ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1SSH-25.PDB
Scoring matrix: LSB3_1SSH-25_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.35
Foldx random average score for Saccharomyces cerevisiae: 16.994

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1820896
Proteins after disorder filtering: 4659
 Total fragments: 126412
Proteins after pattern filtering: 2312
 Total fragments: 21195
Proteins after MINT filtering: 75
 Total fragments: 1203


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.35

-3.39

0.00
Best peptides

EFPYMPRRR

0.00

-17.64

-14.25
         
Interactors      
P38140

IQPDLPPRK

5.74

-17.10

-13.71

PMNIQPDLP

10.61

-9.19

-5.80

QPDLPPRKI

10.73

-9.07

-5.68
Q06604

SPPPLPTRR

3.21

-17.36

-13.97

EKPLLPTRP

4.14

-16.62

-13.23

PRMPSRGRP

6.30

-11.81

-8.42
P09119

AQVPLTPTT

11.99

-6.55

-3.16

TPTTSPVKK

12.07

-7.33

-3.94

QVPLTPTTS

12.83

-7.60

-4.21
P24814

NNSTRPQMP

12.22

-8.53

-5.14

PPDIHPNLG

13.06

-6.77

-3.38

PNLGPQLWL

13.49

-6.46

-3.07
P25604

NTPPLPPKP

6.56

-12.13

-8.74

LKPPLPPPP

7.64

-12.12

-8.73

QAPSLPPKP

7.74

-11.66

-8.27
P40956

STPPLPRRR

2.97

-18.44

-15.05

TPPLPRRRA

9.60

-9.83

-6.44

ATTSTPPLP

11.41

-8.73

-5.34
P25623

DTPPLPPHA

9.44

-10.66

-7.27

SQPPLQPQS

9.95

-5.39

-2.00

KTKPLPVEP

10.57

-9.24

-5.85
Q12532

PFKPYINGG

16.39

-3.57

-0.18
P50942

PRPCPPIRR

4.96

-15.45

-12.06

PPPPPTSRH

8.49

-12.94

-9.55

PLPPVPALS

9.34

-10.85

-7.46
Q04322

TPPTLPPRR

3.85

-16.90

-13.51

TSPPLPPRA

6.03

-15.44

-12.05

PPTLPPRRI

9.10

-13.61

-10.22
P38266

QPPPKPFRR

3.66

-17.12

-13.73

AVPILPPRN

4.55

-16.30

-12.91

MPPPKPFRH

5.08

-16.48

-13.09
P47043

KPPQLPPKC

7.74

-10.75

-7.36

SKKNKPNPP

10.66

-9.33

-5.94

SDPTSPQQN

11.63

-8.06

-4.67
P15891

AQPPLPSRN

3.27

-17.16

-13.77

AAPPPPPRR

5.25

-16.06

-12.67

APPPPPRRA

7.41

-15.07

-11.68
P40341

PPPPKPPLN

7.60

-11.62

-8.23

PPPPPPPKP

8.26

-11.37

-7.98

NIPPPPPPP

10.32

-10.83

-7.44
Q12134

HQPVPSPMN

10.70

-6.85

-3.46

QPVPSPMNS

12.60

-6.91

-3.52

THQPVPSPM

14.58

-8.31

-4.92
P40494

KDKSRPPRP

6.29

-14.03

-10.64

RPPRPPPKP

8.12

-10.97

-7.58

SRPPRPPPK

8.69

-11.39

-8.00
Q12200

CPPSFPSRR

6.32

-15.07

-11.68

ELPCPVPRS

10.24

-12.86

-9.47

DEVCPPSFP

10.35

-8.42

-5.03
Q12344

SSPPLPPRQ

5.31

-15.99

-12.60

TSPKLPPRG

7.08

-15.38

-11.99

PLPPRQNVA

10.89

-6.00

-2.61
P53189

TLQPSTIPQ

14.17

-5.37

-1.98

STLQPSTIP

15.17

-5.09

-1.70
P53238

GRPIPPAPT

11.12

-8.45

-5.06

AGRPIPPAP

12.15

-8.44

-5.05

KPAGRPIPP

12.17

-8.23

-4.84
P32660

YDPTDPNRP

8.15

-14.03

-10.64

GYDPTDPNR

11.03

-6.75

-3.36

TDPNRPKVT

11.26

-8.87

-5.48
P33400

