ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_2A08-10.PDB
Scoring matrix: LSB3_2A08-10_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.73
Foldx random average score for Saccharomyces cerevisiae: 19.561

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 2086696
Proteins after disorder filtering: 4882
 Total fragments: 187391
Proteins after pattern filtering: 2336
 Total fragments: 20834
Proteins after MINT filtering: 74
 Total fragments: 1124


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.73

0.75

0.00
Best peptides

RPWRIPRR

0.00

0.92

0.17
         
Interactors      
P38140

QPDLPPRK

6.53

-6.26

-7.01

MNIQPDLP

9.27

-2.19

-2.94

PDLPPRKI

11.31

-1.84

-2.59
Q06604

KPLLPTRP

5.40

-5.95

-6.70

PPPLPTRR

6.59

-6.15

-6.90

LPTRPNKA

7.23

-4.77

-5.52
P09119

MSAIPITP

10.90

-1.08

-1.83

TPTTSPVK

11.10

-1.36

-2.11

PLTPTTSP

11.54

3.22

2.47
P24814

HPNLGPQL

7.78

-3.64

-4.39

NSTRPQMP

8.80

-2.74

-3.49

HPPDIHPN

11.71

1.00

0.25
P25604

TPPLPPKP

8.09

-4.01

-4.76

PKPKSPHL

8.17

-1.75

-2.50

KPKSPHLK

8.20

-3.78

-4.53
P40956

NPKNVPFP

4.97

2.36

1.61

TPPLPRRR

7.13

-6.37

-7.12

PKNVPFPF

12.97

-0.88

-1.63
P25623

LPKTVPIS

7.56

0.57

-0.18

TPPLPPHA

8.00

-3.41

-4.16

PPHATPKN

9.28

1.25

0.50
P50942

RPCPPIRR

3.86

-6.25

-7.00

PCPPIRRK

7.09

-0.15

-0.90

PPPPTSRH

7.18

-2.55

-3.30
Q04322

PPTLPPRR

6.27

-6.88

-7.63

SPPLPPRA

7.37

-5.74

-6.49

TPSKSPTS

9.36

-2.00

-2.75
P38266

KPPVVPKK

5.14

0.16

-0.59

PPPKPFRR

5.86

-7.32

-8.07

PPPKPFRH

6.02

-7.08

-7.83
P47043

PPQLPPKC

8.25

-3.54

-4.29

KPNPPPGS

9.33

-3.05

-3.80

ESKPPQLP

10.50

-2.40

-3.15
P15891

APPPPPRR

6.67

-6.35

-7.10

PPPPPRRA

7.39

-5.14

-5.89

QPPLPSRN

7.50

-5.63

-6.38
P40341

PPPKPPLN

7.51

-4.95

-5.70

PPPPPPKP

7.89

-4.46

-5.21

PPKPPLND

9.42

-2.80

-3.55
Q12134

QPVPSPMN

7.81

-2.72

-3.47

THQPVPSP

10.15

0.93

0.18

HQPVPSPM

13.93

-0.17

-0.92
P40494

DKSRPPRP

6.55

-5.09

-5.84

KPTLIPDN

6.68

0.63

-0.12

RPPRPPPK

7.44

-5.07

-5.82
Q12200

LPCPVPRS

4.18

-2.32

-3.07

PPSFPSRR

6.80

-5.95

-6.70

PSFPSRRC

9.14

-2.34

-3.09
Q12344

SPKLPPRG

6.99

-5.30

-6.05

SPPLPPRQ

7.30

-5.80

-6.55

PPLPPRQN

9.56

-3.37

-4.12
P53189

TLQPSTIP

9.85

-1.61

-2.36

LQPSTIPQ

14.35

2.92

2.17
P53238

IPPAPTHY

8.38

-2.55

-3.30

RPIPPAPT

9.11

-2.71

-3.46

PPAPTHYN

9.64

1.78

1.03
P32660

DPTDPNRP

8.44

-4.20

-4.95

DPNRPKVT

9.04

-2.64

-3.39

HYPPGYDP

9.96

-1.25

-2.00
P33400

PPLPVGIS

