ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1OOT-9.PDB
Scoring matrix: LSB3_1OOT-9_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.31
Foldx random average score for Saccharomyces cerevisiae: 12.591

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1602197
Proteins after disorder filtering: 4733
 Total fragments: 85467
Proteins after pattern filtering: 2233
 Total fragments: 13546
Proteins after MINT filtering: 71
 Total fragments: 789


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.31

-1.65

0.00
Best peptides

FDYISPRW

0.00

-7.75

-6.10
         
Interactors      
P38140

QPDLPPRK

5.02

-9.91

-8.26

MNIQPDLP

7.59

-7.39

-5.74

PDLPPRKI

9.09

-7.49

-5.84
Q06604

KPLLPTRP

5.10

-8.02

-6.37

GPRMPSRG

6.30

-9.84

-8.19

PPPLPTRR

6.57

-9.18

-7.53
P09119

MSAIPITP

9.41

-6.65

-5.00

TPTTSPVK

10.59

-2.65

-1.00

VPLTPTTS

10.68

-4.12

-2.47
P24814

PDIHPNLG

9.23

-6.42

-4.77

PNLGPQLW

10.40

-5.70

-4.05

NSTRPQMP

10.40

-7.50

-5.85
P25604

KPKSPHLK

7.91

-5.84

-4.19

KPPLPPPP

8.21

-6.14

-4.49

APSLPPKP

8.32

-5.39

-3.74
P40956

TPPLPRRR

6.60

-8.13

-6.48

PPLPRRRA

8.54

-5.47

-3.82

PKNVPFPF

10.32

-5.82

-4.17
P25623

ASDTPPLP

8.04

-6.52

-4.87

TPPLPPHA

10.18

-4.79

-3.14

LPVEPASP

10.32

-3.49

-1.84
P50942

RPCPPIRR

7.03

-8.71

-7.06

LPPVPALS

7.10

-7.75

-6.10

KPEKPPVV

7.59

-6.47

-4.82
Q04322

PPTLPPRR

6.65

-8.86

-7.21

SPPLPPRA

6.68

-8.02

-6.37

PTLPPRRI

9.01

-7.51

-5.86
P38266

QPPVPVRM

5.84

-8.82

-7.17

PPPKPFRH

6.18

-10.80

-9.15

VPILPPRN

6.20

-8.69

-7.04
P47043

PPQLPPKC

7.73

-6.25

-4.60

KKNKPNPP

9.52

-6.76

-5.11

SDPTSPQQ

9.67

-5.66

-4.01
P15891

QPPLPSRN

6.36

-9.61

-7.96

APPPPPRR

6.83

-8.80

-7.15

PPPPPRRA

7.45

-8.78

-7.13
P40341

PPPKPPLN

8.38

-8.60

-6.95

PPPPPPKP

9.32

-6.90

-5.25

KPPLNDPS

10.21

-3.53

-1.88
Q12134

QPVPSPMN

8.89

-4.75

-3.10

HQPVPSPM

11.33

-5.31

-3.66
P40494

DKSRPPRP

6.12

-9.45

-7.80

RPPRPPPK

8.15

-8.16

-6.51

RPPPKPLH

8.77

-4.52

-2.87
Q12200

PPSFPSRR

7.21

-8.59

-6.94

PSFPSRRC

8.23

-6.39

-4.74

LPCPVPRS

9.33

-6.65

-5.00
Q12344

SPPLPPRQ

6.77

-8.95

-7.30

SPKLPPRG

6.96

-7.60

-5.95

PPLPPRQN

11.41

-6.28

-4.63
P53189

TLQPSTIP

11.42

-3.64

-1.99
P53238

KPAGRPIP

10.19

-2.86

-1.21

IPPAPTHY

10.47

-4.53

-2.88

GRPIPPAP

10.89

-6.44

-4.79
