ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-11.PDB
Scoring matrix: LSB3_2A08-11_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.46
Foldx random average score for Saccharomyces cerevisiae: 12.065

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1951882
Proteins after disorder filtering: 4929
 Total fragments: 130029
Proteins after pattern filtering: 2305
 Total fragments: 13588
Proteins after MINT filtering: 74
 Total fragments: 841


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.46

-1.34

0.00
Best peptides

EDWRRPY

0.00

-3.31

-1.97
         
Interactors      
P38140

NIPPHPY

4.04

-1.63

-0.29

QPDLPPR

6.24

-8.45

-7.11

NIQPDLP

10.35

-2.19

-0.85
Q06604

PPLPTRR

6.97

-9.10

-7.76

GPRMPSR

7.35

-8.10

-6.76

KPLLPTR

7.81

-7.21

-5.87
P09119

TPTTSPV

10.09

-2.45

-1.11

QVPLTPT

10.85

-2.72

-1.38

LTPTTSP

11.25

-2.33

-0.99
P24814

PPDIHPN

7.98

-2.94

-1.60

IHPNLGP

9.86

-2.96

-1.62

TRPQMPS

9.94

-3.04

-1.70
P25604

PPKPKSP

8.75

-4.83

-3.49

PKPKSPH

8.87

-3.60

-2.26

PLPPKPK

9.17

-5.11

-3.77
P40956

PPLPRRR

4.44

-9.37

-8.03

STPPLPR

6.92

-6.81

-5.47

TPPLPRR

7.78

-8.60

-7.26
P25623

QPPLQPQ

7.83

-3.96

-2.62

EVPPSTP

8.24

-3.08

-1.74

LPPHATP

9.85

-4.86

-3.52
P50942

PPPPTSR

6.56

-7.45

-6.11

PCPPIRR

7.38

-7.19

-5.85

RPCPPIR

7.47

-8.51

-7.17
Q04322

SPPLPPR

7.74

-8.11

-6.77

PPTLPPR

8.03

-8.62

-7.28

PTLPPRR

8.77

-7.48

-6.14
P38266

QPPPKPF

4.99

-5.84

-4.50

MPPPKPF

5.40

-5.74

-4.40

QPPVPVR

5.55

-8.21

-6.87
P47043

KPPQLPP

7.51

-6.24

-4.90

KNKPNPP

8.93

-4.07

-2.73

SDPTSPQ

9.70

-1.40

-0.06
P15891

QPPLPSR

6.17

-8.33

-6.99

APPPPPR

6.88

-8.34

-7.00

TPEKKPK

7.04

-4.97

-3.63
P40341

KPPLNDP

7.75

-4.54

-3.20

PPPPKPP

8.20

-4.50

-3.16

NDPSNPV

8.83

-1.46

-0.12
Q12134

QPVPSPM

7.80

-3.71

-2.37

HQPVPSP

11.62

-3.33

-1.99
P40494

QPPNMMP

6.90

-5.23

-3.89

RPPPKPL

7.76

-4.27

-2.93

PPNMMPV

8.19

-6.38

-5.04
Q12200

LPCPVPR

7.03

-8.40

-7.06

PPSFPSR

7.21

-7.89

-6.55

PSFPSRR

7.70

-5.63

-4.29
Q12344

SPPLPPR

7.74

-8.11

-6.77

SPKLPPR

8.00

-7.84

-6.50

TSPKLPP

9.80

-4.18

-2.84
P53189

QPSTIPQ

9.05

-3.90

-2.56
P53238

PPAPTHY

6.84

-4.34

-3.00

KPAGRPI

8.75

-3.78

-2.44

QKPAGRP

10.57

-2.83

-1.49
P32660

TDPNRPK

7.09

-3.42

-2.08

HAPMSPF

7.57

-3.26

-1.92

DPTDPNR

