ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1SSH-14.PDB
Scoring matrix: LSB3_1SSH-14_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.57
Foldx random average score for Saccharomyces cerevisiae: 16.304

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1387819
Proteins after disorder filtering: 4172
 Total fragments: 41792
Proteins after pattern filtering: 1780
 Total fragments: 5985
Proteins after MINT filtering: 64
 Total fragments: 398


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.57

-1.38

0.00
Best peptides

KWPIIRKMR

0.00

-9.73

-8.35
         
Interactors      
P38140

PDLPPRKIM

8.23

-9.72

-8.34

QPDLPPRKI

13.56

-8.42

-7.04

NIQPDLPPR

13.96

-8.41

-7.03
Q06604

PLLPTRPNK

9.82

-8.04

-6.66

TPPSPPAKR

11.82

-8.05

-6.67

EEKPLLPTR

11.89

-4.57

-3.19
P09119

TPTTSPVKK

13.15

-7.43

-6.05

LTPTTSPVK

14.51

-3.55

-2.17
P24814

HPPDIHPNL

12.71

-6.17

-4.79

PPDIHPNLG

13.97

-7.54

-6.16

HPNLGPQLW

16.11

-6.52

-5.14
P25604

LPPKPKSPH

12.74

-7.67

-6.29

PKPKSPHLK

12.82

-9.95

-8.57

KSPHLKPPL

13.75

-4.27

-2.89
P40956

TPPLPRRRA

10.09

-10.18

-8.80

PPLPRRRAT

12.00

-10.60

-9.22

TSTPPLPRR

13.70

-4.75

-3.37
P25623

PPHATPKNV

13.97

-6.44

-5.06

LPKTVPISI

14.39

-6.53

-5.15

PHATPKNVD

14.70

-3.58

-2.20
Q04322

TPPTLPPRR

11.14

-9.85

-8.47

QAPLDRPQL

12.54

-8.83

-7.45

PPTLPPRRI

13.76

-8.67

-7.29
P38266

PPPPTHRDR

9.61

-9.59

-8.21

KPPVVPKKK

9.65

-9.78

-8.40

PPPPSRGNF

10.76

-9.51

-8.13
P47043

KPPQLPPKC

13.14

-6.42

-5.04
P15891

PPLPSRNVA

10.43

-9.07

-7.69

PPPPPRRAT

12.19

-12.11

-10.73

TPSKSPAPV

13.79

-6.65

-5.27
P40341

PPPPPKPPL

14.07

-8.23

-6.85

PPPKPPLND

14.40

-7.06

-5.68

PPPPPPPPK

15.14

-10.11

-8.73
P40494

QPPNMMPVT

14.03

-7.02

-5.64

PNMMPVTHV

14.67

-6.69

-5.31

KPTLIPDNG

15.50

-6.07

-4.69
Q12200

PCPVPRSFE

11.26

-8.58

-7.20

CPPSFPSRR

11.59

-8.13

-6.75

SCPHLKPLK

13.02

-5.22

-3.84
Q12344

PPLPPRQNV

10.56

-9.88

-8.50

PKLPPRGKQ

12.49

-9.52

-8.14

TSSPPLPPR

14.53

-4.79

-3.41
P53238

PPAPTHYNN

15.23

-7.87

-6.49
P32660

DPNRPKVTK

11.20

-6.70

-5.32

PTDPNRPKV

11.22

-8.67

-7.29

TDPNRPKVT

15.94

-3.30

-1.92
P33400

TSPQILPPL

15.01

-3.94

-2.56

ILPPLPVGI

15.54

-4.54

-3.16

QPPNAPSYQ

16.07

-6.28

-4.90
P53901

PPIPTRDDM

9.63

-6.14

-4.76

NDPIILPPT

12.98

-7.12

-5.74

DPIILPPTF

13.35

-7.93

-6.55
P38739

PFHDPILPR

14.24

-6.39

-5.01

LASPFHDPI

15.18

-5.87

-4.49

ASPFHDPIL

15.92

-2.05

-0.67
Q04749

LPVLPRRIS

10.94

-10.49

-9.11

SPLPVLPRR

11.50

-6.56

-5.18

PLPVLPRRI

12.26

-7.66

-6.28
P04051

LPHFPKNSK

10.93

-6.63

-5.25

DRSLPHFPK

13.55

-8.81

-7.43
P40325

SLPWTYPPR

10.91

-7.77

-6.39

QSQPPRPPR

11.04

-10.43

-9.05

PPRPPRPAA

11.98

-10.40

-9.02
P47129

PLLPPRNTM

10.56

-6.57

-5.19

RKPNPPPNR

13.06

-8.34

-6.96

SGPPLLPPR

14.96

-5.19

-3.81
P40453

PDLPIRLRK

8.53

-8.12

-6.74

PPDLPIRLR

11.97

-9.04

-7.66

WKPPDLPIR

12.03

-6.28

-4.90
P40095

RIPVLPPPR

10.94

-9.53

-8.15

LPPPRSPNR

12.89

-9.05

-7.67

PRSPNRPTL

13.27

-8.01

-6.63
Q12168

PPLPPRANV

10.06

-10.52

-9.14

DDPYFPQFR

12.10

-7.08

-5.70

QHPVPKPNI

12.12

-6.36

-4.98
P36125

LPAGPQGQR

15.72

-6.61

-5.23

PAGPQGQRR