P32660

DPTDPNRP

8.80

-6.97

-5.32

YDPTDPNR

8.81

-5.55

-3.90

DPNRPKVT

8.83

-5.21

-3.56
P33400

PQILPPLP

9.42

-5.94

-4.29

LPPLPVGI

9.91

-7.06

-5.41

PPNAPSYQ

10.30

-6.04

-4.39
P53901

LPPIPTRD

5.23

-9.24

-7.59

MRPIPPLP

6.42

-9.36

-7.71

QPPLPPIP

8.46

-6.06

-4.41
P38739

PNDPSTLA

10.17

-3.83

-2.18

SPFHDPIL

11.13

-1.61

0.04

PPNDPSTL

11.48

-4.19

-2.54
Q04749

LPVLPRRI

4.34

-8.54

-6.89

NPVFNPRK

7.56

-5.41

-3.76

PLPVLPRR

8.12

-8.48

-6.83
P04051

DRSLPHFP

9.76

-6.94

-5.29

LPHFPKNS

10.90

-5.10

-3.45

VNPAMLPG

12.15

-3.54

-1.89
P40325

QPPRPPRP

4.68

-9.54

-7.89

QPRPPPRP

6.27

-7.57

-5.92

PWTYPPRF

8.55

-8.45

-6.80
P47129

PPLLPPRN

6.45

-9.54

-7.89

PNPPPNRS

8.58

-8.28

-6.63

LPNRKPNP

8.70

-3.58

-1.93
P40453

PPDLPIRL

5.83

-8.91

-7.26

PPPLPPKI

7.90

-7.52

-5.87

MPTTPEIP

8.66

-5.70

-4.05
P40095

PPRSPNRP

7.45

-7.71

-6.06

NNRIPVLP

7.90

-7.16

-5.51

SPNRPTLS

8.33

-5.45

-3.80
Q12168

PPPLPPRA

6.06

-9.00

-7.35

PPPVPNRP

6.27

-9.28

-7.63

DPYFPQFR

7.52

-4.84

-3.19
P36125

SNDLPAGP

11.82

-5.11

-3.46
P53142

PLIEPTTT

12.52

-4.79

-3.14
P40528

LNDIPITP

8.59

-6.72

-5.07

IPITPSHD

9.41

-3.88

-2.23

DIPITPSH

11.85

-5.20

-3.55
P36123

TPKTPPRP

6.53

-7.65

-6.00

PDHFPSRS

7.57

-7.58

-5.93

RPGNPLYT

9.72

-4.96

-3.31
Q08412

LPTQPVRK

6.02

-9.22

-7.57

PPQLPTRT

6.51

-8.29

-6.64

EDVPPQLP

8.42

-6.99

-5.34
P32855

APTLPKRK

6.74

-9.44

-7.79

TNNAPTLP

10.86

-5.78

-4.13

YSNPSSSP

11.28

-2.63

-0.98
Q06409

KPRKTPRP

5.59

-7.67

-6.02

KTPRPPFP

7.33

-7.04

-5.39

FPTVPVVE

9.01

-4.52

-2.87
P32634

LPNSPILP

8.31

-5.42

-3.77

VPTEPTRY

8.46

-7.09

-5.44

KIPLEPLP

8.88

-5.56

-3.91
Q06833

RRPVPRRP

5.88

-10.80

-9.15

VPRRPSQP

8.41

-5.85

-4.20

FPVPPSAS

9.80

-2.69

-1.04
P50101

FPGSPIDK

11.19

-2.63

-0.98

VFPGSPID

11.85

-3.71

-2.06
P53118

PHDLPSHL

9.97

-5.20

-3.55

ENPHDLPS

12.25

-2.41

-0.76
Q12199

APATPPRH

5.76

-8.34

-6.69

NPNNPQCL

11.31

-3.35

-1.70

PNNPQCLH

11.50

-3.99

-2.34
P19158

LPDTPTMS

7.68

-5.95

-4.30

MTPVSPLG

8.23

-4.99

-3.34

GEYDPSLP

9.21

-5.02

-3.37
P38870

TPERPKRK

5.44

-10.08

-8.43

TPTTPERP

7.65

-6.40

-4.75

IHSTPKPP

10.29

-4.93

-3.28
P43638

HPDAPKLP

8.48

-5.84

-4.19

GRPIPPHP

9.86

-7.24

-5.59

PKLPSAFR

10.34

-4.28

-2.63
P53933

PPPLPNRQ

