ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1SSH-6.PDB
Scoring matrix: LSB3_1SSH-6_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.29
Foldx random average score for Saccharomyces cerevisiae: 17.679

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 2085278
Proteins after disorder filtering: 4687
 Total fragments: 170624
Proteins after pattern filtering: 2327
 Total fragments: 25160
Proteins after MINT filtering: 74
 Total fragments: 1383


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.29

-0.49

0.00
Best peptides

RPRRPRRPPR

0.00

-6.76

-6.27
         
Interactors      
P38140

MNIQPDLPPR

5.39

-6.38

-5.89

QPDLPPRKIM

5.88

-3.97

-3.48

PDLPPRKIMI

6.98

-6.44

-5.95
Q06604

GPRMPSRGRP

4.42

-5.25

-4.76

KPLLPTRPNK

5.59

-5.18

-4.69

NEEKPLLPTR

5.86

-6.76

-6.27
P09119

VPLTPTTSPV

8.81

-3.83

-3.34

SAQVPLTPTT

10.13

-3.73

-3.24

PTTSPVKKSY

11.01

-2.31

-1.82
P24814

RLHPPDIHPN

4.87

-5.57

-5.08

PDIHPNLGPQ

8.10

-2.50

-2.01

NRLHPPDIHP

8.97

-4.63

-4.14
P25604

LPPKPKSPHL

6.31

-6.26

-5.77

QDQAPSLPPK

6.52

-4.75

-4.26

EQNTPPLPPK

6.62

-4.79

-4.30
P40956

TPPLPRRRAT

6.82

-6.30

-5.81

RFWNPKNVPF

7.46

-5.13

-4.64

PPLPRRRATT

7.65

0.91

1.40
P25623

ASDTPPLPPH

7.30

-3.93

-3.44

LPVEPASPSI

7.63

-5.02

-4.53

PPLPPHATPK

8.35

-6.01

-5.52
P50942

RPCPPIRRKS

3.31

-7.50

-7.01

LPPPPPTSRH

6.01

-7.61

-7.12

ASTKPEKPPV

7.37

-5.07

-4.58
Q04322

SSTPPTLPPR

7.35

-4.61

-4.12

GNATPSKSPT

8.65

-3.48

-2.99

NDQAPLDRPQ

9.31

-3.14

-2.65
P38266

QPLPPPRGQV

4.63

-7.21

-6.72

NFLPPPKPFR

4.66

-5.97

-5.48

NFQPPPKPFR

4.67

-5.97

-5.48
P47043

LESKPPQLPP

7.16

-4.84

-4.35

ESKPPQLPPK

7.35

-5.09

-4.60

KKNKPNPPPG

7.77

-4.19

-3.70
P15891

APPPPPRRAT

4.79

-7.66

-7.17

PPPPPRRATP

5.46

-8.31

-7.82

RRATPEKKPK

5.65

-4.55

-4.06
P40341

PPPPPPKPPL

5.88

-7.03

-6.54

RNIPPPPPPP

6.08

-5.51

-5.02

PPPKPPLNDP

6.64

-6.87

-6.38
Q12134

QPVPSPMNSQ

9.19

-3.83

-3.34

HQPVPSPMNS

10.43

-3.84

-3.35

STHQPVPSPM

12.18

-2.61

-2.12
P40494

DKSRPPRPPP

4.48

-6.29

-5.80

PPRPPPKPLH

4.69

-7.58

-7.09

RPPRPPPKPL

5.47

-6.83

-6.34
Q12200

EVCPPSFPSR

7.33

-4.84

-4.35

PHLKPLKDGV

8.52

-4.97

-4.48

QESCPHLKPL

8.97

-5.93

-5.44
Q12344

SPKLPPRGKQ

7.48

-6.47

-5.98

TSTSPKLPPR

7.82

-2.47

-1.98

PPLPPRQNVA

7.92

-5.66

-5.17
P53189

STLQPSTIPQ

11.98

-2.50

-2.01

TSTLQPSTIP

17.04

4.10

4.59
P53238

RPIPPAPTHY

6.44

-5.93

-5.44

IPPAPTHYNN

9.00

-4.91

-4.42

GRPIPPAPTH

9.24

-4.84

-4.35
P32660

DPTDPNRPKV

7.17

-5.83

-5.34

FDHYPPGYDP

8.31

-4.74

-4.25

DHYPPGYDPT

9.16

-3.19

-2.70
P33400

PPNAPSYQSV

8.35

-4.68

-4.19

PQILPPLPVG

9.11

