ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-18.PDB
Scoring matrix: HSE1_1SEM-18_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 15.54
Foldx random average score for Saccharomyces cerevisiae: 15.718

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1687804
Proteins after disorder filtering: 4582
 Total fragments: 105566
Proteins after pattern filtering: 2102
 Total fragments: 10538
Proteins after MINT filtering: 27
 Total fragments: 286


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

15.54

2.61

0.00

Best peptides

RFFIKSIWYY

0.00

2.02

-0.59

         
Interactors      
Q06604

YSNIPSSKPA

9.22

-3.57

-6.18

KPLLPTRPNK

10.99

-3.73

-6.34

KPTPPSPPAK

11.18

-1.81

-4.42

Q06108

QPATPGSTRS

8.83

0.11

-2.50

LMNLPGVSPS

10.44

-3.12

-5.73

KTDPRSPYYI

10.73

0.62

-1.99

P40073

GYPQQQPSHT

13.51

1.18

-1.43

FDGYPQQQPS

15.23

-1.10

-3.71

P25604

LPPKPKSPHL

10.21

-1.83

-4.44

TPPLPPKPKS

13.71

-1.99

-4.60

PPPQPASNAL

13.74

-2.56

-5.17

P40325

LYVQPGDPRL

10.15

-1.00

-3.61

HQSRPHQRPS

11.56

-4.21

-6.82

LPWTYPPRFY

12.02

-3.40

-6.01

Q06412

SPKSPRDSSK

10.98

0.82

-1.79

PMVSPSSQSR

11.73

0.98

-1.63

PPPPLSTSRN

12.19

-1.61

-4.22

Q66RC5

SPLIPDNPGR

13.10

-2.05

-4.66

SNPSPLIPDN

15.62

1.82

-0.79

P36037

KPPLKLPINV

9.40

-3.20

-5.81

P40341

KPPLNDPSNP

11.90

-1.98

-4.59

LNDPSNPVSK

14.79

1.95

-0.66

PPPPKPPLND

15.35

-2.03

-4.64

P40343

QPQQPSPQPQ

13.11

-2.01

-4.62

VELAPSDPPY

13.24

0.15

-2.46

PSPQPQPIHS

13.72

0.51

-2.10

P53238

RPIPPAPTHY

10.58

-0.10

-2.71

IPPAPTHYNN

13.27

-0.41

-3.02

P04051

LPHFPKNSKT

10.33

-0.58

-3.19

PAMLPGSSNG

10.84

-3.12

-5.73

RSLPHFPKNS

12.64

-0.95

-3.56

P48524

RKPLLRPQRS

8.34

-3.74

-6.35

KPLLRPQRSD

13.15

-4.01

-6.62

KRKPLLRPQR

13.51

-0.43

-3.04

P40453

DCPRCGPTAS

11.78

-1.16

-3.77

PPDLPIRLRK

12.21

-4.52

-7.13

WKPPDLPIRL

12.95

2.63

0.02

P38753

YSPYPSNLPI

11.10

-2.32

-4.93

NLPIQHPTNS

12.79

-0.93

-3.54

PYPSNLPIQH

13.40

2.40

-0.21

P38351

LPVPQLPPKL

13.69

-0.20

-2.81

PQLPPKLLVY

14.92

0.02

-2.59

VYPESPETNA

15.67

0.06

-2.55

P40020

LPPLPFPLYD

8.07

-3.63

-6.24

LPPYLSPQNK

10.13

-1.47

-4.08

YLTPESPLNR

12.86

-1.00

-3.61

P36041

PMPIPSIINA

8.62

-0.96

-3.57

RPVIPRGPSS

10.66

-1.06

-3.67

MPPPPGLVQF

11.26

-0.62

-3.23

Q03935

QPPLPNLMHL

9.55

-2.49

-5.10

RSMHQSPIHP

11.26

-0.45

-3.06

HQSPIHPSYI

12.04

1.63

-0.98

Q03497

KPSKPEAKSK

10.79

-1.56

-4.17

KKSFPSKNPL

10.91

-1.25

-3.86

LPPIPPTKSK

11.20

-1.92

-4.53

P40041

PLSPPSSSNM

13.73

0.50

-2.11

IPLSPPSSSN

15.32

0.31

-2.30

KIPLSPPSSS

15.32

-0.64

-3.25

Q03973

NGPTHAPVPI

15.42

-0.99

-3.60

P10566

IPAIPMDLPD

11.17

-2.85

-5.46

TRPIPAIPMD

12.95

-0.68

-3.29

Q04439

APPPPGMQNK

11.50

-1.12

-3.73

PPPPPSSKPK

11.71

-1.71

-4.32

KPKEPMFEAA

12.73

-1.34

-3.95

O13527

FYGHPSMIPY

9.75

-2.61

-5.22

HSPQNGPYPQ

10.73

-3.69

-6.30

FPQYPSSVGT

11.09

-2.48

-5.09

P53901

LPPLPTTSNS

11.52

-4.49

-7.10

IPPLPTESEY

12.06

-0.54

-3.15

LPPIPTRDDM

12.81

-0.23

-2.84

Q12446

IPEIPSTQSA

10.13

-0.34

-2.95

LPQLPNRNNR

10.53

-4.37

-6.98

PPTLPSTTSA

11.78

-1.09

-3.70

 


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