ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-29.PDB
Scoring matrix: FUS1_1SHF-29_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.22
Foldx random average score for Saccharomyces cerevisiae: 13.948

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1340313
Proteins after disorder filtering: 4130
 Total fragments: 54746
Proteins after pattern filtering: 2015
 Total fragments: 10545
Proteins after MINT filtering: 22
 Total fragments: 131


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.22

1.28

0.00

Best peptides

KRRPWMRRRH

0.00

-5.32

-6.60

         
Interactors      
P11710

PLPLTPNSKY

10.47

-6.03

-7.31

KPLPLTPNSK

13.27

-6.04

-7.32

PLTPNSKYNG

13.28

-4.65

-5.93

P36119

TRPTVQPSNQ

12.77

-3.04

-4.32

RPTVQPSNQS

13.25

-3.97

-5.25

P40073

QFDGYPQQQP

12.28

-4.33

-5.61

GYPQQQPSHT

13.05

-3.37

-4.65

P24583

PLPPQPRKHD

9.27

-6.06

-7.34

APLPPQPRKH

10.55

-3.84

-5.12

PPQPRKHDKT

12.95

-4.09

-5.37

P53947

PFNPIQDPFT

12.27

-4.97

-6.25

P34250

LYPKEPPARK

9.85

-6.04

-7.32

YPKEPPARKS

9.96

-6.06

-7.34

SKKPSNPPSS

10.98

-3.53

-4.81

P53046

NQLSTPPTPK

12.51

-6.59

-7.87

QLSTPPTPKS

13.83

-4.11

-5.39

Q12280

AYSGSPSKPG

9.44

-5.16

-6.44

PLRPQSSSKI

11.80

-4.20

-5.48

TNVTPPLRPQ

12.03

-5.98

-7.26

P39732

TRHPSIAPPS

9.70

-4.55

-5.83

SPSVSPVRTT

10.61

-2.40

-3.68

SRSPSVSPVR

11.96

-1.93

-3.21

P40091

SQNPSHPHHN

11.79

-4.20

-5.48

TWDPSSPSSV

13.12

-0.82

-2.10

P40450

KLPQLPPPPP

11.18

-7.66

-8.94

SVSSSPKLFP

11.18

-3.05

-4.33

APPPLPDLFK

11.40

-7.11

-8.39

P25376

DRPSSQPHLG

10.20

-6.05

-7.33

NDRPSSQPHL

12.64

-1.58

-2.86

P41832

VIPPAPPMMP

12.07

-7.33

-8.61

PPPPPMALFG

12.07

-5.59

-6.87

PKGETPPPPP

12.64

-4.30

-5.58

Q03466

SVPMAPDTFN

13.86

-2.43

-3.71

PMAPDTFNVK

13.91

-4.41

-5.69

P31374

SFRKTKPPPP

8.80

-7.77

-9.05

FRKTKPPPPL

9.00

-7.79

-9.07

KKPGTPVFPN

9.56

-7.15

-8.43

P32917

YLPQHPHRTS

9.59

-6.25

-7.53

DYLPQHPHRT

10.34

-8.62

-9.90

RFPPYSPLLP

11.22

-6.06

-7.34

P40020

EEPTSPTRQV

9.00

-4.97

-6.25

PLTPEKNLYL

10.44

-5.47

-6.75

NLYLTPESPL

10.67

-5.22

-6.50

Q12114

SLKSEPVGTP

12.05

-4.34

-5.62

P21268

SKPISPPPSL

11.42

-3.42

-4.70

PLNLSKPISP

11.76

-4.22

-5.50

PISPPPSLKK

12.79

-5.72

-7.00

P53950

NPNGAPLRRY

10.32

-5.33

-6.61

VVAPNPSIPS

12.78

-4.80

-6.08

PNGAPLRRYS

13.58

-3.97

-5.25

Q12753

MMIKPKGRPS

8.71

-9.68

-10.96

PQSINSPRMP

10.65

-4.49

-5.77

DLPDTSPMSS

10.70

-3.93

-5.21

P14681

DEPEYPPLNL

13.57

-5.40

-6.68

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER