ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-28.PDB
Scoring matrix: HSE1_1SEM-28_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.15
Foldx random average score for Saccharomyces cerevisiae: 18.046

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1368281
Proteins after disorder filtering: 4213
 Total fragments: 54463
Proteins after pattern filtering: 1988
 Total fragments: 9212
Proteins after MINT filtering: 27
 Total fragments: 312


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.15

3.31

0.00

Best peptides

RRPRRRKRKF

0.00

-6.77

-10.08

         
Interactors      
Q06604

LPTRPNKAEV

11.70

-10.17

-13.48

FEKGPRMPSR

12.56

-9.04

-12.35

KPLLPTRPNK

13.19

-10.86

-14.17

Q06108

TDPRSPYYIN

10.76

-8.41

-11.72

DPPPQPRRLS

13.44

-8.89

-12.20

DPRSPYYINM

14.06

-8.17

-11.48

P40073

FDGYPQQQPS

16.24

-5.70

-9.01

DGYPQQQPSH

18.03

-5.16

-8.47

P25604

TPPLPPKPKS

10.43

-7.95

-11.26

PPPPPPQPAS

12.24

-8.82

-12.13

PPKPNTQLQQ

15.02

-7.22

-10.53

P40325

RPPRPAANLA

9.00

-10.08

-13.39

QPPRPPRPAA

9.10

-11.42

-14.73

PPPRPQQNPS

13.16

-9.16

-12.47

Q06412

RPPPPPPLLY

11.77

-9.08

-12.39

RRPPPPPPLL

12.22

-8.54

-11.85

FFTKPPPPLS

13.43

-6.71

-10.02

Q66RC5

IPDNPGRLLS

14.20

-7.06

-10.37

SPLIPDNPGR

15.51

-7.90

-11.21

P36037

PPLKLPINVS

14.88

-7.32

-10.63

KPPLKLPINV

17.93

-7.77

-11.08

GKPPLKLPIN

17.96

-6.65

-9.96

P40341

PPPPPKPPLN

16.11

-8.04

-11.35

PLNDPSNPVS

16.35

-6.07

-9.38

PPPPPPKPPL

16.86

-8.53

-11.84

P40343

QPSPQPQPIH

13.87

-6.19

-9.50

APSDPPYPKE

14.12

-7.31

-10.62

PSPQPQPIHS

15.63

-5.32

-8.63

P53238

RPIPPAPTHY

12.51

-8.36

-11.67

IPPAPTHYNN

12.91

-8.37

-11.68

GRPIPPAPTH

13.97

-6.56

-9.87

P04051

DRSLPHFPKN

11.58

-7.76

-11.07

RSLPHFPKNS

14.14

-6.08

-9.39

SLPHFPKNSK

14.59

-7.63

-10.94

P48524

KRKPLLRPQR

11.07

-9.75

-13.06

PLLRPQRSDF

11.87

-10.59

-13.90

FPPKRKPLLR

12.05

-9.64

-12.95

P40453

KRPPPPPPVS

10.59

-7.91

-11.22

RPPPPPPVSM

13.12

-8.77

-12.08

PDLPIRLRKR

13.52

-8.99

-12.30

P38753

TPVMPPQRQS

11.87

-8.00

-11.31

LPIQHPTNSA

14.99

-6.47

-9.78

SNLPIQHPTN

15.58

-4.48

-7.79

P38351

PQLPPKLLVY

15.31

-9.48

-12.79

VPQLPPKLLV

15.38

-8.07

-11.38

VYPESPETNA

17.03

-3.50

-6.81

Q06524

WKYNPTVPNE

15.46

-6.95

-10.26

YNPTVPNELL

17.38

-7.21

-10.52

P40020

PPLTPEKNLY

11.84

-7.66

-10.97

VLPPLPFPLY

12.85

-7.23

-10.54

PLPFPLYDEK

13.21

-8.59

-11.90

P36041

FPMHPNFPNG

9.45

-10.41

-13.72

TDLRPVIPRG

10.58

-9.69

-13.00

QQPQPPYPNM

11.39

-8.31

-11.62

Q03935

PPLPNLMHLS

12.95

-7.11

-10.42

MHQSPIHPSY

13.19

-4.96

-8.27

YQINPPLPNG

14.12

-9.23

-12.54

Q03497

PKVKPSKPEA

11.79

-6.82

-10.13

QHKPKVKPSK

12.25

-5.60

-8.91

RPAPKPPSSA

12.87

-6.82

-10.13

P40041

IPLSPPSSSN

17.54

-5.77

-9.08

KIPLSPPSSS

17.65

-5.50

-8.81

P10566

TRPIPAIPMD

14.56

-7.42

-10.73

RPIPAIPMDL

17.60

-6.09

-9.40

Q04439

KPKEPMFEAA

10.04

-9.27

-12.58

PPPPSSKPKE

13.22

-7.58

-10.89

APPPPGMQNK

13.44

-10.26

-13.57

O13527

PRGIPGYALH

11.03

-8.54

-11.85

PLNPKGKKLR

12.61

-5.90

-9.21

NVPLNPKGKK

13.37

-4.52

-7.83

P53901

MRPIPPLPTE

12.10

-9.01

-12.32

RPIPPLPTES

12.77

-7.81

-11.12

LPPIPTRDDM

13.47

-8.42

-11.73

Q12446

FPFPVPQQQF

10.94

-8.65

-11.96

PPPPHRHVTS

11.35

-5.72

-9.03

PPPPPAFLTQ

12.77

-9.72

-13.03

 


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