9.19

-6.34

-5.00
P33400

PPNAPSY

7.89

-5.34

-4.00

QPPNAPS

9.05

-3.93

-2.59

SPQILPP

9.13

-4.81

-3.47
P53901

LPPIPTR

6.67

-8.74

-7.40

DPIILPP

8.65

-5.14

-3.80

SPNSHPH

8.83

-1.43

-0.09
P38739

HDPILPR

3.84

-6.99

-5.65

ASPFHDP

9.39

-0.81

0.53

SPFHDPI

9.90

-2.73

-1.39
Q04749

NPVFNPR

4.07

-5.93

-4.59

PLPVLPR

6.31

-9.11

-7.77

LPVLPRR

8.18

-8.73

-7.39
P04051

RSLPHFP

9.51

-0.73

0.61

NPAMLPG

9.89

-5.72

-4.38

VNPAMLP

10.43

-3.98

-2.64
P43603

FTAPTSP

11.75

-2.50

-1.16

TAPTSPS

11.83

-1.11

0.23
P40325

QPPRPPR

4.09

-9.10

-7.76

QPRPPPR

5.58

-8.07

-6.73

RPPPRPQ

7.31

-4.87

-3.53
P47129

PPLLPPR

7.83

-8.47

-7.13

LPNRKPN

8.68

-4.98

-3.64

NRKPNPP

9.38

-2.73

-1.39
P40453

PPDLPIR

8.42

-8.30

-6.96

IPPPLPP

8.44

-6.23

-4.89

PPSWKPP

8.60

-3.99

-2.65
P40095

LPPPRSP

7.58

-5.30

-3.96

PVLPPPR

7.99

-7.71

-6.37

RIPVLPP

8.25

-5.78

-4.44
Q12168

PYFPQFR

6.81

-5.74

-4.40

PPPVPNR

7.00

-9.53

-8.19

PPPLPPR

7.41

-8.90

-7.56
P36125

NDLPAGP

9.71

-2.93

-1.59

PAGPQGQ

11.39

-2.23

-0.89
P32793

HGPTHPS

10.29

0.05

1.39

PTHPSNM

11.05

-2.16

-0.82
P40528

IPITPSH

10.27

-5.04

-3.70

NDIPITP

10.48

-2.27

-0.93

DIPITPS

10.87

-3.31

-1.97
P36123

RPGNPLY

7.09

-4.82

-3.48

PDHFPSR

7.15

-6.29

-4.95

TPKTPPR

7.22

-7.32

-5.98
Q08412

LPTQPVR

7.45

-9.30

-7.96

ELPTQPV

8.14

-4.07

-2.73

PPQLPTR

8.88

-9.04

-7.70
Q06697

GPRKDPI

8.93

-3.16

-1.82

GGPRKDP

10.29

-2.99

-1.65
Q06409

KPRKTPR

4.55

-8.20

-6.86

PRNPDPY

7.01

-1.85

-0.51

KTPRPPF

7.93

-6.09

-4.75
P32634

PTEPTRY

7.76

-1.81

-0.47

VPKAPSR

7.82

-7.49

-6.15

VPTEPTR

8.11

-6.41

-5.07
Q06833

RPVPRRP

7.36

-5.03

-3.69

PVPRRPS

7.97

-5.18

-3.84

RRPSQPL

10.07

-1.68

-0.34
P53118

ENPHDLP

9.14

-2.05

-0.71

NPHDLPS

11.62

-3.52

-2.18
Q12199

APATPPR

7.25

-7.97

-6.63

TPSVQPT

9.54

-2.98

-1.64

QPTAAPA

9.79

-3.97

-2.63
P19158

MTPVSPL

8.63

-3.10

-1.76

EYDPSLP

9.09

-1.90

-0.56

PVSPLGL

10.60

-5.16

-3.82
P38870

TPERPKR

6.47

-7.92

-6.58

TTPERPK

8.06

-4.30

-2.96

TPTTPER

9.02

-7.12

-5.78
P43638

IPPTDAP

8.76

-3.27

-1.93

PDAPKLP

8.91

-3.22

-1.88

SVPTNIP

9.10

-3.23

-1.89
P53933

PPPLPNR

7.99

-9.42

-8.08

PPLPNRQ

8.91

-4.58

-3.24

LPMELPH

9.12

-4.99

-3.65
P50101

TVFPGSP

11.24

-2.99

-1.65

VFPGSPI

11.78

-0.93