-3.76

-3.27

SYVQPPNAPS

9.55

-5.57

-5.08
P53901

LPPIPTRDDM

6.18

-6.71

-6.22

RPIPPLPTES

6.47

-5.43

-4.94

NYNQPPLPPI

6.57

-5.02

-4.53
P38739

TLASPFHDPI

9.25

-2.63

-2.14

PPNDPSTLAS

10.13

-3.91

-3.42

TAGSPPNDPS

11.19

-2.08

-1.59
Q04749

LPVLPRRIST

5.61

-5.33

-4.84

NPRKPTLSTD

6.00

-5.48

-4.99

NPVFNPRKPT

7.21

1.11

1.60
P04051

LPHFPKNSKT

6.27

-5.80

-5.31

DRSLPHFPKN

9.57

-3.77

-3.28

FQDRSLPHFP

11.54

-2.02

-1.53
P43603

RFTAPTSPST

7.52

-4.32

-3.83

APTSPSTSSP

9.55

-3.17

-2.68

GRFTAPTSPS

11.97

-2.75

-2.26
P40325

QPRPPPRPQQ

3.42

-8.21

-7.72

QPPRPPRPAA

3.77

-7.58

-7.09

RPPRPAANLA

6.91

-5.03

-4.54
P47129

PNPPPNRSQR

6.21

-6.00

-5.51

KPNPPPNRSQ

6.25

-5.65

-5.16

TSGPPLLPPR

6.91

-4.75

-4.26
P40453

RKRPPPPPPV

5.77

-6.02

-5.53

MPTTPEIPPP

5.89

-6.49

-6.00

PEIPPPLPPK

6.09

-7.53

-7.04
P40095

PVLPPPRSPN

6.44

-6.68

-6.19

PPRSPNRPTL

6.87

-5.95

-5.46

VLPPPRSPNR

7.17

-4.55

-4.06
Q12168

NRGPPPLPPR

4.73

-6.46

-5.97

PPPVPNRPGG

6.04

-7.66

-7.17

PPPLPPRANV

7.47

-6.13

-5.64
P36125

LPAGPQGQRR

9.74

-5.55

-5.06

NDLPAGPQGQ

12.38

-3.88

-3.39

SNDLPAGPQG

12.48

-2.61

-2.12
P53142

PLIEPTTTNS

9.68

-3.01

-2.52
P40528

IPITPSHDNN

7.82

-5.24

-4.75

LNDIPITPSH

8.29

-3.20

-2.71

PLPYPIAQVG

10.08

-2.52

-2.03
P36123

TPKTPPRPKT

5.42

-6.91

-6.42

PDHFPSRSQP

5.75

-5.95

-5.46

LYTTPKTPPR

6.39

-4.17

-3.68
Q08412

EDVPPQLPTR

6.18

-7.00

-6.51

PPQLPTRTKS

7.58

-5.32

-4.83

DEDVPPQLPT

8.20

-6.40

-5.91
Q06697

SSGGPRKDPI

10.48

-3.70

-3.21

GSSGGPRKDP

12.98

-3.19

-2.70
P40041

PLSPPSSSNM

9.00

-3.98

-3.49

IPLSPPSSSN

9.18

-3.22

-2.73

PNGRTLPPVP

14.60

0.91

1.40
Q06409

FPTVPVVESD

7.26

-5.38

-4.89

KTPRPPFPFF

7.45

-4.56

-4.07

KPRKTPRPPF

7.47

-5.97

-5.48
P32634

LPPVPKAPSR

5.75

-7.19

-6.70

VPTEPTRYNY

6.29

-5.20

-4.71

LPNSPILPVL

7.22

-4.91

-4.42
Q06833

RRPVPRRPSQ

3.19

-6.80

-6.31

VPRRPSQPLN

6.45

-5.39

-4.90

FPVPPSASNM

7.16

-5.91

-5.42
P53118

PHDLPSHLGS

11.75

-1.54

-1.05

ESVENPHDLP

12.57

3.89

4.38

SVENPHDLPS

13.74

-2.98

-2.49
Q12199

APATPPRHIC

6.36

-6.49

-6.00

PATPPRHICN

8.85

-5.02

-4.53

GITTPSVQPT

10.30

-5.86

-5.37
P19158

DPSLPDTPTM

10.09

-2.99

-2.50

GEYDPSLPDT

10.10

-3.90

-3.41

PSSPPSSSSS

10.21

-3.25

-2.76
P38870

TPTTPERPKR

4.89

-6.82

-6.33

TPKPPPNDKD

8.01

-4.98

-4.49

TSSTPTTPER

9.77

-3.26

-2.77
P43638

RPIPPHPDAP

6.95

-5.54

-5.05

HPDAPKLPSA

7.38

-5.57

-5.08

AKGRPIPPHP

8.83

-4.47

-3.98
P53933

RPPPPPIPST

4.54

-6.58

-6.09

RVAPPPLPNR

5.42

-5.99

-5.50

RRRPPPPPIP

5.82

-6.42

-5.93
P50101

FPGSPIDKSI

9.72

-3.91

-3.42

GTVFPGSPID

11.04

