ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-9.PDB
Scoring matrix: FUS1_1SHF-9_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.26
Foldx random average score for Saccharomyces cerevisiae: 13.342

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1361453
Proteins after disorder filtering: 4444
 Total fragments: 50459
Proteins after pattern filtering: 1964
 Total fragments: 8600
Proteins after MINT filtering: 20
 Total fragments: 121


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.26

0.75

0.00

Best peptides

RRYWIPRH

0.00

-4.43

-5.18

         
Interactors      
P11710

SKPLPLTP

10.25

-3.70

-4.45

Q12280

TPPLRPQS

10.67

-3.07

-3.82

INTAPASP

10.98

-1.66

-2.41

NVTPPLRP

12.74

-3.42

-4.17

P36119

RPTVQPSN

10.40

-2.12

-2.87

TRPTVQPS

12.59

-1.67

-2.42

P24583

RANAPLPP

10.37

-1.29

-2.04

LPPQPRKH

10.69

-4.19

-4.94

NAPLPPQP

11.18

-2.83

-3.58

P39732

RHPSIAPP

8.51

-2.18

-2.93

RSPSVSPV

11.08

-1.43

-2.18

P21268

SKPISPPP

11.51

-2.93

-3.68

KPISPPPS

11.55

-3.25

-4.00

NLSKPISP

12.74

-3.28

-4.03

P53950

PNGAPLRR

11.93

-2.06

-2.81

PAPLLPLP

11.94

-2.94

-3.69

TPPAPLLP

12.22

-2.61

-3.36

P40450

PKLFPRLS

9.60

-4.06

-4.81

PPPLPDLF

10.37

-5.08

-5.83

KLPQLPPP

11.02

-3.17

-3.92

P32917

RFPPYSPL

9.31

-2.26

-3.01

IPPKVAPF

9.63

-1.88

-2.63

SPLLPPFG

10.80

-3.43

-4.18

P25376

RPSSQPHL

10.73

-0.47

-1.22

P40020

SRVLPPLP

8.76

-4.86

-5.61

RVLPPLPF

9.35

-4.09

-4.84

RPPPLTPE

10.87

-3.10

-3.85

P41832

IPPAPPMM

9.58

-3.95

-4.70

APPMMPAS

10.39

-4.48

-5.23

PPPVPAKL

10.94

-4.53

-5.28

P16892

GEPIPPSF

12.33

-3.18

-3.93

Q03466

VPMAPDTF

13.32

-2.07

-2.82

P53046

QLSTPPTP

12.75

-3.40

-4.15

TPPTPKSA

13.18

-2.23

-2.98

P14681

EPEYPPLN

11.46

-5.07

-5.82

P31374

RKTKPPPP

6.05

-4.25

-5.00

KPGTPVFP

9.89

-3.19

-3.94

SPERPSFR

10.48

-4.80

-5.55

P53947

FNPIQDPF

12.33

-1.40

-2.15

SPFNPIQD

12.85

-2.18

-2.93

Q12753

RYPPMAPT

9.29

-3.82

-4.57

MIKPKGRP

9.47

-5.50

-6.25

IPQSPPLS

10.25

-3.30

-4.05

P34250

KPAYVPPE

10.68

-3.44

-4.19

KPSNPPSS

11.62

-1.67

-2.42

PKEPPARK

11.82

-2.81

-3.56

 


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