ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-13.PDB
Scoring matrix: LSB3_2A08-13_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 18.74
Foldx random average score for Saccharomyces cerevisiae: 17.106

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 2200061
Proteins after disorder filtering: 4872
 Total fragments: 141844
Proteins after pattern filtering: 2327
 Total fragments: 18934
Proteins after MINT filtering: 74
 Total fragments: 1086


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

18.74

-0.12

0.00
Best peptides

RPYRNPRR

0.00

-8.89

-8.77
         
Interactors      
P38140

QPDLPPRK

6.94

-9.30

-9.18

MNIQPDLP

13.11

-5.09

-4.97

IPPHPYPS

13.15

-4.44

-4.32
Q06604

KPLLPTRP

6.38

-7.53

-7.41

PPPLPTRR

6.88

-8.79

-8.67

GPRMPSRG

7.46

-8.11

-7.99
P09119

MSAIPITP

12.17

-4.19

-4.07

PTTSPVKK

14.41

-3.05

-2.93

TPTTSPVK

14.78

-4.75

-4.63
P24814

NSTRPQMP

12.48

-4.85

-4.73

PPDIHPNL

13.97

-0.68

-0.56

DIHPNLGP

14.37

-2.18

-2.06
P25604

TPPLPPKP

10.23

-8.64

-8.52

APSLPPKP

10.67

-6.42

-6.30

LPPKPKSP

11.52

-6.21

-6.09
P40956

TPPLPRRR

6.84

-10.25

-10.13

PPLPRRRA

8.95

-6.82

-6.70

STPPLPRR

10.68

-7.32

-7.20
P25623

QPPLQPQS

12.62

-5.58

-5.46

EPASPSIS

12.96

-4.90

-4.78

PLQPQSKT

13.04

-4.24

-4.12
P50942

RPCPPIRR

5.50

-9.50

-9.38

KPEKPPVV

10.02

-7.27

-7.15

PPPPTSRH

10.03

-7.85

-7.73
Q04322

PPTLPPRR

6.78

-9.52

-9.40

SPPLPPRA

7.30

-10.05

-9.93

PTLPPRRI

11.42

-6.05

-5.93
P38266

PPPKPFRR

6.06

-9.42

-9.30

PPPKPFRH

6.49

-9.66

-9.54

VPILPPRN

7.34

-9.20

-9.08
P47043

PPQLPPKC

11.20

-7.21

-7.09

KPPQLPPK

12.56

-4.74

-4.62

KNKPNPPP

12.65

-2.83

-2.71
P15891

APPPPPRR

7.39

-8.45

-8.33

QPPLPSRN

7.75

-9.57

-9.45

PPPPPRRA

8.84

-8.14

-8.02
P40341

KPPLNDPS

11.02

-4.11

-3.99

PPPPPPKP

11.29

-5.78

-5.66

NDPSNPVS

11.73

-4.60

-4.48
Q12134

QPVPSPMN

14.41

-3.98

-3.86

HQPVPSPM

15.41

-2.09

-1.97

PVPSPMNS

16.10

-2.37

-2.25
P40494

DKSRPPRP

7.52

-8.20

-8.08

RPPRPPPK

8.45

-6.24

-6.12

PPRPPPKP

11.32

-5.96

-5.84
Q12200

PPSFPSRR

8.12

-7.79

-7.67

LPCPVPRS

12.16

-8.75

-8.63

PSFPSRRC

12.35

-4.52

-4.40
Q12344

SPPLPPRQ

7.04

-8.82

-8.70

SPKLPPRG

7.42

-9.07

-8.95

TSPKLPPR

14.34

-3.27

-3.15
P53189

TLQPSTIP

15.04

-3.93

-3.81

LQPSTIPQ

16.95

-0.80

-0.68
P53238

KPAGRPIP

11.35

-6.68

-6.56

RPIPPAPT

11.90

-3.48

-3.36

IPPAPTHY

13.19

-6.06

-5.94
P32660

DPTDPNRP

8.37

-5.88

-5.76

TDPNRPKV

11.58

-6.99

-6.87

DPNRPKVT

12.51

-6.02

