ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKA-26.PDB
Scoring matrix: LSB1_1CKA-26_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.85
Foldx random average score for Saccharomyces cerevisiae: 11.531

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 1447920
Proteins after disorder filtering: 4380
 Total fragments: 70904
Proteins after pattern filtering: 2224
 Total fragments: 16555
Proteins after MINT filtering: 27
 Total fragments: 549


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.85

-1.65

0.00

Best peptides

SRRPKRFPK

0.00

-2.37

-0.72

         
Interactors      
Q06604

PTPPSPPAK

6.02

-6.95

-5.30

PLLPTRPNK

6.39

-6.11

-4.46

SSPPPLPTR

7.51

-6.81

-5.16

P53120

SYEPECPVA

10.82

-4.83

-3.18

TRSYEPECP

11.49

-3.19

-1.54

RSYEPECPV

11.50

-3.93

-2.28

Q04322

STPPTLPPR

7.44

-6.89

-5.24

QAPLDRPQL

7.69

-5.49

-3.84

TSPPLPPRA

8.17

-6.70

-5.05

Q12168

RGPPPLPPR

7.50

-7.13

-5.48

IPPPVPNRP

7.65

-5.57

-3.92

PLPPRANVQ

7.82

-4.83

-3.18

P53169

NSVPIMPTL

7.67

-5.91

-4.26

PIMPTLPPR

8.12

-6.69

-5.04

MPTLPPRPY

10.40

-4.55

-2.90

Q12344

SPKLPPRGK

4.54

-5.57

-3.92

SSPPLPPRQ

6.50

-6.54

-4.89

SPPLPPRQN

8.54

-5.44

-3.79

Q07533

SSMPNSPKK

6.04

-5.44

-3.79

PKSPKAYPK

6.20

-4.09

-2.44

PPVPSRYSD

7.74

-2.93

-1.28

P53238

AGRPIPPAP

8.15

-6.74

-5.09

RPIPPAPTH

8.95

-5.01

-3.36

GRPIPPAPT

9.89

-5.26

-3.61

P08417

ELMLPENEP

9.48

-3.98

-2.33

P39521

PHVPDRPPS

8.31

-7.54

-5.89

HVPDRPPSQ

8.35

-5.35

-3.70

DAQPKPKPA

8.60

-6.16

-4.51

P04050

PPPPVRPSI

6.27

-6.84

-5.19

VPPPPVRPS

8.13

-6.40

-4.75

PGSPAYSPK

8.68

-2.90

-1.25

P40453

PDLPIRLRK

4.97

-6.39

-4.74

EIPPPLPPK

5.08

-6.57

-4.92

KPPDLPIRL

6.41

-6.08

-4.43

P19812

EPRPRRIPP

4.35

-7.16

-5.51

PQNPPPILQ

8.02

-5.36

-3.71

HSPIFRPGN

8.52

-7.40

-5.75

Q03780

RSRPPPPPM

4.36

-7.46

-5.81

PPPPPMDMK

5.71

-5.13

-3.48

RPPPPPMDM

6.01

-8.34

-6.69

P48582

MAAPPVPPK

6.31

-5.97

-4.32

SPAPPLPPL

7.16

-6.18

-4.53

PPLPPLDSK

7.82

-4.18

-2.53

P53933

RRRPPPPPI

5.28

-6.89

-5.24

APPPLPNRQ

6.66

-4.78

-3.13

RPPPPPIPS

7.03

-6.99

-5.34

Q08229

PVQPGGHYK

7.73

-2.81

-1.16

NPTIPPRSK

8.53

-3.81

-2.16

DYNPTIPPR

8.64

-6.18

-4.53

P33338

PTPPVVAEP

10.52

-5.46

-3.81

PARTPARTP

10.77

-4.34

-2.69

LSWSGPLTP

11.29

-3.58

-1.93

P43582

TTWPRPKGP

8.21

-5.85

-4.20

WPRPKGPPP

8.88

-6.24

-4.59

SNPPQVPSG

9.32

-7.55

-5.90

P40483

PSVPPRNYF

6.70

-3.48

-1.83

ASKPSVPPR

8.08

-6.19

-4.54

SKPSVPPRN

9.87

-4.94

-3.29

P39940

DDPRLPSSL

9.28

-4.08

-2.43

TWDDPRLPS

9.32

-3.00

-1.35

TTWDDPRLP

9.64

-4.48

-2.83

P38266

PPKPFRHGL

4.62

-5.41

-3.76

PPKPFRRSQ

5.17

-6.44

-4.79

KKPPVVPKK

5.39

-6.53

-4.88

Q04659

KDPTVPNGL

8.45

-4.06

-2.41

P40563

RAPPPVPKK

5.47

-6.53

-4.88

RRAPPPVPK

6.22

-5.83

-4.18

APPPVPKKP

8.30

-7.17

-5.52

P00812

LNKDVPHCP

8.98

-2.67

-1.02

VDPLYIPAT

9.68

-6.11

-4.46

KDVPHCPES

9.85

-4.89

-3.24

Q04195

PSEPIIINL

7.68

-7.03

-5.38

SHPSEPIII

8.25

-5.03

-3.38

SSHPSEPII

8.70

-4.91

-3.26

Q12446

RPVPPPPPM

5.96

-6.60

-4.95

PPPPPRRGP

6.42

-7.04

-5.39

PPPPHRHVT

6.58

-5.25

-3.60

 


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