ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1OOT-5.PDB
Scoring matrix: LSB3_1OOT-5_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.21
Foldx random average score for Saccharomyces cerevisiae: 18.576

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1416316
Proteins after disorder filtering: 4505
 Total fragments: 96340
Proteins after pattern filtering: 2302
 Total fragments: 20005
Proteins after MINT filtering: 73
 Total fragments: 1083


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.21

1.82

0.00
Best peptides

RRHYPPPDPF

0.00

-5.95

-7.77
         
Interactors      
P38140

PMNIQPDLPP

8.18

-6.69

-8.51

IQPDLPPRKI

10.53

-7.17

-8.99

MNIQPDLPPR

12.82

-6.18

-8.00
Q06604

RYSNIPSSKP

6.90

-7.36

-9.18

TMKNKPKPTP

9.09

-6.93

-8.75

PKPTPPSPPA

9.15

-4.69

-6.51
P09119

NSAQVPLTPT

12.09

-2.96

-4.78

QVPLTPTTSP

15.46

-3.69

-5.51

TPTTSPVKKS

18.18

-0.97

-2.79
P24814

NRLHPPDIHP

5.62

-6.20

-8.02

NNSTRPQMPS

12.28

-3.58

-5.40

RLHPPDIHPN

13.69

-4.79

-6.61
P25604

PHLKPPLPPP

6.51

-6.43

-8.25

PLPPPPPPQP

7.49

-8.11

-9.93

LKPPLPPPPP

7.56

-7.56

-9.38
P40956

ARFWNPKNVP

6.34

-6.63

-8.45

RFWNPKNVPF

11.86

-5.01

-6.83

FWNPKNVPFP

13.79

-4.83

-6.65
P25623

AQTFTPSEVP

7.69

-4.67

-6.49

ASDTPPLPPH

9.89

-4.28

-6.10

ISISQPPLQP

10.64

-5.56

-7.38
P50942

KLNVLPPPPP

5.29

-7.33

-9.15

ERHSTPKPLP

7.09

-8.63

-10.45

PLLSGPSPQP

7.70

-6.30

-8.12
Q04322

KNDQAPLDRP

7.70

-8.04

-9.86

SSSSTPPTLP

11.80

-5.40

-7.22

SSSTPPTLPP

12.24

-2.93

-4.75
P38266

QNFQPPPKPF

6.03

-6.13

-7.95

RNNVEPPPPP

6.04

-10.42

-12.24

ANIMPPPKPF

6.20

-7.93

-9.75
P47043

HLESKPPQLP

7.98

-7.86

-9.68

SKKNKPNPPP

8.23

-6.42

-8.24

LESKPPQLPP

10.28

-5.33

-7.15
P15891

KKSFTPSKSP

6.69

-4.61

-6.43

RSSAAPPPPP

8.49

-7.22

-9.04

SRSSAAPPPP

9.26

-7.24

-9.06
P40341

SRNIPPPPPP

4.62

-8.66

-10.48

RNIPPPPPPP

6.48

-9.35

-11.17

NSRNIPPPPP

10.04

-6.44

-8.26
Q12134

RSTHQPVPSP

9.88

-5.86

-7.68

THQPVPSPMN

12.33

-5.22

-7.04

HQPVPSPMNS

15.25

-1.19

-3.01
P40494

DKSRPPRPPP

5.46

-8.19

-10.01

SRPPRPPPKP

7.34

-8.86

-10.68

KDKSRPPRPP

10.51

-7.72

-9.54
Q12200

FGNELPCPVP

12.76

-3.16

-4.98

TDEVCPPSFP

12.85

-4.81

-6.63

GNELPCPVPR

13.33

-2.71

-4.53
Q12344

ATSTSPKLPP

12.34

-6.10

-7.92

PTTSSPPLPP

12.93

-6.77

-8.59

TTSSPPLPPR

13.32

-4.97

-6.79
P53189

TSTLQPSTIP

11.43

-3.43

-5.25
P53238

GRPIPPAPTH

8.18

-4.86

-6.68

QKPAGRPIPP

12.20

-7.07

-8.89

AGRPIPPAPT

13.62

-2.89

-4.71
P32660

GDGHAPMSPF

10.01

-3.82

-5.64

FDHYPPGYDP

11.55

-1.67

-3.49

HAPMSPFEDT

12.05

-5.57

-7.39
P33400

SYVQPPNAPS

9.69

-4.19

-6.01

SHSTSPQILP

10.12

