930

AFPDMVPKH

18.57

1.06

-2.05

FPDMVPKHP

19.01

-4.84

-7.95
Q12446

APPPPPRRG

11.30

-7.76

-10.87

LPPLPNQFA

13.06

-3.03

-6.14

IPEIPSTQS

14.21

-1.34

-4.45
P32855

PSSSPNSLG

16.08

-0.06

-3.17

NAPTLPKRK

16.47

-2.05

-5.16

SNPSSSPNS

18.89

2.33

-0.78
Q12211

RPKSGPRLD

17.54

-0.62

-3.73

KRPKSGPRL

20.17

-1.40

-4.51
Q06116

NSPELVPRS

14.80

0.56

-2.55

SPELVPRSS

18.04

-2.54

-5.65

VKPFYPVTS

19.32

0.48

-2.63
P33336

LPSHPSSNN

15.75

-1.91

-5.02

DRNLPSHPS

17.08

-0.04

-3.15

RNLPSHPSS

19.90

0.79

-2.32
P40041

IPLSPPSSS

19.43

-1.42

-4.53

KIPLSPPSS

19.52

-2.55

-5.66

PLSPPSSSN

20.07

-0.13

-3.24
P38090

SPNDPDLTA

17.95

-1.14

-4.25
Q06266

SPAFPGQLA

14.79

-0.09

-3.20

IPSSPAFPG

16.81

-1.87

-4.98

DYPTPFPSS

17.33

-0.79

-3.90
Q00916

KRPTDYPYA

14.37

0.14

-2.97

PRPPLSYKR

16.11

1.44

-1.67

PTDYPYAKR

17.34

1.87

-1.24
P07269

LPNTPDFLK

17.04

-0.94

-4.05

APDEDPNLN

18.62

-0.54

-3.65

DSGPQRPKR

19.07

2.51

-0.60
P40563

PSERPKRRA

11.24

-3.23

-6.34

PPPVPKKPS

17.94

-1.13

-4.24

NSEPPTPAG

18.14

0.88

-2.23
P10566

TRPIPAIPM

18.50

0.66

-2.45

IPAIPMDLP

19.67

-1.58

-4.69

AIPMDLPDY

20.78

0.01

-3.10
P38289

DPENPSFIN

16.73

0.73

-2.38

DVPTNDPSG

16.89

-1.07

-4.18
P47030

FPPEPSMSS

12.89

-2.32

-5.43

AFPPEPSMS

19.94

0.30

-2.81

NANNPLDKP

20.23

1.80

-1.31
P53901

LPPIPTRDD

15.27

-3.50

-6.61

PNSHPHPSG

16.63

-0.65

-3.76

LPPLPTTSN

17.56

-3.41

-6.52
P32862

VPSTPSRSN

14.50

-2.30

-5.41

SPGSTPQRS

15.10

-2.01

-5.12

MNPSNSPNS

17.30

0.94

-2.17
P39743

SNPLTSPVA

18.38

0.61

-2.50
P31374

SPERPSFRQ

11.45

-0.43

-3.54

QPRLPSTAS

13.35

-2.39

-5.50

FPNLDPTHS

15.31

-3.75

-6.86
P53169

IMPTLPPRP

18.37

-3.01

-6.12

MPTLPPRPY

20.12

-4.55

-7.66

YSPAQPSAS

20.15

1.75

-1.36
P53955

RNPIPYPID

17.95

1.55

-1.56

NPIPYPIDA

18.65

0.07

-3.04

 


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