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Matrix information:
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ADAN-name: FUS1_1PWT-27.PDB
Scoring matrix: FUS1_1PWT-27_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 16.49
Foldx random average score for Saccharomyces cerevisiae: 16.081 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1522960
Proteins after disorder filtering: 4545
Total fragments: 98296
Proteins after pattern filtering: 2311
Total fragments: 19612
Proteins after MINT filtering: 24
Total fragments: 288
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAAA |
16.49
|
-4.17 |
0.00 |
| Best peptides |
RRKRRHRRR |
0.00
|
-3.76 |
0.41 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNS |
13.68
|
-3.48 |
0.69 |
|
PLTPNSKYN |
14.06
|
-4.73 |
-0.56 |
|
SKPLPLTPN |
15.84
|
-3.74 |
0.43 |
| P36119 |
TTRPTVQPS |
12.81
|
-4.66 |
-0.49 |
|
STTRPTVQP |
14.66
|
-4.28 |
-0.11 |
| P40073 |
DGYPQQQPS |
12.82
|
-4.50 |
-0.33 |
|
YPQQQPSHT |
14.35
|
-6.13 |
-1.96 |
|
FDGYPQQQP |
14.96
|
-4.74 |
-0.57 |
| P24583 |
PLPPQPRKH |
10.05
|
-7.66 |
-3.49 |
|
RANAPLPPQ |
11.29
|
-7.21 |
-3.04 |
|
APLPPQPRK |
11.56
|
-5.89 |
-1.72 |
| P53947 |
PFNPIQDPF |
13.41
|
-4.23 |
-0.06 |
|
SPFNPIQDP |
14.22
|
-4.38 |
-0.21 |
| P34250 |
PKEPPARKS |
9.55
|
-6.62 |
-2.45 |
|
YPKEPPARK |
9.75
|
-7.06 |
-2.89 |
|
HSKKPSNPP |
10.07
|
-5.69 |
-1.52 |
| P53046 |
LSTPPTPKS |
13.02
|
-5.16 |
-0.99 |
|
STPPTPKSA |
14.08
|
-4.28 |
-0.11 |
|
PPTPKSAGH |
14.89
|
-4.99 |
-0.82 |
| Q12280 |
NVTPPLRPQ |
9.25
|
-7.85 |
-3.68 |
|
YSGSPSKPG |
10.65
|
-7.23 |
-3.06 |
|
INTAPASPE |
13.11
|
-5.78 |
-1.61 |
| P39732 |
RHPSIAPPS |
12.16
|
-5.31 |
-1.14 |
|
PSVSPVRTT |
12.26
|
-6.47 |
-2.30 |
|
TRHPSIAPP |
12.27
|
-4.93 |
-0.76 |
| P40091 |
NPSHPHHNS |
12.09
|
-5.01 |
-0.84 |
|
PSHPHHNSR |
13.23
|
-5.12 |
-0.95 |
|
MSSPASSPV |
13.32
|
-4.88 |
-0.71 |
| P40450 |
LPPPPPPPP |
11.20
|
-6.67 |
-2.50 |
|
VPPPPPPPP |
11.77
|
-6.88 |
-2.71 |
|
QLPPPPPPP |
11.86
|
-5.75 |
-1.58 |
| P25376 |
RPSSQPHLG |
11.96
|
-4.74 |
-0.57 |
|
NDRPSSQPH |
12.15
|
-5.04 |
-0.87 |
|
SNDRPSSQP |
13.88
|
-4.11 |
0.06 |
| P41832 |
PPAPPMMPA |
11.19
|
-6.86 |
-2.69 |
|
QPPPPPPPP |
11.49
|
-5.96 |
-1.79 |
|
PPPPPPPPM |
11.78
|
-6.14 |
-1.97 |
| Q03466 |
VPMAPDTFN |
13.91
|
-5.04 |
-0.87 |
|
SSVPMAPDT |
14.28
|
-3.87 |
0.30 |
|
SGSSVPMAP |
15.00
|
-4.42 |
-0.25 |
| P31374 |
RKTKPPPPL |
8.99
|
-6.23 |
-2.06 |
|
SPERPSFRQ |
10.73
|
-6.30 |
-2.13 |
|
NNISPERPS |
10.79
|
-6.81 |
-2.64 |
| P32917 |
LPQHPHRTS |
9.17
|
-7.36 |
-3.19 |
|
RFPPYSPLL |
10.74
|
-4.78 |
-0.61 |
|
SRFPPYSPL |
11.15
|
-4.54 |
-0.37 |
| P40020 |
RVLPPLPFP |
10.05
|
-6.50 |
-2.33 |
|
FDRPPPLTP |
10.29
|
-7.45 |
-3.28 |
|
DRPPPLTPE |
11.56
|
-4.50 |
-0.33 |
| P16892 |
EGEPIPPSF |
13.34
|
-3.65 |
0.52 |
|
YHDPNDEPE |
13.72
|
-3.32 |
0.85 |
|
NDEPEGEPI |
14.19
|
-3.00 |
1.17 |
| P40210 |
PTEPQTNDS |
15.79
|
-3.09 |
1.08 |
| Q12114 |
KSEPVGTPN |
12.34
|
-3.95 |
0.22 |
|
HETAPVSPV |
12.47
|
-6.11 |
-1.94 |
|
LKSEPVGTP |
15.53
|
-4.05 |
0.12 |
| P21268 |
LSKPISPPP |
11.38
|
-5.16 |
-0.99 |
|
NLSKPISPP |
12.68
|
-3.71 |
0.46 |
|
PISPPPSLK |
13.06
|
-5.14 |
-0.97 |
| P53950 |
PNGAPLRRY |
8.64
|
-9.40 |
-5.23 |
|
VAPNPSIPS |
12.97
|
-6.51 |
-2.34 |
|
TPPAPLLPL |
13.12
|
-6.33 |
-2.16 |
| Q12753 |
MIKPKGRPS |
8.60
|
-8.15 |
-3.98 |
|
HRYPPMAPT |
8.84
|
-7.49 |
-3.32 |
|
MMIKPKGRP |
9.64
|
-9.44 |
-5.27 |
| P14681 |
YHDPSDEPE |
13.64
|
-3.65 |
0.52 |
|
PEYPPLNLD |
13.76
|
-5.06 |
-0.89 |
|
SDEPEYPPL |
14.18
|
-2.26 |
1.91 |
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