-2.54

-2.05

VFPGSPIDKS

12.96

-2.22

-1.73
P40020

FDRPPPLTPE

5.26

-6.68

-6.19

PLPFPLYDEK

6.92

-4.47

-3.98

EPTSPTRQVN

7.13

-4.79

-4.30
P38238

PVQSPTNPPY

11.22

-2.87

-2.38

DPVQSPTNPP

11.78

-1.35

-0.86

SSLDPVQSPT

11.93

-2.11

-1.62
P00175

ELVCPPYAPG

7.61

-4.40

-3.91

LPNHPGGQDV

8.96

-6.25

-5.76

LVCPPYAPGE

9.46

-4.59

-4.10
Q08229

NPTIPPRSKD

5.77

-6.61

-6.12

NDYNPTIPPR

7.26

-4.85

-4.36

YLTRPLPSTP

7.71

-4.79

-4.30
P38930

FPDMVPKHPT

11.69

-2.35

-1.86

QAFPDMVPKH

12.99

-2.43

-1.94
Q12446

APPPPPRASR

4.08

-8.26

-7.77

RPVPPPPPMR

4.32

-7.55

-7.06

APPPPPRRGP

4.87

-6.99

-6.50
P32855

TNNAPTLPKR

7.50

-4.11

-3.62

NYSNPSSSPN

10.00

-3.82

-3.33

PSSSPNSLGN

12.62

-1.23

-0.74
Q12211

IDKRPKSGPR

6.46

-4.78

-4.29

RPKSGPRLDE

9.17

-4.11

-3.62

PKSGPRLDEN

9.38

-4.07

-3.58
Q06116

EPNSPELVPR

7.07

-4.51

-4.02

KPFYPVTSEF

7.52

-3.97

-3.48

NGVKPFYPVT

8.02

-3.37

-2.88
P33336

LPSHPSSNNM

8.37

-6.24

-5.75

DRNLPSHPSS

9.11

-3.54

-3.05

PPDRNLPSHP

11.65

-0.26

0.23
P32793

GPTHPSNMSN

8.65

-4.92

-4.43

LGHGPTHPSN

10.42

-2.76

-2.27

SLGHGPTHPS

12.99

-2.54

-2.05
P38090

SPNDPDLTAA

9.91

-4.28

-3.79

IVCSPNDPDL

12.87

-2.66

-2.17

PNDPDLTAAI

14.06

-1.62

-1.13
Q06266

FPSSPYRTVD

6.49

-5.63

-5.14

IPSSPAFPGQ

8.26

-4.21

-3.72

PYSPPNYKQQ

8.72

-4.75

-4.26
Q00916

FKPRPPLSYK

5.28

-6.43

-5.94

KPRPPLSYKR

5.52

-6.16

-5.67

RLFKPRPPLS

5.81

-5.46

-4.97
P07269

LPNTPDFLKN

7.03

-5.77

-5.28

SDSGPQRPKR

7.77

-5.72

-5.23

PDEDPNLNNQ

10.54

-3.56

-3.07
P40563

RRAPPPVPKK

5.27

-6.09

-5.60

PSERPKRRAP

5.88

-5.41

-4.92

KRRAPPPVPK

7.34

-5.31

-4.82
P10566

TRPIPAIPMD

9.26

-3.77

-3.28

NSTRPIPAIP

9.39

-3.23

-2.74

RPIPAIPMDL

9.83

-4.09

-3.60
P38289

MYDVPTNDPS

7.32

-4.58

-4.09

DPENPSFINY

8.63

-4.63

-4.14

PENPSFINYR

11.24

-6.09

-5.60
P47030

DEAFPPEPSM

9.11

-4.92

-4.43

EAFPPEPSMS

10.29

-3.39

-2.90

HNANNPLDKP

13.11

3.75

4.24
P32790

PPIKPPRPTS

4.05

-7.41

-6.92

PPAMPARPTA

5.37

-5.08

-4.59

KPPRPTSTTS

7.67

-5.29

-4.80
P32863

LPDRPPNGIG

6.77

-5.88

-5.39

PDRPPNGIGA

10.03

-5.00

-4.51
P32862

VPSTPSRSNS

6.57

-5.57

-5.08

FNYRPPNPPA

6.60

-4.73

-4.24

SNTVPSTPSR

8.01

-4.45

-3.96
P39743

AYSNPLTSPV

10.19

-3.76

-3.27

PAYSNPLTSP

13.82

3.97

4.46
P31374

RKTKPPPPLD

6.43

-5.10

-4.61

TPVFPNLDPT

6.54

-5.30

-4.81

NNISPERPSF

6.83

-3.95

-3.46
P53169

VPIMPTLPPR

4.38

-4.28

-3.79

ANSVPIMPTL

7.42

-5.92

-5.43

SPAQPSASLT

10.31

-4.51

-4.02
P53955

RNPIPYPIDA

9.54

-2.83

-2.34

LAQRNPIPYP

10.36

1.62

2.11

AQRNPIPYPI

10.59

-2.89

-2.40

 


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