6.76

-9.55

-7.90

RPPPPPIP

9.18

-6.74

-5.09

NDLPMELP

9.62

-4.76

-3.11
P32790

PPAMPARP

6.10

-9.26

-7.61

PPIKPPRP

6.24

-9.72

-8.07

KPPRPTST

8.75

-6.19

-4.54
P40020

PPYLSPQN

7.99

-4.51

-2.86

SRVLPPLP

8.81

-6.94

-5.29

EPTSPTRQ

8.87

-6.72

-5.07
P38238

DPVQSPTN

9.57

-3.18

-1.53

LDPVQSPT

10.20

-4.88

-3.23

SPTNPPYK

10.92

-5.27

-3.62
P00175

LPNHPGGQ

10.82

-4.62

-2.97

TRFLPNHP

11.62

-5.93

-4.28
Q08229

NPTIPPRS

6.46

-8.28

-6.63

NDYNPTIP

8.96

-6.03

-4.38

LPSTPNED

10.55

-6.53

-4.88
P38930

FPDMVPKH

7.69

-4.85

-3.20

PDMVPKHP

9.29

-6.57

-4.92
Q12446

LPQLPNRN

5.53

-8.57

-6.92

APPPPPRR

6.83

-8.80

-7.15

KHSLPPLP

7.05

-6.93

-5.28
Q12211

RPKSGPRL

9.21

-7.53

-5.88

MQYNPPNP

9.49

-4.70

-3.05

KRPKSGPR

9.57

-6.77

-5.12
Q06116

SPELVPRS

8.75

-6.31

-4.66

EPNSPELV

9.04

-4.43

-2.78

KPFYPVTS

9.73

-4.18

-2.53
P33336

DRNLPSHP

10.37

-6.03

-4.38

LPSHPSSN

11.37

-5.78

-4.13

RNLPSHPS

11.66

-3.70

-2.05
P40041

KIPLSPPS

9.37

-5.88

-4.23

IPLSPPSS

11.32

-2.83

-1.18

GRTLPPVP

11.82

-5.80

-4.15
P38090

SPNDPDLT

10.24

-3.89

-2.24
Q06266

FPSSPYRT

6.47

-6.26

-4.61

YKQQPNCP

9.05

-5.31

-3.66

IPSSPAFP

9.40

-4.68

-3.03
Q00916

FKPRPPLS

5.89

-8.84

-7.19

KPRPPLSY

9.47

-4.10

-2.45

RLFKPRPP

9.92

-8.04

-6.39
P07269

LPNTPDFL

7.00

-5.49

-3.84

SDSGPQRP

8.99

-8.48

-6.83

PDEDPNLN

9.42

-6.77

-5.12
P40563

PSERPKRR

5.82

-10.52

-8.87

TPKVPERP

6.98

-6.98

-5.33

PPPVPKKP

8.22

-7.66

-6.01
P10566

IPAIPMDL

9.59

-4.82

-3.17

TRPIPAIP

9.80

-7.36

-5.71

PAIPMDLP

11.51

-4.73

-3.08
P38289

DPENPSFI

8.87

-4.88

-3.23

PENPSFIN

11.00

-4.12

-2.47

EDPENPSF

11.85

-4.39

-2.74
P47030

FPPEPSMS

8.08

-4.18

-2.53

PPEPSMSS

11.44

-2.93

-1.28

DEAFPPEP

11.77

-4.93

-3.28
P32863

LPDRPPNG

8.11

-5.94

-4.29

PDRPPNGI

11.43

-5.10

-3.45
P32862

FNYRPPNP

6.06

-6.95

-5.30

VPSTPSRS

6.57

-7.40

-5.75

QPQLPPPQ

9.58

-5.38

-3.73
P39743

NPLTSPVA

9.98

-2.87

-1.22
P31374

PDDLPPLK

6.87

-7.26

-5.61

KPGTPVFP

7.33

-6.12

-4.47

PERPSFRQ

7.73

-6.59

-4.94
P53169

MPTLPPRP

5.42

-8.96

-7.31

VPIMPTLP

8.03

-6.87

-5.22

ANSVPIMP

9.27

-7.37

-5.72
P53955

RNPIPYPI

9.17

-6.65

-5.00

QRNPIPYP

12.02

-3.74

-2.09

QNDPRSPL

12.41

-4.50

-2.85

 


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