ILPPLPVGI

9.27

-11.09

-7.70

SPQILPPLP

11.20

-9.86

-6.47

SYVQPPNAP

12.55

-8.05

-4.66
P53901

PLPPIPTRD

5.88

-16.02

-12.63

NQPPLPPIP

7.10

-11.50

-8.11

AMRPIPPLP

8.25

-11.51

-8.12
P38739

SPFHDPILP

13.71

-7.16

-3.77

SPPNDPSTL

13.84

-7.87

-4.48

ASPFHDPIL

14.52

-4.73

-1.34
Q04749

PLPVLPRRI

4.38

-17.02

-13.63

FNPRKPTLS

9.64

-9.39

-6.00

NPVFNPRKP

9.76

-9.32

-5.93
P04051

QDRSLPHFP

9.48

-10.09

-6.70

SLPHFPKNS

11.54

-7.95

-4.56

PHFPKNSKT

12.60

-6.24

-2.85
P43603

TAPTSPSTS

13.19

-6.62

-3.23

RFTAPTSPS

13.70

-5.62

-2.23

GRFTAPTSP

14.36

-7.15

-3.76
P40325

SQPPRPPRP

3.03

-17.41

-14.02

SQPRPPPRP

5.09

-16.03

-12.64

PRPPRPAAN

8.05

-10.74

-7.35
P47129

GPPLLPPRN

4.96

-16.10

-12.71

KPNPPPNRS

9.11

-12.87

-9.48

NRKPNPPPN

9.63

-7.90

-4.51
P40453

KPPDLPIRL

6.16

-16.68

-13.29

IPPPLPPKI

7.01

-11.89

-8.50

RLRKRPPPP

8.67

-10.66

-7.27
P40095

PPPRSPNRP

5.89

-14.53

-11.14

RIPVLPPPR

7.83

-11.30

-7.91

IPVLPPPRS

8.85

-12.84

-9.45
Q12168

GPPPLPPRA

5.59

-16.47

-13.08

IPPPVPNRP

6.12

-16.05

-12.66

DDPYFPQFR

8.20

-8.92

-5.53
P36125

PAGPQGQRR

11.72

-11.54

-8.15

DLPAGPQGQ

12.79

-7.68

-4.29

YSNDLPAGP

13.17

-7.40

-4.01
P53142

PLIEPTTTN

13.87

-5.18

-1.79
P40528

DIPITPSHD

11.68

-8.48

-5.09

SLNDIPITP

12.34

-8.23

-4.84

NDIPITPSH

13.71

-6.56

-3.17
P36123

TTPKTPPRP

6.01

-15.55

-12.16

PPDHFPSRS

8.86

-12.12

-8.73

KTPPRPKTI

10.21

-10.73

-7.34
Q08412

VPPQLPTRT

6.43

-15.61

-12.22

ELPTQPVRK

6.84

-16.03

-12.64

KWQPLPPEP

10.35

-9.83

-6.44
P32793

HGPTHPSNM

14.46

-7.04

-3.65

SLGHGPTHP

14.58

-7.61

-4.22

GPTHPSNMS

15.47

-4.83

-1.44
Q06409

GKPRKTPRP

5.45

-14.04

-10.65

RKTPRPPFP

7.37

-9.57

-6.18

KPRKTPRPP

10.80

-8.81

-5.42
P32634

TVPTEPTRY

8.93

-14.78

-11.39

EKIPLEPLP

9.00

-9.72

-6.33

SLPNSPILP

9.05

-9.91

-6.52
Q06833

NRRPVPRRP

4.74

-15.49

-12.10

PRRPSQPLN

9.06

-3.99

-0.60

PVPRRPSQP

9.27

-10.36

-6.97
P50101

VFPGSPIDK

12.62

-8.10

-4.71

IGTVFPGSP

15.26

-6.22

-2.83

GTVFPGSPI

16.76

-5.50

-2.11
P53118

NPHDLPSHL

13.80

-8.87

-5.48

PHDLPSHLG

14.87

-4.87

-1.48

VENPHDLPS

15.30

-2.32

1.07
Q12199

AAPATPPRH

6.86

-14.77

-11.38

HICNNPNNP

13.36

-7.19

-3.80

NNPNNPQCL

13.56

-7.24

-3.85
P19158

SLPDTPTMS

9.40

-9.61

-6.22

YDPSLPDTP

11.05

-9.53

-6.14

PGEYDPSLP

12.71

-7.04

-3.65
P38870

STPTTPERP

6.62

-14.08

-10.69

TTPERPKRK

7.16

-16.38

-12.99

PTTPERPKR

9.99

-5.99

-2.60
P43638

PKLPSAFRK

10.22

-12.66

-9.27

PTNIPPPRG

10.59

-12.25

-8.86

KGRPIPPHP

10.66

-9.07

-5.68
P53933

APPPLPNRQ

5.48

-16.55

-13.16

RRPPPPPIP

8.12

-10.48

-7.09

KRVAPPPLP

