ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1OEB-29.PDB
Scoring matrix: HSE1_1OEB-29_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.95
Foldx random average score for Saccharomyces cerevisiae: 14.575

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1368628
Proteins after disorder filtering: 4035
 Total fragments: 49299
Proteins after pattern filtering: 2030
 Total fragments: 11930
Proteins after MINT filtering: 27
 Total fragments: 451


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.95

-2.29

0.00

Best peptides

DYPPRRKRRK

0.00

-9.34

-7.05

         
Interactors      
Q06604

SPPPLPTRRD

4.77

-13.67

-11.38

EKPLLPTRPN

5.29

-12.80

-10.51

KGPRMPSRGR

8.63

-12.44

-10.15

Q06108

DPPPQPRRLS

7.53

-12.57

-10.28

TDPPPQPRRL

8.77

-9.37

-7.08

INMPIPKKLP

9.65

-11.23

-8.94

P40073

GYPQQQPSHT

11.93

-8.72

-6.43

QFDGYPQQQP

13.55

-6.34

-4.05

P25604

NTPPLPPKPK

7.11

-11.67

-9.38

QAPSLPPKPN

8.57

-12.09

-9.80

PLPPKPKSPH

9.54

-10.79

-8.50

P40325

SQPPRPPRPA

4.68

-12.42

-10.13

LPWTYPPRFY

6.47

-11.42

-9.13

SQPRPPPRPQ

7.49

-10.82

-8.53

Q06412

PNSPKSPRDS

9.71

-7.75

-5.46

EFFTKPPPPL

10.65

-9.19

-6.90

PPPPLSTSRN

11.13

-8.22

-5.93

Q66RC5

LIPDNPGRLL

9.12

-10.74

-8.45

PLIPDNPGRL

11.58

-6.33

-4.04

PSPLIPDNPG

11.98

-9.91

-7.62

P36037

GKPPLKLPIN

10.81

-9.58

-7.29

KPPLKLPINV

11.50

-9.68

-7.39

PPLKLPINVS

12.76

-10.03

-7.74

P40341

PPPPPPPKPP

10.80

-10.59

-8.30

PPPPKPPLND

11.17

-11.70

-9.41

PKPPLNDPSN

12.28

-8.13

-5.84

P40343

LAPSDPPYPK

11.52

-8.81

-6.52

PSPQPQPIHS

13.20

-7.43

-5.14

SPQPQPIHSV

13.32

-7.85

-5.56

P53238

QKPAGRPIPP

11.36

-8.19

-5.90

PIPPAPTHYN

12.06

-9.60

-7.31

AGRPIPPAPT

12.82

-8.02

-5.73

P04051

RSLPHFPKNS

10.68

-8.56

-6.27

QDRSLPHFPK

11.03

-7.71

-5.42

SLPHFPKNSK

11.31

-9.34

-7.05

P48524

RKPLLRPQRS

6.93

-9.93

-7.64

KPLLRPQRSD

8.15

-11.75

-9.46

PKRKPLLRPQ

9.37

-9.27

-6.98

P40453

PDLPIRLRKR

5.52

-10.34

-8.05

KPPDLPIRLR

6.81

-15.84

-13.55

WKPPDLPIRL

8.61

-11.81

-9.52

Q06697

GSSGGPRKDP

14.54

-6.67

-4.38

P38753

NTPVMPPQRQ

9.13

-9.74

-7.45

PYPSNLPIQH

11.24

-10.30

-8.01

TPVMPPQRQS

11.87

-8.34

-6.05

P38351

PVPQLPPKLL

9.11

-12.26

-9.97

KLLVYPESPE

11.52

-8.46

-6.17

VYPESPETNA

13.34

-8.15

-5.86

Q06524

TWKYNPTVPN

13.06

-8.05

-5.76

YNPTVPNELL

13.63

-9.17

-6.88

P40020

KSRVLPPLPF

10.29

-10.63

-8.34

VLPPLPFPLY

10.39

-11.76

-9.47

PYLSPQNKDK

10.76

-7.83

-5.54

P36041

VPPNFPQRMM

7.00

-12.39

-10.10

PQPPYPNMML

8.67

-11.51

-9.22

DLRPVIPRGP

8.73

-10.63

-8.34

Q04439

PPPPPSSKPK

11.08

-8.72

-6.43

SSKPKEPMFE

11.73

-8.98

-6.69

QSNARPSPPT

12.44

-9.43

-7.14

Q03497

NGKFIPSRPA

8.75

-10.95

-8.66

SFPSKNPLKN

9.16

-10.54

-8.25

PLPPIPPTKS

9.67

-10.69

-8.40

P10566

STRPIPAIPM

10.32

-8.90

-6.61

RPIPAIPMDL

13.42

-6.91

-4.62

PIPAIPMDLP

13.44

-8.34

-6.05

Q03935

IQPPLPNLMH

8.05

-13.21

-10.92

PYQINPPLPN

10.63

-10.06

-7.77

SNPIQPPLPN

10.70

-10.17

-7.88

O13527

LNVPLNPKGK

10.41

-8.84

-6.55

PLNPKGKKLR

11.24

-8.77

-6.48

SFYGHPSMIP

11.50

-9.05

-6.76

P53901

PLPPIPTRDD

5.88

-11.39

-9.10

NQPPLPPIPT

8.42

-11.21

-8.92

AMRPIPPLPT

9.19

-11.09

-8.80

Q12446

PLPQLPNRNN

6.68

-12.14

-9.85

PAPPPPPRRG

7.19

-13.89

-11.60

APPPPPHRHV

7.66

-10.25

-7.96

 


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