ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: HSE1_1GCQ-21.PDB
Scoring matrix: HSE1_1GCQ-21_mat
Uniprot code: P38753
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 18.06
Foldx random average score for Saccharomyces cerevisiae: 16.965

Available information for P38753 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 49
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1901612
Proteins after disorder filtering: 4460
 Total fragments: 79696
Proteins after pattern filtering: 1741
 Total fragments: 4656
Proteins after MINT filtering: 26
 Total fragments: 136


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

18.06

0.45

0.00

Best peptides

EWKMGRPTMR

0.00

-1.49

-1.94

         
Interactors      
Q06604

PLLPTRPNKA

9.58

-4.21

-4.66

EKGPRMPSRG

12.32

-5.89

-6.34

RVKPAPPVSR

13.15

-3.56

-4.00

Q06108

DPPPQPRRLS

14.09

-4.09

-4.54

LPGVSPSCLA

14.63

-3.74

-4.19

CKSPYSPYTG

14.76

-1.91

-2.36

P40073

GYPQQQPSHT

14.59

-2.14

-2.59

P25604

PPKPKSPHLK

9.13

-3.93

-4.38

SLPPKPNTQL

13.82

-2.82

-3.26

PPQPASNALD

15.29

-2.52

-2.96

P40325

YVQPGDPRLG

10.81

-3.34

-3.78

LPWTYPPRFY

13.60

-3.90

-4.34

SRPHQRPSTM

13.81

-3.16

-3.61

Q06412

PKSPRDSSKQ

14.69

-1.95

-2.40

PPPPLSTSRN

14.95

-4.09

-4.54

PNSPKSPRDS

15.58

-2.07

-2.51

Q66RC5

PLIPDNPGRL

13.28

-4.90

-5.35

LIPDNPGRLL

14.05

-2.98

-3.42

P36037

KPPLKLPINV

15.60

-1.95

-2.40

PPLKLPINVS

15.87

-3.57

-4.01

P40341

LNDPSNPVSK

13.90

-3.63

-4.08

P40343

SPQPQPIHSV

15.83

-1.12

-1.57

P53238

PIPPAPTHYN

12.18

-3.55

-3.99

P04051

RSLPHFPKNS

14.05

-3.13

-3.57

SLPHFPKNSK

15.30

-4.82

-5.27

NPAMLPGSSN

16.64

-1.96

-2.40

P48524

RKPLLRPQRS

12.00

-6.48

-6.93

FPPKRKPLLR

14.07

-4.67

-5.12

KPLLRPQRSD

16.87

-1.63

-2.07

P40453

PDLPIRLRKR

11.06

-4.63

-5.08

WKPPDLPIRL

13.29

-5.43

-5.88

TKVPEPPSWK

13.85

-2.51

-2.95

P38753

NLPIQHPTNS

10.07

-4.06

-4.50

LPIQHPTNSA

14.77

-3.81

-4.25

NTPVMPPQRQ

16.11

-4.95

-5.40

P38351

VYPESPETNA

14.44

-1.30

-1.75

PVPQLPPKLL

15.07

-5.01

-5.46

LVYPESPETN

16.43

0.20

-0.25

Q06524

KYNPTVPNEL

14.07

-1.44

-1.89

P40020

SEEPTSPTRQ

10.61

-5.22

-5.67

MSLPVTPVKS

13.63

-2.70

-3.15

PPYLSPQNKD

13.84

-4.08

-4.53

P36041

HQGPQFPVMG

11.50

-4.48

-4.93

SPMPIPSIIN

14.60

-3.57

-4.01

VPPNFPQRMM

14.68

-4.41

-4.86

Q03935

PPLPNLMHLS

11.74

-4.23

-4.68

PLPNGLPNQS

13.01

-4.30

-4.75

HQSPIHPSYI

14.80

-1.59

-2.04

Q03497

PLPPIPPTKS

11.37

-3.74

-4.19

THAPTTPNRT

13.14

-5.18

-5.63

TGLPGSPQVS

14.64

-1.40

-1.85

P40041

KIPLSPPSSS

15.64

-2.73

-3.17

Q04439

PPPPGMQNKA

12.49

-4.28

-4.73

NNIPTPPQNR

12.94

-1.97

-2.42

NARPSPPTAA

13.98

-2.74

-3.19

O13527

PLNPKGKKLR

10.05

-3.39

-3.84

DLPPESPTEF

13.05

-2.27

-2.71

SAVPENPHHA

13.22

-2.41

-2.86

P53901

DPIILPPTFS

10.69

-4.92

-5.37

KLPPLPTTSN

13.03

-3.51

-3.95

PPIPTRDDMS

14.07

-1.79

-2.23

Q12446

RPLPQLPNRN

10.21

-6.34

-6.79

PPPPMRTTTE

13.08

-1.54

-1.99

PPPPTAETFD

13.62

-2.62

-3.06

 


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