ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-14.PDB
Scoring matrix: FUS1_1SHF-14_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 19.7
Foldx random average score for Saccharomyces cerevisiae: 14.493

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1331332
Proteins after disorder filtering: 4125
 Total fragments: 37930
Proteins after pattern filtering: 1648
 Total fragments: 4729
Proteins after MINT filtering: 18
 Total fragments: 51


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

19.70

0.89

0.00

Best peptides

FHPWYFRRK

0.00

0.83

-0.06

         
Interactors      
P11710

PLPLTPNSK

11.65

-2.29

-3.18

LPLTPNSKY

12.71

-3.02

-3.91

Q12280

APASPEEPK

14.19

0.11

-0.78

P36119

RPTVQPSNQ

11.66

-2.63

-3.52

P40073

YPQQQPSHT

12.43

-2.77

-3.66

P24583

PPQPRKHDK

11.98

-1.62

-2.51

APLPPQPRK

12.82

-4.45

-5.34

LPPQPRKHD

13.31

-1.17

-2.06

P39732

HPSIAPPSK

11.30

-3.31

-4.20

RSPSVSPVR

13.10

-3.71

-4.60

SPSVSPVRT

13.71

-3.52

-4.41

P21268

PISPPPSLK

13.54

-2.48

-3.37

P40091

WDPSSPSSV

14.35

-1.10

-1.99

P40450

PPPLPDLFK

11.74

-2.86

-3.75

SSPKLFPRL

13.56

-5.39

-6.28

PKLFPRLSS

14.35

-3.54

-4.43

P32917

YLPQHPHRT

11.86

-3.04

-3.93

LPQHPHRTS

12.63

-4.34

-5.23

IPPKVAPFG

13.13

-1.95

-2.84

P40020

LPPLPFPLY

9.62

-4.74

-5.63

LTPESPLNR

11.16

-4.95

-5.84

RPPPLTPEK

11.78

-1.52

-2.41

P41832

PPPPPVPAK

13.87

-2.99

-3.88

P53046

QLSTPPTPK

13.30

-2.45

-3.34

TPPTPKSAG

14.35

0.20

-0.69

Q03466

SVPMAPDTF

12.96

-2.03

-2.92

P31374

ISPERPSFR

11.44

-4.27

-5.16

TPDDLPPLK

13.00

-1.54

-2.43

FPNLDPTHS

13.04

-2.83

-3.72

P53947

FNPIQDPFT

11.09

-4.13

-5.02

Q12753

IKPKGRPST

10.69

-3.49

-4.38

YPPMAPTTV

10.84

-3.92

-4.81

INSPRMPKT

12.64

-3.73

-4.62

P34250

LYPKEPPAR

9.16

-5.70

-6.59

YPKEPPARK

9.64

-4.49

-5.38

KPAYVPPED

13.99

-1.49

-2.38

 


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