ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: LSB1_1CKA-15.PDB
Scoring matrix: LSB1_1CKA-15_mat
Uniprot code: P53281
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.9
Foldx random average score for Saccharomyces cerevisiae: 12.555

Available information for P53281 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 53
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1408151
Proteins after disorder filtering: 4077
 Total fragments: 38408
Proteins after pattern filtering: 1760
 Total fragments: 6322
Proteins after MINT filtering: 26
 Total fragments: 212


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.90

-1.14

0.00

Best peptides

RRRIIKKKV

0.00

-1.25

-0.11

         
Interactors      
Q06604

MKNKPKPTP

9.50

-4.27

-3.13

PTRPNKAEV

9.84

-2.88

-1.74

LLPTRPNKA

10.02

-4.56

-3.42

P53120

YEPECPVAY

11.32

-4.05

-2.91

RSYEPECPV

11.93

-3.81

-2.67

TRSYEPECP

12.46

-3.36

-2.22

Q04322

TPPTLPPRR

10.97

-6.62

-5.48

TPSKSPTSA

12.40

-4.69

-3.55

NDQAPLDRP

12.47

-2.85

-1.71

P19812

RPRRIPPTD

8.81

-6.64

-5.50

PRRIPPTDE

11.07

-3.77

-2.63

HSPIFRPGN

11.21

-2.18

-1.04

P53169

NSVPIMPTL

10.34

-3.42

-2.28

MPTLPPRPY

11.78

-6.08

-4.94

PIMPTLPPR

12.30

-6.25

-5.11

Q12344

PPLPPRQNV

11.35

-6.32

-5.18

SPKLPPRGK

11.53

-5.93

-4.79

Q07533

MPNSPKKPV

8.43

-3.35

-2.21

PPLPDLDNM

10.58

-6.47

-5.33

APNLPLASH

10.66

-5.45

-4.31

P53238

RPIPPAPTH

11.71

-7.66

-6.52

P39521

AQPKPKPAQ

10.57

-1.69

-0.55

VDAQPKPKP

11.10

-1.85

-0.71

VPDRPPSQL

12.03

-5.98

-4.84

P04050

LPVPPPPVR

10.78

-7.86

-6.72

PPPVRPSIS

11.37

-5.48

-4.34

CLPVPPPPV

11.43

-5.25

-4.11

P40453

WKPPDLPIR

9.27

-5.17

-4.03

PPDLPIRLR

10.00

-7.46

-6.32

PPPVSMPTT

10.07

-6.27

-5.13

Q12168

QHPVPKPNI

9.95

-3.97

-2.83

HPVPKPNID

10.83

-2.16

-1.02

PPLPPRANV

11.19

-5.50

-4.36

Q03780

PPPPPMDMK

9.09

-7.53

-6.39

RPPPPPMDM

9.50

-9.64

-8.50

IPPRSPNRN

11.81

-5.47

-4.33

P48582

PPVPPKQSQ

10.24

-4.90

-3.76

PPLPPLDSK

10.36

-7.21

-6.07

GPGIPPRTY

11.36

-4.94

-3.80

Q04659

KDPTVPNGL

11.76

-3.46

-2.32

P53933

YNDLPMELP

10.16

-4.42

-3.28

RRPPPPPIP

10.51

-7.97

-6.83

PPPIPSTQK

11.48

-4.80

-3.66

Q08229

NPTIPPRSK

8.67

-4.56

-3.42

RPLPSTPNE

11.43

-4.43

-3.29

YNPTIPPRS

11.44

-5.20

-4.06

P33338

TPTPTPPVV

10.71

-3.73

-2.59

RTPTPTPPV

11.14

-4.33

-3.19

TPARTPART

11.61

-5.04

-3.90

P43582

RPKGPPPGV

9.98

-6.98

-5.84

NPPQVPSGW

10.33

-3.73

-2.59

TWPRPKGPP

12.55

-2.47

-1.33

P39940

WDDPRLPSS

12.45

-2.22

-1.08

P38266

FLPPPKPFR

7.09

-5.98

-4.84

KPPVVPKKK

7.32

-6.53

-5.39

FQPPPKPFR

7.96

-5.79

-4.65

P40483

KPSVPPRNY

10.18

-6.79

-5.65

DAPASKPSV

10.57

-1.87

-0.73

P40563

PSERPKRRA

9.35

-3.66

-2.52

RAPPPVPKK

9.71

-6.51

-5.37

PPPVPKKPS

10.35

-5.21

-4.07

P00812

DPLYIPATG

12.10

-3.94

-2.80

VPHCPESLK

12.41

-4.71

-3.57

Q04195

HPSEPIIIN

9.83

-4.27

-3.13

VLPTLPQNV

10.33

-3.06

-1.92

NSTPVLPTL

10.77

-2.57

-1.43

Q12446

RPLPQLPNR

7.89

-9.29

-8.15

QPAVPLPQN

10.40

-4.46

-3.32

LPPASPEVR

10.41

-5.99

-4.85

 


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