0.41
P40020

EPTSPTR

7.12

-6.86

-5.52

PESPLNR

7.75

-7.24

-5.90

PLPFPLY

7.99

-5.56

-4.22
P38238

SPTNPPY

7.77

-4.44

-3.10

LDPVQSP

7.81

-2.96

-1.62

QSPTNPP

7.84

-3.13

-1.79
P00175

RFLPNHP

8.86

-2.89

-1.55

CPPYAPG

9.87

-4.16

-2.82

FLPNHPG

10.17

-1.67

-0.33
Q08229

NPTIPPR

6.63

-8.69

-7.35

RPLPSTP

9.21

-3.29

-1.95

PTPVQPG

9.99

-2.77

-1.43
P38930

MVPKHPT

7.11

-2.92

-1.58

FPDMVPK

9.26

-6.79

-5.45

DMVPKHP

10.10

-3.51

-2.17
Q12446

QPQSNPF

5.83

-4.97

-3.63

PPPRRGP

6.27

-6.53

-5.19

PPLPNQF

6.59

-6.00

-4.66
P32855

APTLPKR

8.45

-7.79

-6.45

PTLPKRK

9.68

-3.49

-2.15

NAPTLPK

10.31

-3.51

-2.17
Q12211

PLPKEPR

4.97

-8.42

-7.08

RPKSGPR

6.67

-7.23

-5.89

KRPKSGP

8.68

-3.27

-1.93
Q06116

SPELVPR

7.56

-8.19

-6.85

SEPVEPF

7.86

-3.23

-1.89

EPVEPFS

10.70

-4.10

-2.76
P33336

CDPEDYP

8.73

-1.20

0.14

NLPSHPS

10.87

-0.87

0.47

RNLPSHP

10.87

-2.86

-1.52
P40041

KIPLSPP

9.00

-3.14

-1.80

RTLPPVP

11.99

-3.54

-2.20
P38090

VCSPNDP

9.60

-3.64

-2.30
Q06266

QFPSSPY

5.44

-1.78

-0.44

VDPYSPP

8.49

-1.85

-0.51

FPSSPYR

8.71

-7.13

-5.79
Q00916

PRPPLSY

7.03

-4.83

-3.49

LFKPRPP

8.77

-3.46

-2.12

KRPTDYP

10.02

-1.62

-0.28
P07269

GPQRPKR

7.45

-7.55

-6.21

SGPQRPK

8.72

-3.30

-1.96

LPNTPDF

9.84

-5.72

-4.38
P40563

TPNVPTR

7.84

-8.48

-7.14

TPKVPER

8.21

-7.50

-6.16

EVTPKVP

8.22

-2.97

-1.63
P10566

PMDLPDY

8.71

-4.55

-3.21

AIPMDLP

8.83

-3.63

-2.29

RPIPAIP

9.40

-4.54

-3.20
P38289

EDPENPS

6.60

-2.75

-1.41

DVPTNDP

8.87

-3.29

-1.95

DPENPSF

9.84

-5.10

-3.76
P47030

TKPPRAP

9.61

-3.59

-2.25

FPPEPSM

10.72

-4.65

-3.31

AFPPEPS

10.84

-1.76

-0.42
P32790

PPIKPPR

6.07

-9.60

-8.26

LPPIKPP

7.25

-4.86

-3.52

PPAMPAR

7.25

-8.63

-7.29
P32863

LPDRPPN

10.70

-6.00

-4.66
P32862

VPSTPSR

7.56

-6.53

-5.19

NPPANNP

8.49

-3.97

-2.63

YRPPNPP

9.30

-3.45

-2.11
P39743

TIPEDNP

9.69

-1.95

-0.61

NPLTSPV

9.83

-2.52

-1.18
P31374

PERPSFR

7.27

-7.10

-5.76

PPPPLDF

7.81

-7.24

-5.90

SPERPSF

8.46

-6.57

-5.23
P53169

TLPPRPY

4.92

-5.51

-4.17

MPTLPPR

6.91

-8.71

-7.37

IMPTLPP

9.12

-4.15

-2.81
Q07660

AFKPIGP

11.17

-2.57

-1.23
P53955

NDPRSPL

7.72

-2.82

-1.48

QNDPRSP

8.37

-3.25

-1.91

RNPIPYP

11.28

-5.18

-3.84

 


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