ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-7.PDB
Scoring matrix: FUS1_1PWT-7_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 16.53
Foldx random average score for Saccharomyces cerevisiae: 13.119

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1388319
Proteins after disorder filtering: 4219
 Total fragments: 42387
Proteins after pattern filtering: 1506
 Total fragments: 4101
Proteins after MINT filtering: 15
 Total fragments: 50


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

16.53

-1.59

0.00

Best peptides

MRPRRPRR

0.00

-5.74

-4.15

         
Interactors      
P11710

PLPLTPNS

12.35

-1.20

0.39

PLTPNSKY

13.04

-2.13

-0.54

Q12280

TPPLRPQS

10.29

-3.92

-2.33

PPLRPQSS

12.62

-2.24

-0.65

P36119

RPTVQPSN

11.81

-2.65

-1.06

P40073

YPQQQPSH

12.88

-2.16

-0.57

P24583

PLPPQPRK

10.82

-4.11

-2.52

PPQPRKHD

12.56

-3.36

-1.77

LPPQPRKH

12.95

-4.74

-3.15

P39732

SPSVSPVR

11.57

-2.68

-1.09

P53950

PAPLLPLP

11.62

-4.72

-3.13

NPNGAPLR

12.86

-2.86

-1.27

PLLPLPSL

12.91

-2.35

-0.76

P40450

SPKLFPRL

9.83

-5.97

-4.38

SSPKLFPR

11.90

-2.76

-1.17

SSSPKLFP

12.74

-2.93

-1.34

P32917

YLPQHPHR

10.86

-3.81

-2.22

RFPPYSPL

11.22

-1.89

-0.30

YSPLLPPF

11.29

-3.36

-1.77

P40020

VLPPLPFP

11.18

-4.56

-2.97

PPLPFPLY

12.18

-3.04

-1.45

PPPLTPEK

12.38

-2.38

-0.79

P41832

PPPPMALF

12.12

-3.28

-1.69

APPMMPAS

12.32

-2.69

-1.10

PPPPLPSV

12.95

-2.02

-0.43

P53046

STPPTPKS

13.11

-1.96

-0.37

P53947

FNPIQDPF

11.91

-3.65

-2.06

ASPFNPIQ

12.81

-2.25

-0.66

Q12753

NSPRMPKT

7.86

-3.58

-1.99

MIKPKGRP

10.90

-6.11

-4.52

INSPRMPK

11.62

-4.94

-3.35

P31374

SPERPSFR

8.14

-4.62

-3.03

EQPRLPST

8.67

-2.52

-0.93

ISPERPSF

10.09

-3.20

-1.61

 


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