ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-7.PDB
Scoring matrix: HSE1_1SEM-7_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 16.65
Foldx random average score for Saccharomyces cerevisiae: 13.621

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1471020
Proteins after disorder filtering: 4709
 Total fragments: 75769
Proteins after pattern filtering: 2136
 Total fragments: 11384
Proteins after MINT filtering: 29
 Total fragments: 428


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

16.65

-0.63

0.00

Best peptides

IDPRSPKY

0.00

-3.37

-2.74

         
Interactors      
Q06604

LPTRPNKA

6.28

-7.16

-6.53

PPPLPTRR

7.72

-9.87

-9.24

PPSPPAKR

8.96

-6.05

-5.42

Q06108

TDPRSPYY

4.66

-4.69

-4.06

DPPPQPRR

8.69

-6.10

-5.47

PPPQPRRL

9.31

-7.50

-6.87

P40073

YPQQQPSH

12.66

-3.82

-3.19

P25604

PKPKSPHL

9.06

-6.56

-5.93

TPPLPPKP

9.43

-6.41

-5.78

APSLPPKP

9.57

-6.83

-6.20

P40325

QPPRPPRP

7.59

-8.67

-8.04

RPPRPAAN

8.88

-6.36

-5.73

SQPRPPPR

9.65

-6.58

-5.95

Q06412

NSPKSPRD

9.19

-6.56

-5.93

FSPNSPKS

9.63

-3.20

-2.57

PPPPPLLY

9.74

-6.34

-5.71

Q66RC5

IPDNPGRL

7.58

-7.38

-6.75

PDNPGRLL

11.33

-5.22

-4.59

P36037

PLKLPINV

11.34

-6.17

-5.54

PPLKLPIN

11.42

-6.15

-5.52

KPPLKLPI

13.29

-6.45

-5.82

P40341

PPPPPPKP

10.08

-6.55

-5.92

PPPKPPLN

10.13

-6.81

-6.18

IPPPPPPP

10.29

-5.55

-4.92

P40343

SDPPYPKE

10.09

-4.03

-3.40

SPQPQPIH

11.46

-3.95

-3.32

ELAPSDPP

12.67

-3.61

-2.98

P53238

IPPAPTHY

8.33

-5.66

-5.03

RPIPPAPT

12.02

-5.00

-4.37

PAGRPIPP

12.20

-6.14

-5.51

P04051

SLPHFPKN

9.62

-3.42

-2.79

RSLPHFPK

10.57

-4.47

-3.84

LPHFPKNS

11.35

-3.51

-2.88

P48524

PLLRPQRS

7.76

-9.32

-8.69

PPKRKPLL

7.89

-7.20

-6.57

PKRKPLLR

9.78

-8.29

-7.66

P40453

PPPLPPKI

7.31

-7.53

-6.90

PPDLPIRL

8.37

-9.01

-8.38

IPPPLPPK

9.19

-4.39

-3.76

Q06697

GGPRKDPI

11.94

-4.16

-3.53

P38753

PVMPPQRQ

11.11

-7.08

-6.45

TPVMPPQR

11.20

-4.99

-4.36

PVPGPALY

11.34

-4.55

-3.92

P38351

VPQLPPKL

9.01

-6.29

-5.66

PQLPPKLL

11.09

-5.66

-5.03

LPVPQLPP

12.12

-5.12

-4.49

Q06524

PTVPNELL

11.83

-5.09

-4.46

P40020

LPPLPFPL

9.15

-6.35

-5.72

LTPESPLN

9.25

-4.31

-3.68

PPLPFPLY

9.65

-5.52

-4.89

P36041

MPPPPGLV

8.73

-6.75

-6.12

MPPLPQGF

8.74

-6.70

-6.07

FFPMHPNF

9.21

-5.34

-4.71

Q04439

IPTPPQNR

9.56

-5.51

-4.88

PPPPSSKP

9.63

-3.86

-3.23

PTPPQNRD

9.68

-5.93

-5.30

Q03497

IPSRPAPK

6.57

-6.56

-5.93

LPPIPPTK

9.55

-5.87

-5.24

FPSKNPLK

10.28

-5.99

-5.36

P40041

IPLSPPSS

12.15

-4.49

-3.86

KIPLSPPS

12.88

-5.83

-5.20

PLSPPSSS

13.61

-4.27

-3.64

Q03973

PTHAPVPI

12.70

-4.09

-3.46

P10566

IPAIPMDL

9.46

-5.79

-5.16

RPIPAIPM

11.72

-4.50

-3.87

IPMDLPDY

11.73

-1.27

-0.64

Q03935

IQPPLPNL

9.31

-4.63

-4.00

QPPLPNLM

9.51

-7.78

-7.15

INPPLPNG

9.80

-3.41

-2.78

O13527

IHPRGIPG

9.41

-4.28

-3.65

PLNPKGKK

9.69

-5.50

-4.87

IPYTPYQM

9.71

-6.07

-5.44

P53901

LPPIPTRD

7.78

-8.17

-7.54

MRPIPPLP

8.52

-7.81

-7.18

MAMRPIPP

9.37

-8.25

-7.62

Q12446

LPQLPNRN

8.05

-8.76

-8.13

APPPPPRR

8.57

-8.15

-7.52

LPPLPNQF

8.86

-5.51

-4.88

 


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