-6.34

-8.16

PQILPPLPVG

10.78

-5.76

-7.58
P53901

NYNQPPLPPI

6.60

-5.28

-7.10

HNYNQPPLPP

8.37

-6.76

-8.58

MRPIPPLPTE

8.45

-4.75

-6.57
P38739

TLASPFHDPI

12.08

-5.54

-7.36

SPFHDPILPR

12.19

-2.43

-4.25

TAGSPPNDPS

12.82

-2.76

-4.58
Q04749

PLPVLPRRIS

10.63

-5.17

-6.99

FNPRKPTLST

11.29

-5.53

-7.35

NNSPLPVLPR

12.09

5.36

3.54
P04051

SLPHFPKNSK

12.62

-5.49

-7.31

FQDRSLPHFP

13.42

-7.62

-9.44

DRSLPHFPKN

14.83

-5.07

-6.89
P43603

GRFTAPTSPS

11.54

-5.03

-6.85

TAPTSPSTSS

14.76

-1.53

-3.35

QGRFTAPTSP

14.77

-3.58

-5.40
P40325

SQPRPPPRPQ

6.94

-8.13

-9.95

PWTYPPRFYC

8.66

-7.67

-9.49

PLYVQPGDPR

9.96

-5.26

-7.08
P47129

NRKPNPPPNR

9.13

-6.69

-8.51

RKPNPPPNRS

9.22

-6.20

-8.02

INNTLPNRKP

9.78

-5.50

-7.32
P40453

RLRKRPPPPP

3.34

-9.46

-11.28

LRKRPPPPPP

3.66

-8.42

-10.24

IRLRKRPPPP

8.56

-6.69

-8.51
P40095

IPVLPPPRSP

11.51

-3.88

-5.70

RIPVLPPPRS

12.43

-5.46

-7.28

TFPDSPSSSS

13.21

-1.99

-3.81
Q12168

NRGPPPLPPR

7.53

-6.56

-8.38

TNRGPPPLPP

8.30

-8.04

-9.86

NKVQHPVPKP

8.50

-8.66

-10.48
P36125

DLPAGPQGQR

10.38

-4.35

-6.17

YSNDLPAGPQ

13.35

-2.59

-4.41

TYSNDLPAGP

15.18

-4.07

-5.89
P32793

SLGHGPTHPS

10.68

-4.09

-5.91

HGPTHPSNMS

15.19

-0.82

-2.64

YSLGHGPTHP

17.89

-3.13

-4.95
P40528

SLNDIPITPS

11.76

-3.17

-4.99

DIPITPSHDN

15.74

-3.36

-5.18
P36123

PLYTTPKTPP

7.99

-7.86

-9.68

TSLFPPDHFP

9.54

-5.83

-7.65

ARPGNPLYTT

10.53

-5.77

-7.59
Q08412

KKKWQPLPPE

8.86

-6.68

-8.50

TKKKWQPLPP

10.58

-3.85

-5.67

KWQPLPPEPL

10.76

-7.84

-9.66
Q06697

GSSGGPRKDP

12.58

-5.39

-7.21

SSGGPRKDPI

15.75

-2.29

-4.11
Q06409

RKTPRPPFPF

5.57

-8.41

-10.23

KPRKTPRPPF

8.75

-7.75

-9.57

SSSHSPFSPF

8.80

-5.46

-7.28
P32634

PQEKIPLEPL

10.56

-6.77

-8.59

PLPPVPKAPS

11.45

-4.32

-6.14

SSVCYPLNLP

11.77

-4.77

-6.59
Q06833

NRRPVPRRPS

9.80

-5.18

-7.00

RRPSQPLNTL

10.09

-9.22

-11.04

NFPVPPSASN

10.48

-4.97

-6.79
P53118

ESVENPHDLP

12.41

-4.22

-6.04

PHDLPSHLGS

16.49

-2.49

-4.31

NPHDLPSHLG

16.64

-4.10

-5.92
Q12199

NNPNNPQCLH

11.42

-5.00

-6.82

RHICNNPNNP

11.95

-6.38

-8.20

AAPATPPRHI

12.25

-5.79

-7.61
P19158

PSSSSPSSPP

11.27

-4.09

-5.91

PGEYDPSLPD

13.61

-2.14

-3.96

YDPSLPDTPT

13.80

-1.82

-3.64
P38870

PIHSTPKPPP

10.68

-5.97

-7.79

HSTPKPPPND

14.39

-5.21

-7.03

IHSTPKPPPN

14.83

-6.71

-8.53
P43638

GRPIPPHPDA

9.47

-6.04

-7.86

NAHIPPTDAP

10.36

-5.31

-7.13

DAKGRPIPPH

10.43

-4.27

-6.09
P53933

RRRPPPPPIP

4.36

-10.96

-12.78

TRRRPPPPPI

5.31

-9.26

-11.08

AKRVAPPPLP

6.80

-8.18

-10.00
P50101

VFPGSPIDKS

11.96

-3.08

-4.90

IGTVFPGSPI

14.45

-2.50

-4.32