-5.90
P33400

LPPLPVGI

12.86

-5.67

-5.55

ILPPLPVG

12.93

-3.50

-3.38

PPNAPSYQ

13.38

-3.72

-3.60
P53901

LPPIPTRD

6.29

-8.95

-8.83

QPPLPPIP

10.78

-7.15

-7.03

MRPIPPLP

10.96

-6.85

-6.73
P38739

SPFHDPIL

12.17

-3.47

-3.35

SPPNDPST

14.25

-2.26

-2.14

PFHDPILP

14.30

-3.43

-3.31
Q04749

NPVFNPRK

5.33

-7.58

-7.46

LPVLPRRI

6.69

-9.83

-9.71

PLPVLPRR

7.66

-8.93

-8.81
P04051

LPHFPKNS

13.17

-4.61

-4.49

DRSLPHFP

13.74

-5.91

-5.79

NPAMLPGS

13.98

-3.90

-3.78
P43603

RFTAPTSP

12.34

-3.49

-3.37

APTSPSTS

15.19

-3.28

-3.16
P40325

QPPRPPRP

5.94

-10.10

-9.98

QPRPPPRP

7.87

-8.92

-8.80

RPQQNPSL

8.88

-4.45

-4.33
P47129

PPLLPPRN

7.60

-9.00

-8.88

PNPPPNRS

10.75

-6.67

-6.55

RKPNPPPN

11.50

-2.79

-2.67
P40453

PPDLPIRL

7.88

-8.40

-8.28

KPPDLPIR

10.33

-4.93

-4.81

PPPLPPKI

10.52

-6.51

-6.39
P40095

PPRSPNRP

8.79

-7.20

-7.08

PVLPPPRS

10.33

-6.96

-6.84

RSPNRPTL

11.35

-4.13

-4.01
Q12168

PPPLPPRA

7.34

-8.92

-8.80

PPPVPNRP

7.66

-9.26

-9.14

PYFPQFRS

9.66

-6.35

-6.23
P36125

LPAGPQGQ

15.46

-3.52

-3.40

SNDLPAGP

16.16

-3.53

-3.41

PAGPQGQR

16.34

-1.84

-1.72
P53142

PLIEPTTT

15.11

-3.14

-3.02
P40528

LNDIPITP

13.44

-3.80

-3.68

IPITPSHD

14.09

-5.74

-5.62

PLPYPIAQ

14.68

-3.46

-3.34
P36123

TPKTPPRP

8.18

-6.63

-6.51

RPGNPLYT

8.76

-4.33

-4.21

PDHFPSRS

9.80

-5.76

-5.64
Q08412

LPTQPVRK

6.49

-8.50

-8.38

PPQLPTRT

8.29

-8.82

-8.70

ELPTQPVR

12.26

-5.06

-4.94
P32793

GPTHPSNM

14.15

-3.46

-3.34

LGHGPTHP

17.02

-3.45

-3.33
Q06409

KPRKTPRP

6.57

-9.70

-9.58

KTPRPPFP

11.64

-4.64

-4.52

FPTVPVVE

11.95

-5.78

-5.66
P32634

VPTEPTRY

8.68

-7.99

-7.87

YPLNLPIV

11.77

-4.90

-4.78

LEPLPPVP

11.95

-6.06

-5.94
Q06833

RRPVPRRP

5.48

-8.45

-8.33

RPSQPLNT

10.66

-4.47

-4.35

RPVPRRPS

11.66

-4.95

-4.83
P50101

FPGSPIDK

14.77

-3.22

-3.10

VFPGSPID

15.66

-3.41

-3.29
P53118

NPHDLPSH

13.84

-2.01

-1.89

PHDLPSHL

16.07

-4.13

-4.01

ENPHDLPS

16.44

0.60

0.72
Q12199

APATPPRH

8.44

-7.93

-7.81

NNPNNPQC

12.35

-2.01

-1.89

TPSVQPTA

13.48

-4.92

-4.80
P19158

LPDTPTMS

12.26

-5.79

-5.67

DPSLPDTP

13.72

-5.21

-5.09

GEYDPSLP

14.81

-4.00

-3.88
P38870

TPERPKRK

6.27

-10.08

-9.96

TPTTPERP

9.17

-7.58

-7.46

TTPERPKR

12.97

-4.51

-4.39
P43638

RPIPPHPD

12.16

-3.02

-2.90

IPPHPDAP

12.81

-5.27

-5.15

APKLPSAF

13.49

-4.46

-4.34
P53933

PPPLPNRQ

7.78

-8.85

-8.73

RPPPPPIP

8.49

-6.22

-6.10

RRRPPPPP

12.04

-3.49

-3.37
P32790

PPIKPPRP

6.45

-9.24

