ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB3_1OOT-17.PDB
Scoring matrix: LSB3_1OOT-17_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 13.78
Foldx random average score for Saccharomyces cerevisiae: 13.710

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1499570
Proteins after disorder filtering: 4575
 Total fragments: 75738
Proteins after pattern filtering: 2019
 Total fragments: 7471
Proteins after MINT filtering: 70
 Total fragments: 409


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

13.78

2.09

0.00
Best peptides

RPFMMGYRR

0.00

-4.27

-6.36
         
Interactors      
P38140

PDLPPRKIM

8.33

-3.81

-5.90

IPPHPYPSS

10.47

-2.06

-4.15

PHPYPSSNQ

12.85

0.55

-1.54
Q06604

GPRMPSRGR

8.68

-3.61

-5.70

PLLPTRPNK

9.12

-2.64

-4.73

EKGPRMPSR

9.40

-2.23

-4.32
P09119

LTPTTSPVK

12.22

0.01

-2.08
P24814

HPPDIHPNL

11.55

-2.75

-4.84

IHPNLGPQL

12.16

-1.78

-3.87

PNLGPQLWL

12.39

-0.30

-2.39
P25604

PPKPKSPHL

8.30

-5.15

-7.24

PPLPPKPKS

9.73

-2.96

-5.05

LPPKPNTQL

9.86

-3.30

-5.39
P40956

TSTPPLPRR

8.73

-4.89

-6.98

TPPLPRRRA

10.88

-7.16

-9.25

PPLPRRRAT

11.60

-4.56

-6.65
P25623

LPPHATPKN

9.68

-3.20

-5.29

EPASPSISL

10.89

-0.45

-2.54

EVPPSTPQQ

11.42

-0.22

-2.31
Q12532

PFKPYINGG

13.24

-0.80

-2.89
Q04322

STPPTLPPR

13.60

-0.63

-2.72
P38266

PPPKPFRHG

6.47

-3.93

-6.02

PPKPFRRSQ

7.25

-3.04

-5.13

FLPPPKPFR

7.57

-5.28

-7.37
P47043

ASDPTSPQQ

12.06

-0.30

-2.39

PQLPPKCSS

12.17

-0.57

-2.66

PTSPQQNSK

12.24

-0.15

-2.24
P15891

RATPEKKPK

10.79

-2.41

-4.50

AAQPPLPSR

10.90

-2.47

-4.56

ATPEKKPKE

11.48

-1.06

-3.15
P40341

PPPPPKPPL

11.82

-4.06

-6.15

LNDPSNPVS

13.43

-0.77

-2.86
Q12134

PVPSPMNSQ

12.92

-0.33

-2.42

HQPVPSPMN

13.48

1.56

-0.53
P40494

PRPPPKPLH

11.10

-1.57

-3.66

PNMMPVTHV

13.24

-3.31

-5.40
Q12200

PPSFPSRRC

9.21

-5.03

-7.12

VCPPSFPSR

10.40

-2.34

-4.43

SCPHLKPLK

11.46

-1.74

-3.83
Q12344

PKLPPRGKQ

10.05

-2.92

-5.01

PPLPPRQNV

10.90

-4.68

-6.77

TSSPPLPPR

12.75

-2.11

-4.20
P53238

RPIPPAPTH

9.42

-2.67

-4.76

PPAPTHYNN

9.98

-0.27

-2.36

IPPAPTHYN

11.21

-2.44

-4.53
P32660

GYDPTDPNR

10.60

-2.08

-4.17

DPNRPKVTK

10.90

-2.55

-4.64

PTDPNRPKV

12.01

-0.66

-2.75
P33400

QILPPLPVG

11.54

-3.31

-5.40

PPNAPSYQS