6.85

0.91

0.16

QPPNAPSY

8.70

-2.09

-2.84

PQILPPLP

9.16

-1.77

-2.52
P53901

LPPIPTRD

5.93

-5.88

-6.63

MRPIPPLP

6.88

-3.98

-4.73

SPKLPPLP

8.12

-3.34

-4.09
P38739

PFHDPILP

10.26

-2.32

-3.07

PNDPSTLA

10.38

-0.80

-1.55

FHDPILPR

10.62

1.43

0.68
Q04749

LPVLPRRI

6.43

-6.53

-7.28

NPRKPTLS

7.08

-3.93

-4.68

NPVFNPRK

9.30

0.54

-0.21
P04051

DRSLPHFP

8.70

-1.54

-2.29

LPHFPKNS

9.31

-2.63

-3.38

SVNPAMLP

10.09

-2.64

-3.39
P43603

RFTAPTSP

8.80

-1.63

-2.38

APTSPSTS

11.64

-0.92

-1.67

PTSPSTSS

14.21

-0.36

-1.11
P40325

QPPRPPRP

5.58

-6.80

-7.55

RPPRPAAN

6.49

-3.29

-4.04

QPRPPPRP

6.51

-4.86

-5.61
P47129

PPLLPPRN

6.67

-6.40

-7.15

KPNPPPNR

7.69

-3.19

-3.94

PNPPPNRS

9.92

-2.94

-3.69
P40453

PPPPVSMP

6.22

-0.57

-1.32

PPDLPIRL

7.25

-5.92

-6.67

VPEPPSWK

8.22

-3.59

-4.34
P40095

SPNRPTLS

7.50

-3.26

-4.01

PPPRSPNR

8.04

-2.96

-3.71

PPRSPNRP

8.58

-3.77

-4.52
Q12168

IPPPVPNR

6.95

0.81

0.06

PPPLPPRA

6.96

-6.44

-7.19

VQHPVPKP

7.28

-0.37

-1.12
P36125

DLPAGPQG

10.62

-1.61

-2.36

LPAGPQGQ

12.57

-2.03

-2.78

NDLPAGPQ

12.96

0.59

-0.16
P53142

PLIEPTTT

11.56

-1.47

-2.22
P40528

IPITPSHD

9.92

-2.61

-3.36

LNDIPITP

11.00

-1.16

-1.91

NDIPITPS

12.08

1.81

1.06
P36123

RPGNPLYT

6.37

-3.53

-4.28

TPKTPPRP

8.33

-5.62

-6.37

TPPRPKTI

9.52

-3.13

-3.88
Q08412

LPTQPVRK

5.73

-6.31

-7.06

PPQLPTRT

6.90

-5.45

-6.20

LPPEPLDT

9.45

-2.44

-3.19
P32793

GPTHPSNM

10.28

-1.53

-2.28

LGHGPTHP

11.19

-0.29

-1.04

PTHPSNMS

12.98

-1.33

-2.08
Q06409

KPRKTPRP

4.78

-3.75

-4.50

FPTVPVVE

8.77

-2.99

-3.74

KTPRPPFP

9.16

-3.89

-4.64
P32634

VPTEPTRY

6.47

-5.79

-6.54

PLPPVPKA

8.22

1.36

0.61

NLPIVPNP

8.40

2.71

1.96
Q06833

RRPVPRRP

4.69

-4.11

-4.86

RPSQPLNT

6.48

-2.71

-3.46

VPRRPSQP

8.01

-3.49

-4.24
P50101

PGSPIDKS

9.88

2.27

1.52

FPGSPIDK

10.07

0.00

-0.75

VFPGSPID

11.19

-0.52

-1.27
P53118

PHDLPSHL

10.36

-1.15

-1.90
Q12199

APATPPRH

9.09

-5.32

-6.07

QPTAAPAT

9.47

-2.01

-2.76

NPNNPQCL

10.18

-1.09

-1.84
P19158

LPDTPTMS

9.17

-4.73

-5.48

DPSLPDTP

10.83

-2.20

-2.95

GEYDPSLP

10.99

-0.59

-1.34
P38870

TPERPKRK

5.92

-6.11

-6.86

TPKPPPND

9.18

-2.76

-3.51

TPTTPERP

9.29

-5.78

-6.53
P43638

GRPIPPHP

7.95

-2.15

-2.90

PKLPSAFR

8.60

-1.83

-2.58

RPIPPHPD

9.48

-2.52

-3.27
P53933

RPPPPPIP

5.03

-4.78

-5.53

PPPLPNRQ

7.98

-5.88

-6.63

PPPPIPST

8.05

1.75

1.00
P32790

PPIKPPRP

5.50

-6.91

