ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKA-19.PDB
Scoring matrix: LSB1_1CKA-19_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.1
Foldx random average score for Saccharomyces cerevisiae: 14.541

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1556448
Proteins after disorder filtering: 4603
 Total fragments: 76067
Proteins after pattern filtering: 2215
 Total fragments: 11125
Proteins after MINT filtering: 28
 Total fragments: 334


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.10

0.25

0.00

Best peptides

RRSPYGRWM

0.00

0.42

0.17

         
Interactors      
Q06604

PPSPPAKRI

6.38

-9.11

-9.36

GPRMPSRGR

10.14

-7.20

-7.45

PPLPTRRDH

10.16

-6.79

-7.04

P53120

RSYEPECPV

13.84

-4.64

-4.89

Q04322

DQAPLDRPQ

10.76

-5.51

-5.76

GNATPSKSP

13.89

-5.50

-5.75

SSTPPTLPP

14.44

-6.90

-7.15

Q12168

PPLPPRANV

9.56

-9.20

-9.45

NDDPYFPQF

10.31

-5.12

-5.37

PPVPNRPGG

10.70

-8.16

-8.41

P53169

SPAQPSASL

12.29

-6.02

-6.27

NSVPIMPTL

12.57

-4.16

-4.41

PIMPTLPPR

12.74

-6.43

-6.68

Q12344

PKLPPRGKQ

8.44

-7.01

-7.26

PPLPPRQNV

9.62

-9.26

-9.51

TSSPPLPPR

11.38

-6.73

-6.98

Q07533

PHFPYGTWK

8.46

-2.58

-2.83

IPPVPSRYS

9.20

-5.74

-5.99

PKSPKAYPK

9.77

-5.83

-6.08

P53238

RPIPPAPTH

10.83

-6.83

-7.08

PPAPTHYNN

11.97

-8.00

-8.25

IPPAPTHYN

12.99

-5.74

-5.99

P08417

PENEPGSSI

9.97

-2.71

-2.96

LMLPENEPG

13.21

-4.63

-4.88

MLPENEPGS

13.93

-2.19

-2.44

P39521

PDRPPSQLS

10.51

-5.55

-5.80

TPHVPDRPP

10.68

-9.82

-10.07

VDAQPKPKP

12.31

-5.91

-6.16

P04050

PPVRPSISF

9.10

-6.52

-6.77

PPPPVRPSI

9.77

-7.07

-7.32

APTSPGFGV

10.85

-4.32

-4.57

P40453

PDLPIRLRK

6.52

-6.87

-7.12

SWKPPDLPI

10.29

-7.24

-7.49

VPEPPSWKP

11.30

-8.81

-9.06

P19812

DHSPIFRPG

11.29

-5.39

-5.64

PIFRPGNIF

11.57

-6.87

-7.12

EPRPRRIPP

11.84

-8.31

-8.56

Q03780

PRSPNRNAH

10.36

-5.08

-5.33

PPRSPNRNA

10.54

-7.53

-7.78

PPPPMDMKS

10.66

-8.48

-8.73

P48582

RNTPPQPSL

8.31

-8.35

-8.60

PPVPPKQSQ

9.33

-7.95

-8.20

PPQPSLLDI

9.96

-6.20

-6.45

P53933

PPLPNRQLP

9.55

-8.79

-9.04

PPPLPNRQL

10.49

-9.81

-10.06

PPPIPSTQK

11.00

-6.85

-7.10

Q08229

TPVQPGGHY

8.03

-5.41

-5.66

PVQPGGHYK

11.18

-5.23

-5.48

PSTPNEDSR

11.36

-4.87

-5.12

P33338

ARTPARTPT

12.94

-3.69

-3.94

TPTPPVVAE

14.01

-5.90

-6.15

PARTPARTP

14.03

-6.18

-6.43

P32893

NGTIPNSPL

12.95

-6.00

-6.25

Q12446

PPPPPHRHV

7.55

-9.91

-10.16

PPPPPRRGP

9.04

-10.79

-11.04

RPLPQLPNR

9.50

-7.87

-8.12

P40483

PSVPPRNYF

11.12

-7.35

-7.60

KDAPASKPS

11.20

-3.73

-3.98

KPSVPPRNY

11.85

-9.91

-10.16

P39940

PRLPSSLDQ

9.91

-3.77

-4.02

WDDPRLPSS

11.42

-5.34

-5.59

PSSSPHSQA

12.82

-3.03

-3.28

P38266

PPKPFRRSQ

7.64

-8.00

-8.25

PRPPPSRSS

8.81

-6.92

-7.17

IMPPPKPFR

8.94

-6.93

-7.18

Q04659

PTVPNGLDG

9.94

-4.62

-4.87

DPTVPNGLD

12.66

-5.54

-5.79

P40563

PSERPKRRA

9.46

-6.54

-6.79

GMVNPGQLP

11.13

-6.10

-6.35

PPTPAGTPN

11.50

-6.05

-6.30

P00812

PHCPESLKW

10.37

-2.75

-3.00

VPHCPESLK

12.53

-5.86

-6.11

PLYIPATGT

13.16

-4.96

-5.21

Q04195

PSEPIIINL

10.94

-7.09

-7.34

GNEPIQFPF

11.31

-5.66

-5.91

PTLPQNVPI

11.93

-5.38

-5.63

P43582

WPRPKGPPP

9.84

-8.11

-8.36

TWPRPKGPP

12.94

-6.50

-6.75

KSNPPQVPS

13.29

-5.55

-5.80

 


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