11.55

-0.78

-2.87

VQPPNAPSY

12.66

-2.07

-4.16
P53901

PNSHPHPSG

10.15

-0.50

-2.59

RPIPPLPTE

10.17

-3.51

-5.60

PPLPPIPTR

10.71

-3.39

-5.48
P38739

ASPFHDPIL

12.40

-0.62

-2.71

PPNDPSTLA

12.72

0.07

-2.02

TSPSTAPSS

13.15

1.64

-0.45
Q04749

SPLPVLPRR

8.43

-5.67

-7.76

TNPVFNPRK

9.47

-4.52

-6.61

LPVLPRRIS

11.45

-4.33

-6.42
P04051

RSLPHFPKN

9.47

-1.25

-3.34

LPHFPKNSK

9.71

-3.59

-5.68

VNPAMLPGS

13.58

-0.31

-2.40
P43603

FTAPTSPST

11.18

-0.88

-2.97

APTSPSTSS

12.64

0.51

-1.58

RFTAPTSPS

13.17

1.00

-1.09
P40325

RPPRPAANL

7.22

-4.62

-6.71

YVQPGDPRL

8.89

-4.64

-6.73

PPRPPRPAA

10.55

-1.90

-3.99
P47129

PNPPPNRSQ

10.05

-3.09

-5.18

PLLPPRNTM

11.68

-2.43

-4.52

NTLPNRKPN

13.49

-0.84

-2.93
P40453

PDLPIRLRK

7.65

-5.54

-7.63

WKPPDLPIR

8.99

-3.79

-5.88

DCPRCGPTA

10.45

-2.10

-4.19
P40095

LPPPRSPNR

7.35

-6.03

-8.12

FPDSPSSSS

10.65

-0.58

-2.67

PDSPSSSSL

11.68

-0.44

-2.53
Q12168

DPYFPQFRS

9.92

-4.26

-6.35

PPVPNRPGG

10.14

-3.27

-5.36

PPLPPRANV

10.86

-4.02

-6.11
P36125

PAGPQGQRR

9.05

-2.99

-5.08

NDLPAGPQG

9.90

-0.70

-2.79

LPAGPQGQR

11.40

-2.95

-5.04
P53142

PLIEPTTTN

13.64

-1.80

-3.89
P36123

RSQPSDPKL

9.00

-1.73

-3.82

FPPDHFPSR

9.00

-2.73

-4.82

PDHFPSRSQ

10.57

0.17

-1.92
Q08412

LPTQPVRKN

11.13

-3.19

-5.28

PQLPTRTKS

11.53

-0.51

-2.60

DVPPQLPTR

11.89

-1.29

-3.38
P32793

GPTHPSNMS

12.17

-1.88

-3.97

GHGPTHPSN

12.79

0.24

-1.85

PTHPSNMSN

12.89

0.91

-1.18
Q06409

TPRPPFPFF

9.96

-4.78

-6.87

TPRNPDPYG

11.28

-0.95

-3.04

SHSPFSPFN

12.52

-0.11

-2.20
P32634

LPIVPNPNL

8.83

-3.86

-5.95

PPVPKAPSR

9.06

-2.64

-4.73

VPTEPTRYN

9.92

-2.06

-4.15
Q06833

RPVPRRPSQ

6.12

-4.88

-6.97

FPVPPSASN

8.93

-3.01

-5.10

RRPVPRRPS

10.15

-1.99

-4.08
P50101

FPGSPIDKS

11.98

-0.69

-2.78

PGSPIDKSI

12.27

-3.14

-5.23

TVFPGSPID

12.73

-1.25

-3.34
P53118

ENPHDLPSH

10.68

-0.76

-2.85
Q12199

PATPPRHIC

10.95

-2.87

-4.96

PNNPQCLHC

11.39

-1.32

-3.41

CNNPNNPQC

12.46

-1.47

-3.56
P19158

SMTPVSPLG

11.45

-0.99

-3.08

PSSPPSSSS

12.25

0.47

-1.62

PSLPDTPTM

12.25

-0.76

-2.85
P38870

TPERPKRKS

8.36

-3.77

-5.86

PTTPERPKR

9.27

-2.47

-4.56

TPTTPERPK

12.24

-2.74

-4.83
P43638

PKLPSAFRK

9.65

-3.83

-5.92

PPHPDAPKL

