ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1SHF-1.PDB
Scoring matrix: FUS1_1SHF-1_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.37
Foldx random average score for Saccharomyces cerevisiae: 20.076

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1524385
Proteins after disorder filtering: 4289
 Total fragments: 68378
Proteins after pattern filtering: 2224
 Total fragments: 16313
Proteins after MINT filtering: 23
 Total fragments: 254


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.37

-0.41

0.00

Best peptides

RRRRKRRRRR

0.00

-2.93

-2.52

         
Interactors      
P11710

PLPLTPNSKY

14.94

-7.15

-6.74

KPLPLTPNSK

16.78

-7.20

-6.79

SKPLPLTPNS

18.71

-4.03

-3.62

P36119

TRPTVQPSNQ

14.54

-5.04

-4.63

RPTVQPSNQS

15.66

-7.57

-7.16

P40073

DGYPQQQPSH

17.09

-1.95

-1.54

QFDGYPQQQP

17.53

-4.18

-3.77

P24583

NAPLPPQPRK

13.50

-4.38

-3.97

ERANAPLPPQ

13.51

-6.17

-5.76

LPPQPRKHDK

15.26

-5.80

-5.39

P53947

NPIQDPFTDN

19.75

-5.37

-4.96

P34250

YPKEPPARKS

15.54

-6.99

-6.58

KPAYVPPEDV

15.68

-4.90

-4.49

KKPSNPPSSG

16.13

-4.66

-4.25

P53046

QLSTPPTPKS

15.81

-6.22

-5.81

TPPTPKSAGH

17.85

-7.25

-6.84

NQLSTPPTPK

18.85

-3.97

-3.56

Q12280

TPPLRPQSSS

15.22

-7.19

-6.78

TNVTPPLRPQ

15.23

-5.10

-4.69

PPLRPQSSSK

15.61

-5.95

-5.54

P39732

HPSIAPPSKL

14.02

-7.46

-7.05

RHPSIAPPSK

16.47

-5.26

-4.85

SRSPSVSPVR

17.34

-3.15

-2.74

P40091

NPSHPHHNSR

16.77

-8.48

-8.07

FGMSSPASSP

17.31

-3.01

-2.60

QNPSHPHHNS

19.06

-1.85

-1.44

P40450

KLPQLPPPPP

13.32

-7.39

-6.98

LPQLPPPPPP

13.47

-9.45

-9.04

SPKLFPRLSS

14.34

-7.82

-7.41

P25376

RPSSQPHLGY

14.97

-7.62

-7.21

DRPSSQPHLG

15.86

-7.26

-6.85

P41832

KGETPPPPPL

13.90

-6.23

-5.82

PPPPPPMALF

14.98

-9.17

-8.76

QPPPPPPPPP

15.35

-8.46

-8.05

Q03466

SGSSVPMAPD

17.28

-5.06

-4.65

SVPMAPDTFN

19.94

-6.79

-6.38

P31374

FRKTKPPPPL

12.07

-7.72

-7.31

RKTKPPPPLD

13.44

-8.57

-8.16

KPGTPVFPNL

16.00

-6.42

-6.01

P32917

FPPYSPLLPP

12.98

-7.18

-6.77

LPQHPHRTSS

13.53

-8.83

-8.42

PPYSPLLPPF

15.53

-7.47

-7.06

P40020

KKSRVLPPLP

11.79

-7.34

-6.93

SRVLPPLPFP

12.86

-6.30

-5.89

PPYLSPQNKD

14.85

-6.88

-6.47

P16892

EPEGEPIPPS

17.94

-5.29

-4.88

DPNDEPEGEP

18.55

-5.14

-4.73

Q12114

LKSEPVGTPN

19.02

-4.77

-4.36

SLKSEPVGTP

19.26

-5.74

-5.33

SGHETAPVSP

19.97

-3.23

-2.82

P21268

KPISPPPSLK

12.88

-7.69

-7.28

PLNLSKPISP

16.18

-5.50

-5.09

LNLSKPISPP

16.41

-5.04

-4.63

P53950

NPNGAPLRRY

11.36

-8.80

-8.39

TPPAPLLPLP

15.02

-7.91

-7.50

APSTAPLGST

16.52

-4.76

-4.35

Q12753

LMMIKPKGRP

12.24

-7.00

-6.59

LPDTSPMSSI

15.01

-7.67

-7.26

IPQSPPLSSM

15.29

-7.09

-6.68

P14681

EPEYPPLNLD

15.26

-6.42

-6.01

DPSDEPEYPP

17.52

-5.45

-5.04

 


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