ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1SSH-20.PDB
Scoring matrix: LSB3_1SSH-20_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.92
Foldx random average score for Saccharomyces cerevisiae: 14.527

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1490279
Proteins after disorder filtering: 4555
 Total fragments: 79810
Proteins after pattern filtering: 2064
 Total fragments: 8142
Proteins after MINT filtering: 68
 Total fragments: 459


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.92

-0.65

0.00
Best peptides

FKFMRGWSR

0.00

-5.54

-4.89
         
Interactors      
P38140

NIQPDLPPR

11.68

-4.79

-4.14

IPPHPYPSS

12.05

-5.74

-5.09

PDLPPRKIM

12.05

-6.71

-6.06
Q06604

EKGPRMPSR

6.11

-5.63

-4.98

GPRMPSRGR

7.42

-8.82

-8.17

NKPKPTPPS

10.86

-4.62

-3.97
P24814

HPPDIHPNL

10.55

-5.85

-5.20

IHPNLGPQL

11.68

-3.58

-2.93

NSTRPQMPS

13.62

-3.78

-3.13
P25604

LPPKPKSPH

8.78

-7.89

-7.24

LPPKPNTQL

9.43

-8.40

-7.75

PPKPKSPHL

10.42

-7.48

-6.83
P40956

TSTPPLPRR

9.86

-5.85

-5.20

TPPLPRRRA

11.12

-9.40

-8.75

PPLPRRRAT

11.61

-5.90

-5.25
P25623

EPASPSISL

10.03

-5.29

-4.64

SDTPPLPPH

11.97

-4.55

-3.90

KPLPVEPAS

12.56

-4.29

-3.64
Q04322

DQAPLDRPQ

12.29

-4.78

-4.13

TPPTLPPRR

13.84

-7.07

-6.42

STPPTLPPR

14.18

-3.88

-3.23
P38266

FLPPPKPFR

7.24

-8.24

-7.59

FQPPPKPFR

7.46

-9.77

-9.12

APTPPAPSR

7.83

-7.23

-6.58
P47043

PQLPPKCSS

11.80

-4.78

-4.13

ASDPTSPQQ

13.00

-3.20

-2.55

SKPPQLPPK

14.10

-4.99

-4.34
P15891

AAQPPLPSR

9.37

-5.96

-5.31

QPPLPSRNV

10.40

-9.48

-8.83

PPPPPRRAT

12.05

-7.34

-6.69
P40341

KPPLNDPSN

11.84

-6.33

-5.68

PPPPPKPPL

12.14

-8.66

-8.01
Q12134

HQPVPSPMN

12.13

-6.16

-5.51

PVPSPMNSQ

13.01

-4.57

-3.92
P40494

PRPPPKPLH

9.41

-6.91

-6.26

NQPPNMMPV

12.36

-4.19

-3.54

QPPNMMPVT

13.96

-4.31

-3.66
Q12200

VCPPSFPSR

10.35

-4.13

-3.48

PPSFPSRRC

11.63

-7.43

-6.78

LPCPVPRSF

11.84

-6.99

-6.34
Q12344

PKLPPRGKQ

10.65

-7.14

-6.49

PPLPPRQNV

11.30

-8.51

-7.86

TSSPPLPPR

12.37

-6.92

-6.27
P53189

TLQPSTIPQ

14.24

-2.52

-1.87
P53238

PPAPTHYNN

10.45

-5.80

-5.15

RPIPPAPTH

10.64

-5.92

-5.27

IPPAPTHYN

12.62

-5.18

-4.53
P32660

GYDPTDPNR

11.16

-5.51

-4.86

DPNRPKVTK

13.31

-6.78

-6.13

PMSPFEDTF

14.32