9.46

-9.67

-6.28
P32790

LPPIKPPRP

4.95

-17.02

-13.63

PPPAMPARP

5.15

-17.23

-13.84

IKPPRPTST

10.04

-9.85

-6.46
P40020

EEPTSPTRQ

6.25

-14.16

-10.77

PPPLTPEKN

8.47

-10.13

-6.74

VLPPLPFPL

8.79

-11.42

-8.03
P38238

SLDPVQSPT

11.90

-4.99

-1.60

DPVQSPTNP

11.96

-7.01

-3.62

QSPTNPPYK

13.52

-8.51

-5.12
P00175

FLPNHPGGQ

11.88

-8.14

-4.75

ELVCPPYAP

12.15

-7.91

-4.52

VCPPYAPGE

15.44

-6.85

-3.46
Q08229

YNPTIPPRS

7.15

-14.53

-11.14

LTRPLPSTP

10.95

-9.61

-6.22

TNDYNPTIP

11.34

-7.23

-3.84
P38930

AFPDMVPKH

9.23

-10.97

-7.58

FPDMVPKHP

11.53

-8.96

-5.57
Q12446

PLPQLPNRN

4.24

-16.96

-13.57

PAPPPPPRR

5.18

-16.26

-12.87

APPPPPHRH

6.54

-16.14

-12.75
P32855

NAPTLPKRK

7.30

-16.46

-13.07

ATNNAPTLP

13.66

-7.67

-4.28

YSNPSSSPN

14.11

-3.36

0.03
Q12211

KRPKSGPRL

7.85

-12.85

-9.46

DKRPKSGPR

9.64

-7.75

-4.36

NGNPLPKEP

12.00

-7.72

-4.33
Q06116

NSPELVPRS

10.43

-12.91

-9.52

VKPFYPVTS

12.98

-7.36

-3.97

HSEPVEPFS

13.23

-3.99

-0.60
P33336

NLPSHPSSN

10.89

-7.89

-4.50

PDRNLPSHP

11.09

-9.43

-6.04

DRNLPSHPS

14.36

-4.41

-1.02
P40041

NGRTLPPVP

11.71

-8.79

-5.40

KIPLSPPSS

12.06

-7.60

-4.21

IPLSPPSSS

15.17

-5.60

-2.21
P38090

CSPNDPDLT

13.04

-7.33

-3.94

GIVCSPNDP

13.70

-6.52

-3.13
Q06266

QFPSSPYRT

5.54

-13.97

-10.58

AIPSSPAFP

9.36

-9.22

-5.83

SQFPSSPYR

11.50

-5.75

-2.36
Q00916

PRPPLSYKR

6.15

-10.98

-7.59

LFKPRPPLS

7.85

-10.22

-6.83

SRLFKPRPP

9.18

-11.14

-7.75
P07269

ELPNTPDFL

8.66

-9.63

-6.24

ASDSGPQRP

9.85

-12.51

-9.12

DSGPQRPKR

11.39

-5.36

-1.97
P40563

VTPKVPERP

6.92

-15.83

-12.44

APPPVPKKP

7.94

-11.38

-7.99

KRRAPPPVP

10.57

-8.69

-5.30
P10566

STRPIPAIP

10.57

-9.49

-6.10

PIPAIPMDL

13.06

-8.95

-5.56

PAIPMDLPD

14.05

-5.76

-2.37
P38289

EDPENPSFI

10.82

-8.07

-4.68

DPENPSFIN

14.73

-4.73

-1.34

YDVPTNDPS

14.77

-5.26

-1.87
P47030

AFPPEPSMS

8.52

-10.52

-7.13

TETKPPRAP

12.78

-8.29

-4.90

TDEAFPPEP

13.78

-6.56

-3.17
P32863

LPDRPPNGI

13.54

-7.09

-3.70

PDRPPNGIG

16.30

-5.38

-1.99
P32862

TVPSTPSRS

7.16

-13.99

-10.60

DFNYRPPNP

8.54

-8.57

-5.18

YRPPNPPAN

9.17

-9.75

-6.36
P39743

YSNPLTSPV

14.05

-4.84

-1.45

SNPLTSPVA

14.43

-5.40

-2.01

NATIPEDNP

15.87

-2.39

1.00
P31374

ISPERPSFR

7.84

-9.98

-6.59

KKPGTPVFP

8.44

-9.54

-6.15

GNNISPERP

8.46

-12.59

-9.20
P53169

IMPTLPPRP

3.85

-17.44

-14.05

SVPIMPTLP

8.29

-11.63

-8.24

TANSVPIMP

12.46

-8.96

-5.57
Q07660

PSAFKPIGP

13.73

-7.27

-3.88
P53955

QRNPIPYPI

10.98

-8.02

-4.63

NPIPYPIDA

14.76

-6.86

-3.47

AQRNPIPYP

14.79

-5.53

-2.14

 


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