16.26

-7.60

-6.22
P32793

HGPTHPSNM

15.69

-3.12

-1.74
P40528

DIPITPSHD

14.68

-6.09

-4.71

PLPYPIAQV

15.75

-5.62

-4.24
P36123

FPPDHFPSR

12.52

-8.12

-6.74

PKTPPRPKT

13.32

-10.08

-8.70

TPKTPPRPK

15.01

-8.15

-6.77
Q08412

IELPTQPVR

13.50

-3.79

-2.41

DVPPQLPTR

13.62

-5.76

-4.38

PQLPTRTKS

13.64

-6.98

-5.60
P32855

NNAPTLPKR

12.31

-5.57

-4.19

NAPTLPKRK

13.96

-9.08

-7.70
Q06409

PRKTPRPPF

12.58

-9.54

-8.16

TGKPRKTPR

14.08

-3.27

-1.89

ANSTPRNPD

14.61

-7.27

-5.89
P32634

CYPLNLPIV

12.38

-8.19

-6.81

PTEPTRYNY

12.87

-6.56

-5.18

QEKIPLEPL

13.35

-6.94

-5.56
Q06833

RPVPRRPSQ

12.17

-7.95

-6.57

RRPVPRRPS

12.69

-9.21

-7.83

RPSQPLNTL

13.55

-5.49

-4.11
P50101

VFPGSPIDK

16.07

-2.60

-1.22
P53118

NPHDLPSHL

15.64

-4.13

-2.75
Q12199

PATPPRHIC

12.76

-8.90

-7.52

APATPPRHI

14.44

-7.07

-5.69

TPSVQPTAA

15.47

-5.04

-3.66
P19158

MTPVSPLGL

15.08

-5.59

-4.21
P38870

PTTPERPKR

8.49

-9.02

-7.64

TPERPKRKS

13.30

-7.10

-5.72

TTPERPKRK

15.03

-6.00

-4.62
P43638

APKLPSAFR

12.74

-10.41

-9.03

VPTNIPPPR

13.27

-8.03

-6.65

RPIPPHPDA

14.49

-7.97

-6.59
P53933

PPPIPSTQK

12.39

-9.91

-8.53

VAPPPLPNR

14.29

-8.94

-7.56

SYPGNPTSR

15.44

-6.17

-4.79
P32790

GPPPAMPAR

12.36

-7.69

-6.31

PAMPARPTA

13.55

-7.07

-5.69

PIKPPRPTS

15.03

-9.15

-7.77
P40020

PHSIPFSVL

12.93

-7.35

-5.97

LTPESPLNR

13.16

-7.49

-6.11

PPYLSPQNK

13.21

-7.63

-6.25
P38238

QSPTNPPYK

15.05

-6.23

-4.85
P00175

RFLPNHPGG

15.68

-6.67

-5.29
Q08229

NPTIPPRSK

12.33

-10.24

-8.86

PTIPPRSKD

13.38

-7.75

-6.37

DYNPTIPPR

15.63

-5.50

-4.12
P38930

PDMVPKHPT

13.26

-7.23

-5.85

QAFPDMVPK

15.83

-4.77

-3.39
Q12446

PPPPPRASR

8.17

-15.19

-13.81

PQLPNRNNR

9.38

-9.03

-7.65

PPPPHRHVT

11.03

-10.66

-9.28
Q12211

GNPLPKEPR

12.51

-7.42

-6.04

PKSGPRLDE

14.11

-8.10

-6.72

KRPKSGPRL

15.11

-7.21

-5.83
Q06116

PELVPRSST

11.04

-11.40

-10.02

PNSPELVPR

14.18

-4.96

-3.58

NGVKPFYPV

15.35

-7.01

-5.63
P50942

PRPCPPIRR

12.24

-10.51

-9.13

VPRPCPPIR

12.56

-8.43

-7.05

PCPPIRRKS

12.99

-10.90

-9.52
Q06266

PSSPYRTVD

12.76

-6.13

-4.75

FPSSPYRTV

13.57

-7.96

-6.58

DPYSPPNYK

14.59

-8.43

-7.05
Q00916

RLFKPRPPL

9.57

-9.25

-7.87

PTDYPYAKR

10.66

-5.47

-4.09

PRPPLSYKR

13.01

-10.03

-8.65
P07269

DSGPQRPKR

9.02

-7.93

-6.55

LPNTPDFLK

15.30

-7.43

-6.05

ELPNTPDFL

15.57

-4.81

-3.43
P40563

PSERPKRRA

12.79

-6.73

-5.35

PPPVPKKPS

13.57

-8.26

-6.88

EVTPKVPER

14.77

-6.81

-5.43
P10566

AIPMDLPDY

14.00

-5.96

-4.58

TRPIPAIPM

14.42

-7.79

-6.41

PIPAIPMDL

15.78

-4.89

-3.51
P38289

EDPENPSFI

14.60

-4.33

-2.95

VPTNDPSGI

16.08

-3.83

-2.45

PENPSFINY

16.10

-4.84

-3.46
P32863

LPDRPPNGI

13.76

-7.05

-5.67
P32862

NPSNSPNSM

14.40

-6.53

-5.15

PSTPSRSNS

14.84

-5.30

-3.92

PPANNPTVQ

15.37

-5.72

-4.34
P31374

ISPERPSFR

12.52

-6.43

-5.05

NISPERPSF

12.93

-7.45

-6.07

DFEQPRLPS

13.70

-8.06

-6.68
P53169

PIMPTLPPR

12.49

-7.05

-5.67

MPTLPPRPY

16.00

-8.24

-6.86

NSVPIMPTL

16.04

-2.16

-0.78
P53955

RNPIPYPID

12.38

-6.69

-5.31

NQNDPRSPL

14.27

-6.70

-5.32

PIPYPIDAV

15.67

-5.24

-3.86

 


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