-4.80

-4.15
P33400

VQPPNAPSY

11.53

-3.92

-3.27

PPNAPSYQS

12.48

-4.58

-3.93

QILPPLPVG

12.82

-5.44

-4.79
P53901

LPPLPTTSN

11.03

-7.14

-6.49

IPPLPTESE

12.40

-6.07

-5.42

PPLPPIPTR

12.44

-8.54

-7.89
P38739

GSPPNDPST

13.60

-2.24

-1.59

TSPSTAPSS

14.30

-0.39

0.26
Q04749

NPRKPTLST

8.57

-6.18

-5.53

SPLPVLPRR

8.78

-6.89

-6.24

PVLPRRIST

12.29

-3.89

-3.24
P04051

RSLPHFPKN

11.92

-3.26

-2.61

LPHFPKNSK

11.94

-7.14

-6.49

PAMLPGSSN

12.42

-5.58

-4.93
P43603

APTSPSTSS

12.40

-3.53

-2.88

FTAPTSPST

12.43

-1.29

-0.64
P40325

RPPRPAANL

8.21

-7.68

-7.03

LYVQPGDPR

10.38

-4.76

-4.11

PRPPPRPQQ

10.64

-6.84

-6.19
P47129

PNPPPNRSQ

10.80

-7.43

-6.78

RKPNPPPNR

12.29

-8.40

-7.75

PLLPPRNTM

13.47

-7.86

-7.21
P40453

WKPPDLPIR

10.04

-5.90

-5.25

PDLPIRLRK

10.68

-6.38

-5.73

PPDLPIRLR

11.41

-10.50

-9.85
P40095

LPPPRSPNR

5.26

-8.89

-8.24

FPDSPSSSS

10.76

-4.49

-3.84

PDSPSSSSL

10.86

-4.35

-3.70
Q12168

NDDPYFPQF

10.24

-4.31

-3.66

PLPPRANVQ

11.26

-5.44

-4.79

PPLPPRANV

11.45

-6.96

-6.31
P36125

NDLPAGPQG

9.33

-3.88

-3.23

PAGPQGQRR

9.40

-5.21

-4.56

LPAGPQGQR

10.93

-6.43

-5.78
P32793

GHGPTHPSN

13.19

-2.15

-1.50

GPTHPSNMS

13.97

-5.16

-4.51
P40528

NDIPITPSH

6.82

-4.77

-4.12

IPITPSHDN

13.90

-4.44

-3.79

PITPSHDNN

13.97

-4.50

-3.85
P36123

FPPDHFPSR

7.85

-5.21

-4.56

PDHFPSRSQ

11.05

-6.77

-6.12

PKTPPRPKT

11.84

-5.28

-4.63
Q08412

LPTQPVRKN

11.34

-7.36

-6.71

IELPTQPVR

11.82

-4.49

-3.84

KKWQPLPPE

13.11

-4.36

-3.71
P32855

NNAPTLPKR

9.89

-5.05

-4.40
Q06409

TPRPPFPFF

10.61

-7.84

-7.19

TPRNPDPYG

12.62

-4.02

-3.37

TGKPRKTPR

12.63

-5.52

-4.87
P32634

PPVPKAPSR

7.40

-6.68

-6.03

LPIVPNPNL

10.45

-6.68

-6.03

VPTEPTRYN

12.23

-4.63

-3.98
Q06833

RPVPRRPSQ

7.51

-6.44

-5.79

FPVPPSASN

8.81

-6.89

-6.24

VPRRPSQPL

11.48

-6.14

-5.49
P50101

PGSPIDKSI

13.54

-5.72

-5.07

FPGSPIDKS

14.00

-4.53

-3.88
P53118

ENPHDLPSH

12.24

-3.88

-3.23

PHDLPSHLG

14.22

-6.52

-5.87
Q12199

NPNNPQCLH

11.60

-3.77

-3.12

TAAPATPPR

13.50

-4.38

-3.73
P19158

SMTPVSPLG

11.63

-4.37

-3.72

PSSPPSSSS

12.50

-2.94

-2.29
P38870

TPERPKRKS

9.27

-7.29

-6.64

PTTPERPKR

12.22

-5.04

-4.39

PKPPPNDKD

13.39

-4.96

-4.31
P43638

PDAPKLPSA

10.47

