ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1SSH-13.PDB
Scoring matrix: LSB3_1SSH-13_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 18.72
Foldx random average score for Saccharomyces cerevisiae: 13.893

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1504116
Proteins after disorder filtering: 4531
 Total fragments: 70586
Proteins after pattern filtering: 2130
 Total fragments: 12097
Proteins after MINT filtering: 72
 Total fragments: 732


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

18.72

-3.16

0.00
Best peptides

RPPFRPRK

0.00

-15.93

-12.77
         
Interactors      
P38140

QPDLPPRK

6.34

-14.19

-11.03

PDLPPRKI

11.90

-7.94

-4.78

IPPHPYPS

12.43

-7.50

-4.34
Q06604

PPPLPTRR

6.16

-14.14

-10.98

GPRMPSRG

6.65

-14.42

-11.26

KPLLPTRP

6.80

-13.03

-9.87
P09119

QVPLTPTT

10.41

-6.24

-3.08

PLTPTTSP

12.97

-4.27

-1.11

LTPTTSPV

13.26

-3.36

-0.20
P24814

HPPDIHPN

11.40

-7.16

-4.00

HPNLGPQL

12.96

-7.23

-4.07

NSTRPQMP

13.34

-8.42

-5.26
P25604

TPPLPPKP

7.20

-10.75

-7.59

PLPPKPKS

8.16

-8.32

-5.16

APSLPPKP

8.41

-9.78

-6.62
P40956

TPPLPRRR

6.02

-15.84

-12.68

PPLPRRRA

7.00

-12.75

-9.59

STPPLPRR

9.74

-12.24

-9.08
P25623

QPPLQPQS

8.20

-8.57

-5.41

TPPLPPHA

9.01

-10.28

-7.12

PPHATPKN

9.51

-6.45

-3.29
P50942

PPPPTSRH

6.66

-10.53

-7.37

RPCPPIRR

7.51

-13.93

-10.77

PCPPIRRK

8.14

-11.17

-8.01
Q04322

SPPLPPRA

5.31

-13.74

-10.58

PPTLPPRR

7.01

-13.34

-10.18

APLDRPQL

10.04

-7.99

-4.83
P38266

PPPKPFRH

6.90

-14.01

-10.85

PPPKPFRR

7.10

-15.07

-11.91

VPILPPRN

7.11

-14.57

-11.41
P47043

PPQLPPKC

8.96

-10.48

-7.32

KPPQLPPK

10.39

-8.64

-5.48

SKPPQLPP

12.53

-4.85

-1.69
P15891

QPPLPSRN

6.10

-14.03

-10.87

APPPPPRR

7.85

-12.81

-9.65

TPEKKPKE

7.95

-9.52

-6.36
P40341

PPPPPPKP

9.45

-9.87

-6.71

KPPLNDPS

9.63

-8.40

-5.24

PPPKPPLN

10.29

-11.01

-7.85
Q12134

QPVPSPMN

13.79

-7.61

-4.45
P40494

RPPPKPLH

6.76

-10.18

-7.02

RPPRPPPK

8.11

-10.22

-7.06

DKSRPPRP

9.03

-11.05

-7.89
Q12200

CPHLKPLK

6.79

-10.80

-7.64

PPSFPSRR

7.15

-15.43

-12.27

LPCPVPRS

8.04

-12.53

-9.37
Q12344

SPPLPPRQ

5.27

-13.75

-10.59

SPKLPPRG

6.26

-12.09

-8.93

PLPPRQNV

10.58

-7.25

-4.09
P53189

LQPSTIPQ

12.38

-4.45

-1.29
P53238

KPAGRPIP

8.72

-9.52

-6.36

PPAPTHYN

11.09

-5.90

-2.74

IPPAPTHY

11.79

-8.52

