ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1SEM-14.PDB
Scoring matrix: HSE1_1SEM-14_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.6
Foldx random average score for Saccharomyces cerevisiae: 16.751

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1359810
Proteins after disorder filtering: 4274
 Total fragments: 51671
Proteins after pattern filtering: 1742
 Total fragments: 5739
Proteins after MINT filtering: 28
 Total fragments: 192


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.60

-1.72

0.00

Best peptides

WWFRIHKKR

0.00

-5.54

-3.82

         
Interactors      
Q06604

GPRMPSRGR

10.06

-7.16

-5.44

EKGPRMPSR

10.77

-6.16

-4.44

TPPSPPAKR

11.02

-4.97

-3.25

Q06108

TDPPPQPRR

12.38

-2.90

-1.18

QPATPGSTR

13.35

-5.51

-3.79

TDPRSPYYI

14.02

-3.79

-2.07

P40073

YPQQQPSHT

14.52

-4.06

-2.34

P25604

LPPKPNTQL

14.51

-5.78

-4.06

PKPKSPHLK

15.07

-5.03

-3.31

TPPLPPKPK

15.45

-6.70

-4.98

P40325

SLPWTYPPR

10.78

-4.60

-2.88

RPHQRPSTM

13.19

-7.42

-5.70

QSQPPRPPR

13.38

-6.36

-4.64

Q06412

PPPPLSTSR

11.35

-7.18

-5.46

PKLPPLNTR

12.43

-5.87

-4.15

SPNSPKSPR

12.70

-3.42

-1.70

Q66RC5

PLIPDNPGR

11.66

-6.31

-4.59

P36037

KPPLKLPIN

12.54

-7.04

-5.32

PPLKLPINV

15.77

-4.98

-3.26

P40341

KPPLNDPSN

14.69

-4.99

-3.27

PPPPKPPLN

16.72

-4.79

-3.07

P40343

PQPQPIHSV

15.55

-2.73

-1.01

P53238

PAGRPIPPA

15.17

-6.78

-5.06

PPAPTHYNN

15.96

-4.80

-3.08

P04051

PHFPKNSKT

13.72

-3.38

-1.66

DRSLPHFPK

14.54

-6.70

-4.98

RSLPHFPKN

14.68

-4.44

-2.72

P48524

PPKRKPLLR

6.57

-9.31

-7.59

RKPLLRPQR

7.53

-10.31

-8.59

KPLLRPQRS

13.95

-6.71

-4.99

P40453

PPDLPIRLR

8.35

-8.28

-6.56

WKPPDLPIR

10.78

-6.72

-5.00

PDLPIRLRK

14.14

-4.95

-3.23

P38753

NTPVMPPQR

10.51

-6.58

-4.86

NLPIQHPTN

14.27

-6.81

-5.09

YPSNLPIQH

14.60

-5.79

-4.07

P38351

LPVPQLPPK

15.99

-4.90

-3.18

VPQLPPKLL

16.29

-6.29

-4.57

PQLPPKLLV

16.64

-2.72

-1.00

Q06524

NPTVPNELL

14.87

-4.87

-3.15

P40020

LPPLPFPLY

12.57

-7.61

-5.89

PPPLTPEKN

13.71

-6.98

-5.26

LTPESPLNR

14.02

-5.84

-4.12

P36041

TDLRPVIPR

8.90

-6.57

-4.85

GVPPNFPQR

10.71

-6.22

-4.50

HPNFPNGPM

12.53

-6.29

-4.57

Q04439

NIPTPPQNR

12.37

-4.30

-2.58

PSSKPKEPM

14.34

-5.82

-4.10

PSPPTAATR

14.84

-4.18

-2.46

Q03497

HKPKVKPSK

13.94

-4.12

-2.40

SFPSKNPLK

14.19

-2.87

-1.15

PIPPTKSKT

14.73

-4.70

-2.98

P40041

KIPLSPPSS

15.74

-4.82

-3.10

Q03973

ENGPTHAPV

15.95

-4.37

-2.65

P10566

TRPIPAIPM

15.11

-4.67

-2.95

AIPMDLPDY

15.84

-4.52

-2.80

Q03935

QPPLPNLMH

12.33

-8.68

-6.96

IQPPLPNLM

15.20

-4.41

-2.69

HQSPIHPSY

16.06

-2.31

-0.59

O13527

MIPYTPYQM

12.86

-5.44

-3.72

VPLNPKGKK

13.90

-4.58

-2.86

IHPRGIPGY

14.16

-4.82

-3.10

P53901

NDPIILPPT

12.40

-3.93

-2.21

PPLPPIPTR

12.85

-5.34

-3.62

PPIPTRDDM

15.44

-8.39

-6.67

Q12446

RPLPQLPNR

10.70

-4.81

-3.09

PPPPPRASR

11.10

-9.80

-8.08

LPPASPEVR

12.83

-5.23

-3.51

 


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