10.50

-2.39

-4.48

PDAPKLPSA

11.03

-1.28

-3.37
P53933

VAPPPLPNR

10.48

-3.34

-5.43

PPPPPIPST

12.22

-2.35

-4.44

PPPIPSTQK

13.03

-1.80

-3.89
P32790

APAPLDPFK

10.34

-1.69

-3.78

PIKPPRPTS

10.88

-1.88

-3.97

APLDPFKTG

11.42

-0.91

-3.00
P40020

PPLTPEKNL

9.73

-3.46

-5.55

YLTPESPLN

10.78

-2.43

-4.52

RPPPLTPEK

10.86

-0.95

-3.04
P38238

LDPVQSPTN

12.20

-1.60

-3.69
P00175

RFLPNHPGG

9.71

-2.12

-4.21

LPNHPGGQD

10.10

-2.06

-4.15

LVCPPYAPG

11.93

-2.20

-4.29
Q08229

RPLPSTPNE

8.83

-2.04

-4.13

TPVQPGGHY

8.86

-2.38

-4.47

PVQPGGHYK

9.76

-2.28

-4.37
P40528

NDIPITPSH

11.03

-0.63

-2.72

PITPSHDNN

12.56

-1.47

-3.56
Q12446

RPLPQLPNR

6.69

-5.00

-7.09

PPPPPRASR

8.34

-5.10

-7.19

LPDPPQHNS

8.90

-3.06

-5.15
P32855

NNAPTLPKR

10.86

-1.35

-3.44

PSSSPNSLG

13.19

0.56

-1.53
Q12211

KRPKSGPRL

6.34

-4.05

-6.14

DKRPKSGPR

13.13

-0.66

-2.75
Q06116

PELVPRSST

12.89

-1.43

-3.52

HSEPVEPFS

12.93

1.28

-0.81

NSPELVPRS

13.39

-2.63

-4.72
P33336

RNLPSHPSS

9.34

-0.93

-3.02

LPSHPSSNN

9.96

-3.26

-5.35

PSHPSSNNM

12.18

-1.36

-3.45
P40041

PLSPPSSSN

12.31

-2.23

-4.32
P50942

RPCPPIRRK

5.32

-7.80

-9.89

PPPPTSRHN

8.53

-3.63

-5.72

PCPPIRRKS

9.15

-3.50

-5.59
Q06266

PYSPPNYKQ

10.57

-1.86

-3.95

SPAFPGQLA

11.00

-0.33

-2.42

SQFPSSPYR

11.83

-1.00

-3.09
Q00916

RLFKPRPPL

8.57

-5.17

-7.26

PRPPLSYKR

9.11

-2.12

-4.21

KPRPPLSYK

9.58

-2.36

-4.45
P07269

LPNTPDFLK

9.21

-2.52

-4.61

DSGPQRPKR

9.68

-2.13

-4.22

PNTPDFLKN

12.48

-0.97

-3.06
P40563

PSERPKRRA

7.72

-4.46

-6.55

RAPPPVPKK

10.75

-1.66

-3.75

NSQPQGPSD

11.65

0.46

-1.63
P10566

RPIPAIPMD

10.09

-2.16

-4.25
P38289

DVPTNDPSG

10.83

-0.87

-2.96

DPENPSFIN

12.71

0.14

-1.95

PTNDPSGIL

13.35

0.48

-1.61
P47030

FPPEPSMSS

8.10

-2.10

-4.19

EAFPPEPSM

10.02

-0.83

-2.92
P32863

PDRPPNGIG

10.84

-2.05

-4.14
P32862

VPSTPSRSN

10.28

-2.76

-4.85

NTVPSTPSR

11.18

-1.46

-3.55

MNPSNSPNS

11.31

-0.86

-2.95
P31374

SPERPSFRQ

8.35

-4.90

-6.99

NISPERPSF

9.98

-3.84

-5.93

KPPPPLDFE

11.41

-0.60

-2.69
P53169

SPAQPSASL

11.73

-1.84

-3.93

PIMPTLPPR

12.12

-2.74

-4.83

NSVPIMPTL

12.66

-0.71

-2.80
P53955

RNPIPYPID

11.86

-0.90

-2.99

 


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