ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-16.PDB
Scoring matrix: FUS1_1SHF-16_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.88
Foldx random average score for Saccharomyces cerevisiae: 15.827

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1543533
Proteins after disorder filtering: 4694
 Total fragments: 112339
Proteins after pattern filtering: 2281
 Total fragments: 15132
Proteins after MINT filtering: 24
 Total fragments: 212


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

17.88

5.28

0.00

Best peptides

RSPFPPIMW

0.00

10.19

4.91

         
Interactors      
P11710

LPLTPNSKY

10.36

-3.62

-8.90

PLPLTPNSK

11.48

-0.64

-5.92

SKPLPLTPN

14.20

1.18

-4.10

P36119

STTRPTVQP

10.95

1.42

-3.86

TRPTVQPSN

13.80

0.66

-4.62

PTVQPSNQS

14.38

3.26

-2.02

P40073

FDGYPQQQP

10.86

0.98

-4.30

GYPQQQPSH

14.23

3.03

-2.25

P24583

ERANAPLPP

13.48

1.51

-3.77

ANAPLPPQP

13.77

-0.28

-5.56

NAPLPPQPR

14.00

-0.04

-5.32

P53947

ASPFNPIQD

11.69

0.66

-4.62

SPFNPIQDP

15.27

-1.21

-6.49

P34250

YHSKKPSNP

8.90

0.26

-5.02

HSKKPSNPP

9.15

-0.99

-6.27

KPSNPPSSG

9.50

-1.98

-7.26

P53046

TPPTPKSAG

12.17

-0.37

-5.65

NQLSTPPTP

13.37

1.50

-3.78

QLSTPPTPK

14.35

0.99

-4.29

Q12280

TNVTPPLRP

10.25

0.05

-5.23

YSGSPSKPG

10.94

0.93

-4.35

NINTAPASP

11.59

1.60

-3.68

P39732

HPSIAPPSK

9.31

0.08

-5.20

SSRSPSVSP

10.34

2.43

-2.85

STRHPSIAP

11.04

-2.36

-7.64

P40091

SPASSPVTW

10.53

1.76

-3.52

PVTWDPSSP

10.83

-0.14

-5.42

DPSSPSSVG

12.49

1.63

-3.65

P40450

LPQLPPPPP

9.73

-2.93

-8.21

VSSSPKLFP

11.22

-0.06

-5.34

KLPQLPPPP

11.66

-2.40

-7.68

P25376

RPSSQPHLG

8.70

-1.57

-6.85

SNDRPSSQP

10.77

0.94

-4.34

PSSQPHLGY

11.95

2.40

-2.88

P41832

IPPAPPMMP

6.94

-1.38

-6.66

LSSQPPPPP

10.23

-1.19

-6.47

VIPPAPPMM

10.85

-1.39

-6.67

Q03466

SVPMAPDTF

10.53

-0.02

-5.30

SGSSVPMAP

14.25

1.51

-3.77

VPMAPDTFN

15.31

-0.79

-6.07

P31374

LSNKKPGTP

8.60

0.30

-4.98

FRKTKPPPP

9.72

-3.54

-8.82

GNNISPERP

10.04

-1.65

-6.93

P32917

YSPLLPPFG

5.84

0.81

-4.47

FPPYSPLLP

7.36

-2.22

-7.50

QSRFPPYSP

7.81

-2.67

-7.95

P40020

LPPLPFPLY

8.33

-2.62

-7.90

KSRVLPPLP

8.57

-0.55

-5.83

LPPYLSPQN

9.74

-1.36

-6.64

P16892

HDPNDEPEG

14.03

3.00

-2.28

EPEGEPIPP

14.66

-0.19

-5.47

TYHDPNDEP

15.76

0.69

-4.59

P40210

HDEVDPTEP

13.04

0.62

-4.66

VDPTEPQTN

14.85

1.95

-3.33

Q12114

GHETAPVSP

10.47

1.31

-3.97

LKSEPVGTP

12.60

-0.97

-6.25

P21268

LNLSKPISP

9.34

0.67

-4.61

LSKPISPPP

13.60

1.00

-4.28

PISPPPSLK

14.50

0.73

-4.55

P53950

PNGAPLRRY

12.68

1.47

-3.81

NTPPAPLLP

13.01

-0.85

-6.13

IGSNTPPAP

13.62

0.58

-4.70

Q12753

QSINSPRMP

7.39

-1.74

-7.02

NSPRMPKTG

8.67

-1.29

-6.57

NHRYPPMAP

8.89

-2.79

-8.07

P14681

DPSDEPEYP

12.80

-0.03

-5.31

HDPSDEPEY

14.30

1.86

-3.42

DEPEYPPLN

14.63

0.99

-4.29

 


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