ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-11.PDB
Scoring matrix: FUS1_1SHF-11_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.62
Foldx random average score for Saccharomyces cerevisiae: 9.931

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1457530
Proteins after disorder filtering: 4729
 Total fragments: 88888
Proteins after pattern filtering: 2138
 Total fragments: 10009
Proteins after MINT filtering: 23
 Total fragments: 156


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.62

0.13

0.00

Best peptides

RRPRIRY

0.00

-0.71

-0.84

         
Interactors      
P11710

LPLTPNS

7.34

-3.28

-3.41

KPLPLTP

9.04

-3.08

-3.21

PLTPNSK

9.55

-2.01

-2.14

P36119

RPTVQPS

7.09

-3.90

-4.03

TRPTVQP

8.53

-1.92

-2.05

PTVQPSN

8.95

-1.95

-2.08

P40073

YPQQQPS

8.46

-2.30

-2.43

PQQQPSH

9.53

-2.52

-2.65

P24583

LPPQPRK

7.06

-3.93

-4.06

NAPLPPQ

8.85

-3.50

-3.63

PLPPQPR

9.60

-1.66

-1.79

P53947

FNPIQDP

8.83

-2.46

-2.59

PIQDPFT

9.05

-1.18

-1.31

ASPFNPI

9.26

-2.58

-2.71

P34250

KPSNPPS

6.93

-2.50

-2.63

PKEPPAR

7.69

-2.59

-2.72

KPAYVPP

7.98

-2.35

-2.48

P53046

TPPTPKS

6.63

-2.55

-2.68

Q12280

PPLRPQS

7.77

-3.93

-4.06

SPSKPGN

8.23

-1.95

-2.08

TPPLRPQ

8.86

-3.49

-3.62

P39732

RHPSIAP

7.41

-3.42

-3.55

RSPSVSP

8.59

-1.53

-1.66

PSIAPPS

9.16

-1.88

-2.01

P40091

WDPSSPS

8.21

-0.43

-0.56

NPSHPHH

9.55

-3.34

-3.47

DPSSPSS

9.72

-1.40

-1.53

P40450

PKLFPRL

7.06

-4.03

-4.16

KLPQLPP

7.70

-3.73

-3.86

SPKLFPR

8.13

-2.97

-3.10

P25376

RPSSQPH

8.65

-3.38

-3.51

PSSQPHL

9.73

-1.55

-1.68

P41832

IPPAPPM

7.30

-3.93

-4.06

PPPVPAK

7.90

-3.18

-3.31

PPMMPAS

8.13

-3.29

-3.42

Q03466

VPMAPDT

9.32

-1.61

-1.74

P31374

KPGTPVF

5.46

-3.85

-3.98

SPERPSF

6.55

-6.36

-6.49

EQPRLPS

6.65

-5.09

-5.22

P32917

FPPYSPL

6.07

-2.17

-2.30

RFPPYSP

7.04

-3.15

-3.28

YSPLLPP

7.91

-3.59

-3.72

P40020

PLPFPLY

6.08

-3.64

-3.77

RPPPLTP

7.25

-5.13

-5.26

RVLPPLP

7.44

-3.16

-3.29

P16892

GEPIPPS

7.95

-2.99

-3.12

EPIPPSF

8.66

-2.80

-2.93

Q12114

PVGTPNI

9.29

-1.86

-1.99

P21268

PISPPPS

8.45

-1.80

-1.93

KPISPPP

8.50

-2.83

-2.96

SKPISPP

8.51

-1.20

-1.33

P53950

PLLPLPS

9.13

-1.71

-1.84

PNPSIPS

9.19

-1.78

-1.91

PNGAPLR

9.34

-1.70

-1.83

Q12753

NSPRMPK

6.09

-5.26

-5.39

PKGRPST

6.64

-4.37

-4.50

YPPMAPT

7.02

-2.88

-3.01

P14681

EPEYPPL

8.35

-3.74

-3.87

PSDEPEY

8.92

-1.10

-1.23

PEYPPLN

9.91

-1.25

-1.38

 


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