ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-15.PDB
Scoring matrix: FUS1_1SHF-15_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.39
Foldx random average score for Saccharomyces cerevisiae: 13.394

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1336997
Proteins after disorder filtering: 4172
 Total fragments: 44782
Proteins after pattern filtering: 1687
 Total fragments: 5156
Proteins after MINT filtering: 19
 Total fragments: 61


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.39

2.58

0.00

Best peptides

HWFTIRRRR

0.00

0.65

-1.93

         
Interactors      
P11710

LPLTPNSKY

10.13

-3.07

-5.65

PLPLTPNSK

11.25

-2.85

-5.43

Q12280

APASPEEPK

12.50

-0.21

-2.79

P36119

RPTVQPSNQ

11.24

-2.60

-5.18

TRPTVQPSN

12.50

-0.43

-3.01

P24583

LPPQPRKHD

11.01

-5.87

-8.45

APLPPQPRK

11.57

-1.20

-3.78

NAPLPPQPR

12.01

-4.45

-7.03

P39732

RSPSVSPVR

7.90

-3.52

-6.10

HPSIAPPSK

8.03

-4.72

-7.30

RHPSIAPPS

12.57

-2.68

-5.26

P21268

KPISPPPSL

11.65

-0.49

-3.07

PISPPPSLK

11.96

-2.10

-4.68

P40091

PSHPHHNSR

12.04

-0.47

-3.05

WDPSSPSSV

13.12

1.45

-1.13

NPSHPHHNS

13.14

-2.63

-5.21

P40450

PKLFPRLSS

10.79

-2.59

-5.17

PPPLPDLFK

11.95

-2.33

-4.91

SSPKLFPRL

12.54

-2.55

-5.13

P32917

DYLPQHPHR

10.90

-1.61

-4.19

LPQHPHRTS

13.09

-3.11

-5.69

RFPPYSPLL

13.25

-1.86

-4.44

P25376

RPSSQPHLG

11.40

-0.85

-3.43

DRPSSQPHL

12.76

0.86

-1.72

P40020

RPPPLTPEK

10.26

-2.37

-4.95

LPPLPFPLY

10.37

-3.82

-6.40

LTPESPLNR

10.95

-1.75

-4.33

P41832

PPPPPVPAK

13.23

-1.96

-4.54

P53046

QLSTPPTPK

10.68

-3.49

-6.07

TPPTPKSAG

12.88

-1.13

-3.71

Q03466

SVPMAPDTF

13.13

-1.86

-4.44

P14681

HDPSDEPEY

13.31

-0.29

-2.87

P31374

NISPERPSF

10.85

-1.80

-4.38

ISPERPSFR

11.52

-1.78

-4.36

SPERPSFRQ

12.06

-3.21

-5.79

Q12753

SINSPRMPK

8.25

-2.38

-4.96

IKPKGRPST

10.10

-2.24

-4.82

PRMPKTGSR

11.38

-0.77

-3.35

P34250

LYPKEPPAR

9.50

-4.08

-6.66

YPKEPPARK

11.11

-3.00

-5.58

KKPSNPPSS

11.97

0.31

-2.27

P53950

NPNGAPLRR

12.00

-2.69

-5.27

 


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