-9.12

PPAMPARP

7.30

-9.89

-9.77

KPPRPTST

11.60

-5.32

-5.20
P40020

EPTSPTRQ

8.75

-6.75

-6.63

LPPLPFPL

12.27

-5.80

-5.68

RPPPLTPE

12.56

-1.76

-1.64
P38238

SPTNPPYK

10.77

-4.81

-4.69

LDPVQSPT

13.63

-3.93

-3.81

QSPTNPPY

14.28

-2.59

-2.47
P00175

RFLPNHPG

11.02

-2.80

-2.68

TRFLPNHP

14.60

-5.82

-5.70

LPNHPGGQ

14.83

-4.32

-4.20
Q08229

NPTIPPRS

6.64

-8.31

-8.19

NDYNPTIP

11.58

-3.56

-3.44

RPLPSTPN

13.75

-1.77

-1.65
P38930

FPDMVPKH

13.07

-7.68

-7.56

PDMVPKHP

14.46

-5.95

-5.83

AFPDMVPK

15.26

-1.74

-1.62
Q12446

LPQLPNRN

7.25

-8.87

-8.75

APPPPPRR

7.39

-8.45

-8.33

APPPPPRA

8.33

-7.20

-7.08
P32855

APTLPKRK

7.45

-9.36

-9.24

NAPTLPKR

13.64

-4.25

-4.13

NPSSSPNS

15.81

-1.46

-1.34
Q12211

RPKSGPRL

7.05

-7.11

-6.99

MQYNPPNP

11.70

-4.01

-3.89

KRPKSGPR

14.55

-2.14

-2.02
Q06116

SPELVPRS

11.43

-7.62

-7.50

NGVKPFYP

12.92

-3.60

-3.48

KPFYPVTS

13.06

-4.12

-4.00
P33336

LPSHPSSN

13.64

-4.31

-4.19

TCDPEDYP

15.31

-2.22

-2.10

DRNLPSHP

15.55

-4.13

-4.01
P40041

GRTLPPVP

13.31

-5.13

-5.01

IPLSPPSS

13.58

-4.62

-4.50

KIPLSPPS

15.12

-3.89

-3.77
P38090

SPNDPDLT

15.07

-3.95

-3.83

VCSPNDPD

16.29

-1.28

-1.16
Q06266

FPSSPYRT

8.24

-7.59

-7.47

IPSSPAFP

12.27

-5.51

-5.39

RTVDPYSP

13.24

-1.88

-1.76
Q00916

RLFKPRPP

9.70

-4.95

-4.83

FKPRPPLS

12.24

-5.66

-5.54

KPRPPLSY

13.16

-4.10

-3.98
P07269

SDSGPQRP

10.85

-5.28

-5.16

SGPQRPKR

13.01

-4.58

-4.46

LPNTPDFL

13.36

-4.15

-4.03
P40563

TPKVPERP

7.64

-8.84

-8.72

PSERPKRR

7.87

-7.56

-7.44

PPPVPKKP

10.86

-6.05

-5.93
P10566

TRPIPAIP

12.27

-5.46

-5.34

RPIPAIPM

12.49

-3.90

-3.78

IPAIPMDL

13.07

-5.19

-5.07
P38289

DPENPSFI

12.55

-4.40

-4.28

EDPENPSF

12.78

-2.99

-2.87

VPTNDPSG

14.62

-3.03

-2.91
P47030

FPPEPSMS

11.80

-6.04

-5.92

AFPPEPSM

15.09

-1.91

-1.79

ANNPLDKP

15.56

-2.82

-2.70
P32863

LPDRPPNG

11.23

-6.14

-6.02

PDRPPNGI

16.33

-1.38

-1.26
P32862

VPSTPSRS

9.40

-7.88

-7.76

RPPNPPAN

10.13

-3.90

-3.78

FNYRPPNP

11.84

-4.49

-4.37
P39743

NPLTSPVA

14.98

-4.02

-3.90

YSNPLTSP

17.09

-2.14

-2.02
P31374

NNISPERP

10.12

-5.98

-5.86

RKTKPPPP

10.51

-5.87

-5.75

SPERPSFR

10.64

-6.33

-6.21
P53169

MPTLPPRP

4.81

-10.94

-10.82

VPIMPTLP

12.56

-7.43

-7.31

ANSVPIMP

13.43

-4.55

-4.43
Q07660

SAFKPIGP

15.31

-3.95

-3.83
P53955

RNPIPYPI

11.48

-3.17

-3.05

QRNPIPYP

15.30

-1.04

-0.92

NQNDPRSP

16.10

-2.99

-2.87

 


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