SIGTVFPGSP

15.50

-1.75

-3.57
P40020

SRVLPPLPFP

6.07

-8.09

-9.91

SFDRPPPLTP

7.04

-6.51

-8.33

RNCVNPHSIP

7.84

-8.75

-10.57
P38238

SSSLDPVQSP

12.79

-3.49

-5.31

DPVQSPTNPP

14.48

-4.85

-6.67

SLDPVQSPTN

16.47

-1.42

-3.24
P00175

ELVCPPYAPG

10.99

-4.49

-6.31

FLPNHPGGQD

12.27

-6.38

-8.20

PELVCPPYAP

12.32

-4.24

-6.06
Q08229

TNDYNPTIPP

9.40

-5.58

-7.40

YLTRPLPSTP

13.08

-5.65

-7.47

PLPSTPNEDS

13.63

-4.55

-6.37
P38930

FPDMVPKHPT

12.47

-2.22

-4.04

QAFPDMVPKH

17.30

-2.44

-4.26
Q12446

RRGPAPPPPP

4.77

-7.47

-9.29

TKHKAPPPPP

5.12

-8.69

-10.51

RLPAPPPPPR

6.03

-8.16

-9.98
P32855

LNYSNPSSSP

10.24

-5.52

-7.34

NYSNPSSSPN

13.76

-3.42

-5.24

GATNNAPTLP

14.86

-5.45

-7.27
Q12211

GMQYNPPNPT

7.47

-4.60

-6.42

HIDKRPKSGP

9.31

-6.67

-8.49

NGNPLPKEPR

12.98

-4.02

-5.84
Q06116

NLHSEPVEPF

7.46

-6.78

-8.60

VKPFYPVTSE

11.64

-3.94

-5.76

KNLHSEPVEP

12.10

-5.83

-7.65
P33336

NLPSHPSSNN

11.14

-4.00

-5.82

SITCDPEDYP

12.87

-3.52

-5.34

DRNLPSHPSS

14.34

0.80

-1.02
P40041

KIPLSPPSSS

13.29

-5.21

-7.03

IPLSPPSSSN

14.92

0.27

-1.55

PNGRTLPPVP

15.01

-8.37

-10.19
P38090

GIVCSPNDPD

14.90

-4.67

-6.49

CSPNDPDLTA

15.07

-1.29

-3.11

VCSPNDPDLT

17.87

-3.10

-4.92
Q06266

YRTVDPYSPP

6.39

-9.17

-10.99

MSSQFPSSPY

9.04

9.63

7.81

QQPNCPSSNY

10.19

-4.68

-6.50
Q00916

SRLFKPRPPL

7.48

-6.49

-8.31

LFKPRPPLSY

9.41

-7.09

-8.91

LSYKRPTDYP

11.24

-5.69

-7.51
P07269

ELPNTPDFLK

15.60

-6.22

-8.04

ASDSGPQRPK

16.50

-4.60

-6.42

DSELPNTPDF

16.79

-1.87

-3.69
P40563

PKRRAPPPVP

6.00

-8.51

-10.33

KRRAPPPVPK

10.68

-9.19

-11.01

KANSEPPTPA

10.69

-5.20

-7.02
P10566

PIPAIPMDLP

12.27

-6.65

-8.47

TRPIPAIPMD

12.82

-4.00

-5.82

PAIPMDLPDY

18.16

-1.87

-3.69
P38289

HMYDVPTNDP

11.59

-6.43

-8.25

EDPENPSFIN

16.29

-2.05

-3.87

VPTNDPSGIL

16.53

-2.15

-3.97
P47030

HNANNPLDKP

9.60

-6.61

-8.43

AFPPEPSMSS

12.91

-2.54

-4.36

DTETKPPRAP

13.65

-5.78

-7.60
P32790

SSAPAPLDPF

10.38

-4.76

-6.58

IKPPRPTSTT

12.57

-6.52

-8.34

DEEGPPPAMP

12.62

-4.31

-6.13
P32863

LPDRPPNGIG

14.67

-4.76

-6.58
P32862

DFNYRPPNPP

5.42

-6.65

-8.47

FNYRPPNPPA

8.24

-6.20

-8.02

LLGGQPQLPP

8.63

-7.29

-9.11
P39743

PNATIPEDNP

11.71

-4.69

-6.51

PAYSNPLTSP

11.89

-5.71

-7.53
P31374

RKTKPPPPLD

7.18

-9.76

-11.58

FRKTKPPPPL

8.18

-8.07

-9.89

LLEPTPDDLP

9.38

-7.77

-9.59
P53169

IMPTLPPRPY

7.40

-3.55

-5.37

TANSVPIMPT

11.94

-4.21

-6.03

SVPIMPTLPP

14.09

-4.73

-6.55
P53955

LAQRNPIPYP

9.36

-11.17

-12.99

QRNPIPYPID

10.78

-9.00

-10.82

SNQNDPRSPL

11.93

-6.83

-8.65

 


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