ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-4.PDB
Scoring matrix: FUS1_1SHF-4_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.59
Foldx random average score for Saccharomyces cerevisiae: 17.691

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1294340
Proteins after disorder filtering: 4317
 Total fragments: 63244
Proteins after pattern filtering: 2164
 Total fragments: 13816
Proteins after MINT filtering: 23
 Total fragments: 190


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.59

-1.06

0.00

Best peptides

RHPFRWRRRH

0.00

-0.35

0.71

         
Interactors      
P11710

PLPLTPNSKY

15.59

-5.04

-3.98

SKPLPLTPNS

17.30

-3.25

-2.19

P36119

TRPTVQPSNQ

14.32

-3.84

-2.78

SSTTRPTVQP

15.39

-3.60

-2.54

P40073

QFDGYPQQQP

14.03

-4.96

-3.90

GYPQQQPSHT

17.06

-4.88

-3.82

P24583

ANAPLPPQPR

12.89

-6.37

-5.31

RANAPLPPQP

13.19

-7.76

-6.70

ERANAPLPPQ

14.77

-4.80

-3.74

P53947

ASPFNPIQDP

14.64

-5.59

-4.53

FNPIQDPFTD

17.26

-2.65

-1.59

PFNPIQDPFT

17.54

-4.93

-3.87

P34250

LYPKEPPARK

9.31

-6.03

-4.97

YHSKKPSNPP

13.10

-5.32

-4.26

LSEPKPAYVP

13.51

-4.29

-3.23

P53046

QLSTPPTPKS

14.67

-4.41

-3.35

NQLSTPPTPK

14.78

-3.17

-2.11

STPPTPKSAG

14.95

-3.21

-2.15

Q12280

VTPPLRPQSS

12.93

-2.49

-1.43

GTNVTPPLRP

13.08

-7.40

-6.34

NVTPPLRPQS

14.23

-6.74

-5.68

P39732

RHPSIAPPSK

11.85

-5.65

-4.59

RSPSVSPVRT

13.55

-3.24

-2.18

NSTRHPSIAP

16.02

-3.63

-2.57

P40091

QNPSHPHHNS

13.76

-5.27

-4.21

PSHPHHNSRP

14.62

-5.91

-4.85

SSPASSPVTW

17.11

-2.86

-1.80

P40450

QLPPPPPPPP

11.48

-6.31

-5.25

KLPQLPPPPP

11.96

-6.44

-5.38

VTPPAPPLPN

12.33

-3.05

-1.99

P25376

GSNDRPSSQP

15.85

-4.09

-3.03

DRPSSQPHLG

16.10

-3.28

-2.22

P41832

LSSQPPPPPP

10.76

-5.81

-4.75

ETPPPPPLPS

12.89

-3.85

-2.79

VIPPAPPMMP

12.97

-5.98

-4.92

Q03466

GSSVPMAPDT

16.14

-4.58

-3.52

SSVPMAPDTF

16.85

-3.87

-2.81

P31374

FRKTKPPPPL

10.43

-6.83

-5.77

KTKPPPPLDF

11.48

-5.43

-4.37

ISPERPSFRQ

12.14

-5.15

-4.09

P32917

QSRFPPYSPL

12.65

-3.81

-2.75

DYLPQHPHRT

13.09

-4.18

-3.12

YSPLLPPFGL

13.51

-4.65

-3.59

P40020

ISLPPYLSPQ

10.77

-4.20

-3.14

KSRVLPPLPF

11.02

-5.65

-4.59

RVLPPLPFPL

12.67

-7.85

-6.79

P16892

QTYHDPNDEP

15.56

-3.17

-2.11

Q12114

GHETAPVSPV

16.60

-4.32

-3.26

P21268

LNLSKPISPP

11.42

-6.13

-5.07

LSKPISPPPS

14.44

-3.21

-2.15

SKPISPPPSL

15.13

-3.71

-2.65

P53950

SNPNGAPLRR

14.96

-6.77

-5.71

NTPPAPLLPL

14.98

-2.33

-1.27

IFDSNPNGAP

15.10

-5.86

-4.80

Q12753

QSINSPRMPK

10.39

-5.37

-4.31

LMMIKPKGRP

10.55

-6.57

-5.51

INSPRMPKTG

10.56

-6.17

-5.11

P14681

YHDPSDEPEY

16.14

-3.63

-2.57

 


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