-7.66

PPAMPARP

6.81

-6.74

-7.49

KPPRPTST

7.85

-3.48

-4.23
P40020

NPHSIPFS

6.30

0.45

-0.30

EPTSPTRQ

7.67

-4.64

-5.39

SRVLPPLP

8.55

-2.27

-3.02
P38238

SPTNPPYK

8.62

-2.40

-3.15

DPVQSPTN

9.85

-0.56

-1.31

SLDPVQSP

10.94

1.24

0.49
P00175

TRFLPNHP

8.70

-1.28

-2.03

CPPYAPGE

9.48

-2.21

-2.96

PNHPGGQD

10.11

-1.08

-1.83
Q08229

NPTIPPRS

5.84

-6.02

-6.77

RPLPSTPN

8.92

-1.84

-2.59

PVQPGGHY

9.45

-2.75

-3.50
P38930

FPDMVPKH

4.59

-0.93

-1.68

PDMVPKHP

11.14

-1.30

-2.05
Q12446

FPFPVPQQ

5.85

0.91

0.16

APPPPPRR

6.67

-6.35

-7.10

PPRRGPAP

6.83

-4.36

-5.11
P32855

APTLPKRK

7.29

-5.92

-6.67

NPSSSPNS

10.20

-0.10

-0.85

TNNAPTLP

10.98

-1.06

-1.81
Q12211

RPKSGPRL

2.93

-6.86

-7.61

MQYNPPNP

9.27

-1.04

-1.79

KRPKSGPR

10.61

-1.01

-1.76
Q06116

SPELVPRS

5.57

-1.08

-1.83

PFYPVTSE

9.23

0.95

0.20

KPFYPVTS

9.50

-2.19

-2.94
P33336

DRNLPSHP

8.51

-1.34

-2.09

LPSHPSSN

9.96

-3.05

-3.80

RNLPSHPS

11.67

0.01

-0.74
P40041

GRTLPPVP

9.75

-1.70

-2.45

IPLSPPSS

10.67

-1.89

-2.64

PLSPPSSS

12.07

-1.31

-2.06
P38090

SPNDPDLT

10.11

-2.30

-3.05

IVCSPNDP

14.48

-0.06

-0.81

VCSPNDPD

18.20

6.12

5.37
Q06266

FPSSPYRT

6.84

-5.22

-5.97

IPSSPAFP

8.58

-2.62

-3.37

PAFPGQLA

9.45

-2.68

-3.43
Q00916

FKPRPPLS

6.92

-3.86

-4.61

KPRPPLSY

8.81

-2.26

-3.01

YKRPTDYP

9.70

0.56

-0.19
P07269

LPNTPDFL

9.67

-3.93

-4.68

ELPNTPDF

11.84

4.28

3.53

SDSGPQRP

12.26

-2.13

-2.88
P40563

APPPVPKK

6.38

0.82

0.07

RRAPPPVP

6.55

-2.97

-3.72

TPKVPERP

7.16

-6.32

-7.07
P10566

RPIPAIPM

7.47

-2.36

-3.11

TRPIPAIP

8.53

-2.27

-3.02

PIPAIPMD

9.41

0.57

-0.18
P38289

DPENPSFI

8.43

-1.85

-2.60

PENPSFIN

10.04

-1.81

-2.56

YDVPTNDP

12.80

4.65

3.90
P47030

FPPEPSMS

7.19

-4.32

-5.07

PPEPSMSS

10.42

-1.43

-2.18

DEAFPPEP

12.32

0.13

-0.62
P32863

LPDRPPNG

7.42

-4.18

-4.93

PDRPPNGI

14.29

-1.47

-2.22
P32862

RPPNPPAN

7.28

-3.40

-4.15

FNYRPPNP

8.55

-2.26

-3.01

VPSTPSRS

9.21

-5.61

-6.36
P39743

NPLTSPVA

11.10

-0.87

-1.62

SNPLTSPV

15.08

4.90

4.15

ATIPEDNP

15.58

2.00

1.25
P31374

SPERPSFR

6.88

-3.76

-4.51

PERPSFRQ

8.61

-4.19

-4.94

RKTKPPPP

8.71

-3.93

-4.68
P53169

MPTLPPRP

5.30

-6.72

-7.47

VPIMPTLP

7.40

-4.69

-5.44

ANSVPIMP

10.55

-2.30

-3.05
Q07660

SAFKPIGP

12.44

-1.34

-2.09
P53955

QRNPIPYP

6.79

0.76

0.01

RNPIPYPI

10.92

-1.34

-2.09

NQNDPRSP

11.88

1.02

0.27

 


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