-5.36
P32660

TDPNRPKV

7.60

-8.63

-5.47

DPTDPNRP

9.36

-11.39

-8.23

DPNRPKVT

11.56

-8.82

-5.66
P33400

LPPLPVGI

10.11

-9.72

-6.56

ILPPLPVG

11.45

-6.74

-3.58

PQILPPLP

11.66

-9.58

-6.42
P53901

LPPIPTRD

6.98

-14.01

-10.85

QPPLPPIP

7.60

-11.38

-8.22

SPKLPPLP

9.24

-10.76

-7.60
P38739

SPFHDPIL

12.67

-6.10

-2.94

PFHDPILP

13.10

-7.73

-4.57
Q04749

NPVFNPRK

4.50

-14.18

-11.02

LPVLPRRI

6.01

-15.23

-12.07

PLPVLPRR

7.63

-11.74

-8.58
P04051

LPHFPKNS

9.68

-10.05

-6.89

NPAMLPGS

10.95

-7.92

-4.76

SLPHFPKN

11.10

-7.01

-3.85
P43603

RFTAPTSP

12.78

-6.43

-3.27
P40325

QPPRPPRP

6.05

-13.77

-10.61

RPPPRPQQ

6.84

-9.62

-6.46

QPRPPPRP

7.78

-14.38

-11.22
P47129

PPLLPPRN

7.15

-13.47

-10.31

LPNRKPNP

8.27

-8.37

-5.21

GPPLLPPR

9.64

-9.86

-6.70
P40453

PPPLPPKI

7.39

-11.52

-8.36

PPDLPIRL

7.46

-13.31

-10.15

KPPDLPIR

8.78

-9.15

-5.99
P40095

LPPPRSPN

8.99

-8.56

-5.40

PPRSPNRP

9.40

-11.42

-8.26

RSPNRPTL

10.34

-6.41

-3.25
Q12168

PPPLPPRA

5.94

-14.26

-11.10

PPPVPNRP

8.35

-13.70

-10.54

PYFPQFRS

8.86

-10.64

-7.48
P32793

GPTHPSNM

12.97

-7.44

-4.28
P40528

PLPYPIAQ

11.77

-7.60

-4.44

DIPITPSH

11.77

-5.83

-2.67

NDIPITPS

12.73

-5.86

-2.70
P36123

PDHFPSRS

7.89

-13.41

-10.25

TPKTPPRP

8.68

-12.72

-9.56

KTPPRPKT

9.63

-7.98

-4.82
Q08412

LPTQPVRK

7.41

-13.68

-10.52

PPQLPTRT

7.70

-14.55

-11.39

ELPTQPVR

10.28

-7.35

-4.19
Q06697

GGPRKDPI

13.38

-4.79

-1.63
Q06409

KPRKTPRP

4.93

-12.74

-9.58

RKTPRPPF

10.35

-6.62

-3.46

GKPRKTPR

11.03

-6.97

-3.81
P32634

PLPPQEKI

9.53

-7.21

-4.05

YPLNLPIV

9.64

-9.05

-5.89

CYPLNLPI

9.86

-7.02

-3.86
Q06833

RRPVPRRP

7.18

-12.95

-9.79

RPVPRRPS

9.21

-9.28

-6.12

RRPSQPLN

10.04

-7.25

-4.09
P53118

NPHDLPSH

11.86

-6.75

-3.59

PHDLPSHL

13.27

-7.20

-4.04
Q12199

APATPPRH

8.89

-11.40

-8.24

TPSVQPTA

12.35

-5.67

-2.51

NNPNNPQC

12.37

-4.43

-1.27
P19158

SLPDTPTM

10.43

-4.68

-1.52

LPDTPTMS

11.33

-10.31

-7.15

DPSLPDTP

11.69

-8.77

-5.61
P38870

TPERPKRK

7.36

-13.19

-10.03

TPTTPERP

9.63

-12.92

-9.76

PERPKRKS

10.36

-8.28

-5.12
P43638

APKLPSAF

11.49

-8.13

-4.97

GRPIPPHP

12.05

-7.36

-4.20

VPTNIPPP

12.19

-7.86

-4.70
P53933

PPPLPNRQ

6.51

-14.13

-10.97

RPPPPPIP

7.77

-10.32

-7.16

APPPLPNR

11.04

-8.30

-5.14
P50101

VFPGSPID

13.79

-5.06

