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Matrix information:
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ADAN-name: FUS1_1SHF-8.PDB
Scoring matrix: FUS1_1SHF-8_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.55
Foldx random average score for Saccharomyces cerevisiae: 11.567 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1287260
Proteins after disorder filtering: 4202
Total fragments: 48980
Proteins after pattern filtering: 2023
Total fragments: 9652
Proteins after MINT filtering: 23
Total fragments: 168
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
15.55
|
1.10 |
0.00 |
| Best peptides |
HRRPWPPR |
0.00
|
-2.23 |
-3.33 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPN |
9.90
|
-2.30 |
-3.40 |
|
SKPLPLTP |
11.35
|
-2.16 |
-3.26 |
| P36119 |
TRPTVQPS |
9.14
|
-2.13 |
-3.23 |
|
TTRPTVQP |
10.29
|
-3.10 |
-4.20 |
| P40073 |
YPQQQPSH |
10.59
|
-3.24 |
-4.34 |
| P24583 |
ANAPLPPQ |
7.61
|
-3.95 |
-5.05 |
|
PLPPQPRK |
9.35
|
-4.56 |
-5.66 |
|
APLPPQPR |
10.65
|
-0.94 |
-2.04 |
| P53947 |
PFNPIQDP |
10.15
|
-3.68 |
-4.78 |
|
FNPIQDPF |
11.34
|
-1.76 |
-2.86 |
|
ASPFNPIQ |
11.53
|
-1.19 |
-2.29 |
| Q03466 |
PMAPDTFN |
11.15
|
-2.42 |
-3.52 |
| P34250 |
YPKEPPAR |
8.39
|
-3.15 |
-4.25 |
|
SNPDLPTA |
9.52
|
-3.71 |
-4.81 |
|
PKPAYVPP |
9.60
|
-2.66 |
-3.76 |
| Q12280 |
VTPPLRPQ |
8.34
|
-3.09 |
-4.19 |
|
GSPSKPGN |
11.15
|
-1.95 |
-3.05 |
|
PLRPQSSS |
11.44
|
-2.28 |
-3.38 |
| P39732 |
TRHPSIAP |
8.24
|
-3.46 |
-4.56 |
|
SRSPSVSP |
9.00
|
-3.11 |
-4.21 |
|
SPSVSPVR |
10.89
|
-1.64 |
-2.74 |
| P40091 |
QNPSHPHH |
10.57
|
-2.43 |
-3.53 |
|
SQNPSHPH |
11.15
|
-0.43 |
-1.53 |
| P40450 |
SPKLFPRL |
6.88
|
-3.14 |
-4.24 |
|
APPPLPDL |
6.94
|
-4.24 |
-5.34 |
|
KLPQLPPP |
8.19
|
-5.97 |
-7.07 |
| P25376 |
DRPSSQPH |
8.64
|
-0.44 |
-1.54 |
|
RPSSQPHL |
10.29
|
-2.50 |
-3.60 |
| P41832 |
PPPPLPSV |
8.06
|
-4.19 |
-5.29 |
|
VIPPAPPM |
8.11
|
-3.79 |
-4.89 |
|
PPPPVPAK |
9.04
|
-3.62 |
-4.72 |
| P31374 |
TPDDLPPL |
7.96
|
-3.10 |
-4.20 |
|
EQPRLPST |
8.64
|
-4.12 |
-5.22 |
|
KKPGTPVF |
8.72
|
-2.98 |
-4.08 |
| P32917 |
YSPLLPPF |
7.58
|
-4.44 |
-5.54 |
|
SRFPPYSP |
7.98
|
-1.57 |
-2.67 |
|
NIPPKVAP |
9.18
|
-3.52 |
-4.62 |
| P40020 |
VLPPLPFP |
8.07
|
-6.33 |
-7.43 |
|
DRPPPLTP |
8.15
|
-2.85 |
-3.95 |
|
SRVLPPLP |
8.31
|
-2.44 |
-3.54 |
| P16892 |
GEPIPPSF |
10.63
|
-2.75 |
-3.85 |
|
EGEPIPPS |
11.37
|
-1.61 |
-2.71 |
| P40210 |
VDPTEPQT |
11.52
|
-1.71 |
-2.81 |
| Q12114 |
EPVGTPNI |
10.36
|
-1.50 |
-2.60 |
| P21268 |
PISPPPSL |
9.56
|
-2.03 |
-3.13 |
|
SKPISPPP |
9.92
|
-3.26 |
-4.36 |
|
LSKPISPP |
10.86
|
-1.45 |
-2.55 |
| P53950 |
PLLPLPSL |
6.93
|
-6.09 |
-7.19 |
|
PPAPLLPL |
8.06
|
-2.96 |
-4.06 |
|
PAPLLPLP |
9.58
|
-3.86 |
-4.96 |
| Q12753 |
HRYPPMAP |
7.34
|
-3.86 |
-4.96 |
|
PRMPKTGS |
8.20
|
-3.01 |
-4.11 |
|
SIPQSPPL |
8.83
|
-3.33 |
-4.43 |
| P14681 |
DEPEYPPL |
9.36
|
-2.56 |
-3.66 |
|
DPSDEPEY |
10.81
|
-1.72 |
-2.82 |
|
PEYPPLNL |
11.22
|
-2.01 |
-3.11 |
|