-4.07

-3.42

APKLPSAFR

10.58

-7.18

-6.53

PKLPSAFRK

10.74

-7.19

-6.54
P53933

VAPPPLPNR

9.45

-6.85

-6.20

NDLPMELPH

10.22

-4.80

-4.15

PPPLPNRQL

12.02

-9.99

-9.34
P32790

GPPPAMPAR

11.18

-6.30

-5.65

APAPLDPFK

12.10

-5.39

-4.74

PPAMPARPT

12.12

-6.94

-6.29
P40020

PPLTPEKNL

10.77

-7.60

-6.95

SEEPTSPTR

11.97

-4.56

-3.91

EPTSPTRQV

12.10

-5.93

-5.28
P38238

LDPVQSPTN

14.00

-4.86

-4.21
P00175

RFLPNHPGG

11.88

-3.85

-3.20

LPNHPGGQD

12.28

-4.71

-4.06

TRFLPNHPG

13.66

-4.84

-4.19
Q08229

TPVQPGGHY

11.01

-5.85

-5.20

PSTPNEDSR

11.07

-3.43

-2.78

LPTPVQPGG

11.75

-5.81

-5.16
P38930

AFPDMVPKH

14.45

-3.38

-2.73
Q12446

PPPPPRASR

7.76

-9.36

-8.71

RPLPQLPNR

8.21

-6.93

-6.28

PPPPPHRHV

9.95

-9.61

-8.96
Q12211

KRPKSGPRL

6.92

-6.57

-5.92

DKRPKSGPR

9.91

-5.34

-4.69

GNPLPKEPR

14.17

-6.27

-5.62
Q06116

NGVKPFYPV

12.93

-3.38

-2.73

NSPELVPRS

13.49

-3.05

-2.40

HSEPVEPFS

13.58

-2.40

-1.75
P33336

LPSHPSSNN

11.48

-6.89

-6.24

RNLPSHPSS

12.04

-2.67

-2.02

PSHPSSNNM

13.13

-5.16

-4.51
P40041

PLSPPSSSN

11.18

-5.18

-4.53
P50942

LPPVPALSL

8.89

-7.50

-6.85

PPPPPTSRH

9.29

-8.27

-7.62

RPCPPIRRK

10.05

-8.94

-8.29
Q06266

SQFPSSPYR

10.58

-4.31

-3.66

QPNCPSSNY

11.95

-6.25

-5.60

PYSPPNYKQ

11.97

-4.42

-3.77
Q00916

PRPPLSYKR

6.54

-7.80

-7.15

RLFKPRPPL

10.29

-8.60

-7.95

YKRPTDYPY

11.82

-4.15

-3.50
P07269

LPNTPDFLK

11.09

-6.96

-6.31

DSGPQRPKR

11.39

-4.67

-4.02

NAPDEDPNL

12.87

-3.77

-3.12
P40563

PSERPKRRA

10.13

-7.83

-7.18

NSQPQGPSD

10.94

-1.79

-1.14

NSEPPTPAG

11.66

-4.28

-3.63
P10566

RPIPAIPMD

13.78

-4.76

-4.11

AIPMDLPDY

14.48

-3.81

-3.16

TRPIPAIPM

14.52

-4.88

-4.23
P38289

DVPTNDPSG

13.24

-2.71

-2.06

DPENPSFIN

13.31

-5.52

-4.87

PENPSFINY

13.43

-5.13

-4.48
P47030

FPPEPSMSS

8.29

-5.41

-4.76

EAFPPEPSM

9.94

-6.44

-5.79
P32863

PDRPPNGIG

14.08

-6.40

-5.75
P32862

NTVPSTPSR

10.22

-3.43

-2.78

VPSTPSRSN

10.25

-5.06

-4.41

SSPGSTPQR

13.45

-3.00

-2.35
P31374

SPERPSFRQ

7.55

-10.37

-9.72

NISPERPSF

9.39

-4.31

-3.66

FEQPRLPST

9.79

-4.28

-3.63
P53169

SPAQPSASL

9.90

-4.73

-4.08

NSVPIMPTL

12.63

-4.89

-4.24

PIMPTLPPR

12.82

-5.26

-4.61

 


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