ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-10.PDB
Scoring matrix: FUS1_1SHF-10_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.42
Foldx random average score for Saccharomyces cerevisiae: 12.068

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1198665
Proteins after disorder filtering: 4265
 Total fragments: 50673
Proteins after pattern filtering: 2036
 Total fragments: 10198
Proteins after MINT filtering: 21
 Total fragments: 154


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.42

-0.77

0.00

Best peptides

RRRWHRMY

0.00

-3.60

-2.83

         
Interactors      
P11710

LPLTPNSK

11.34

-4.10

-3.33

SKPLPLTP

11.50

-5.24

-4.47

PLTPNSKY

11.51

-1.71

-0.94

P36119

RPTVQPSN

9.24

-3.74

-2.97

TTRPTVQP

11.92

-0.67

0.10

P53046

LSTPPTPK

11.86

-3.19

-2.42

Q12280

TPPLRPQS

10.49

-5.70

-4.93

SPSKPGNN

10.55

-4.09

-3.32

NVTPPLRP

10.79

-4.63

-3.86

P24583

LPPQPRKH

9.22

-5.94

-5.17

RANAPLPP

10.21

-3.80

-3.03

APLPPQPR

11.29

-3.82

-3.05

P39732

RHPSIAPP

9.81

-3.58

-2.81

HPSIAPPS

11.21

-4.70

-3.93

RSPSVSPV

11.50

-1.19

-0.42

P21268

PISPPPSL

11.46

-2.65

-1.88

NLSKPISP

11.94

-2.77

-2.00

KPISPPPS

11.98

-4.36

-3.59

P40091

QNPSHPHH

10.16

-3.56

-2.79

NPSHPHHN

11.35

-4.55

-3.78

P40450

PKLFPRLS

8.07

-6.25

-5.48

APAPPPLP

8.96

-4.37

-3.60

PPPPPPLP

9.49

-4.90

-4.13

P32917

FPPYSPLL

7.82

-3.21

-2.44

RFPPYSPL

9.26

-3.12

-2.35

YLPQHPHR

10.01

-4.94

-4.17

P25376

RPSSQPHL

9.15

-3.14

-2.37

P40020

PPLPFPLY

8.26

-3.97

-3.20

SRVLPPLP

8.66

-6.30

-5.53

RVLPPLPF

8.69

-4.44

-3.67

P41832

TPPPPPLP

9.03

-4.77

-4.00

PPPPPPMA

9.58

-5.33

-4.56

PPAPPMMP

9.68

-5.60

-4.83

P16892

GEPIPPSF

11.94

-3.55

-2.78

P53947

FNPIQDPF

10.25

-3.08

-2.31

SPFNPIQD

11.19

-3.47

-2.70

ASPFNPIQ

11.66

-3.47

-2.70

Q12114

HETAPVSP

11.69

-3.15

-2.38

P31374

RKTKPPPP

6.87

-6.00

-5.23

TPVFPNLD

8.85

-5.69

-4.92

SPERPSFR

9.16

-4.79

-4.02

Q12753

MIKPKGRP

8.10

-6.74

-5.97

HRYPPMAP

8.76

-4.48

-3.71

SPRMPKTG

9.27

-5.99

-5.22

P34250

PKEPPARK

9.54

-6.33

-5.56

HSKKPSNP

9.69

-4.99

-4.22

YPKEPPAR

10.76

-4.93

-4.16

P14681

EPEYPPLN

8.65

-5.63

-4.86

P53950

TPPAPLLP

10.15

-4.55

-3.78

PNGAPLRR

10.69

-6.23

-5.46

SNTPPAPL

11.38

-2.79

-2.02

 


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