-1.90
P40020

PPPLTPEK

8.63

-7.49

-4.33

LPPLPFPL

9.16

-9.84

-6.68

LPPYLSPQ

9.33

-8.47

-5.31
P38238

SPTNPPYK

10.82

-8.11

-4.95

LDPVQSPT

11.19

-4.53

-1.37
P00175

TRFLPNHP

11.55

-7.71

-4.55

RFLPNHPG

11.97

-5.41

-2.25

CPPYAPGE

12.39

-7.21

-4.05
Q08229

NPTIPPRS

8.18

-12.98

-9.82

NDYNPTIP

10.85

-7.44

-4.28

TRPLPSTP

11.73

-8.22

-5.06
P38930

FPDMVPKH

7.25

-12.56

-9.40

AFPDMVPK

11.35

-5.66

-2.50

PDMVPKHP

13.13

-7.34

-4.18
Q12446

LPQLPNRN

6.61

-13.16

-10.00

APPPPPRR

7.85

-12.81

-9.65

APPPPPRA

8.00

-14.00

-10.84
P32855

APTLPKRK

6.70

-13.54

-10.38

NAPTLPKR

10.97

-9.16

-6.00

NNAPTLPK

13.41

-3.60

-0.44
Q12211

RPKSGPRL

9.67

-12.19

-9.03

NPLPKEPR

11.59

-6.82

-3.66

MQYNPPNP

12.01

-6.29

-3.13
Q06116

SPELVPRS

6.34

-14.38

-11.22

KPFYPVTS

11.52

-8.68

-5.52

SEPVEPFS

13.61

-6.74

-3.58
P33336

DRNLPSHP

11.84

-7.79

-4.63

LPSHPSSN

12.48

-7.81

-4.65
P40041

GRTLPPVP

11.76

-7.67

-4.51

KIPLSPPS

13.32

-6.49

-3.33
P38090

SPNDPDLT

12.65

-8.01

-4.85
Q06266

FPSSPYRT

9.27

-12.21

-9.05

SPAFPGQL

10.44

-8.97

-5.81

GDYPTPFP

10.68

-4.97

-1.81
Q00916

LFKPRPPL

10.10

-7.56

-4.40

FKPRPPLS

10.43

-10.31

-7.15

YKRPTDYP

10.59

-5.41

-2.25
P07269

SGPQRPKR

9.86

-8.65

-5.49

SDSGPQRP

10.74

-10.49

-7.33

ELPNTPDF

11.69

-4.39

-1.23
P40563

APPPVPKK

8.71

-10.35

-7.19

TPKVPERP

9.27

-12.11

-8.95

PPPVPKKP

9.73

-10.09

-6.93
P10566

TRPIPAIP

11.38

-8.13

-4.97

PIPAIPMD

11.53

-9.29

-6.13

RPIPAIPM

12.86

-6.13

-2.97
P38289

EDPENPSF

12.29

-5.12

-1.96

DPENPSFI

12.49

-7.64

-4.48

YDVPTNDP

13.16

-3.52

-0.36
P47030

FPPEPSMS

10.72

-10.38

-7.22

ANNPLDKP

12.92

-5.57

-2.41

DEAFPPEP

13.54

-8.59

-5.43
P32790

PPAMPARP

7.41

-13.95

-10.79

PPIKPPRP

7.99

-13.83

-10.67

LPPIKPPR

8.74

-9.95

-6.79
P32863

LPDRPPNG

10.51

-9.47

-6.31
P32862

VPSTPSRS

9.82

-12.13

-8.97

RPPNPPAN

10.36

-7.82

-4.66

QPQLPPPQ

11.60

-9.02

-5.86
P39743

SNPLTSPV

10.87

-5.28

-2.12
P31374

SPERPSFR

10.52

-9.06

-5.90

PDDLPPLK

10.59

-10.26

-7.10

QPRLPSTA

10.71

-8.40

-5.24
P53169

MPTLPPRP

5.11

-13.47

-10.31

VPIMPTLP

10.53

-10.90

-7.74

SVPIMPTL

11.86

-8.31

-5.15
P53955

QRNPIPYP

11.82

-7.39

-4.23

RNPIPYPI

12.37

-6.67

-3.51

QNDPRSPL

13.59

-4.37

-1.21

 


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