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Matrix information:
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ADAN-name: FUS1_1PWT-23.PDB
Scoring matrix: FUS1_1PWT-23_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 14.98
Foldx random average score for Saccharomyces cerevisiae: 13.359 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3221900
Proteins after random average filtering: 7179
Total fragments: 1516872
Proteins after disorder filtering: 4845
Total fragments: 87753
Proteins after pattern filtering: 2046
Total fragments: 8081
Proteins after MINT filtering: 23
Total fragments: 84
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
14.98
|
-0.54 |
0.00 |
| Best peptides |
RPRRYWR |
0.00
|
-1.61 |
-1.08 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNS |
8.91
|
-3.23 |
-2.69 |
| P36119 |
TRPTVQP |
10.23
|
-1.76 |
-1.23 |
|
RPTVQPS |
11.82
|
-2.88 |
-2.34 |
|
PTVQPSN |
12.86
|
-1.45 |
-0.91 |
| P40073 |
YPQQQPS |
11.97
|
-1.47 |
-0.93 |
|
PQQQPSH |
12.19
|
-1.74 |
-1.21 |
|
GYPQQQP |
12.62
|
-1.82 |
-1.29 |
| P24583 |
LPPQPRK |
10.39
|
-2.87 |
-2.34 |
| P53947 |
ASPFNPI |
12.08
|
-1.67 |
-1.13 |
|
NPIQDPF |
12.70
|
-1.09 |
-0.56 |
| P34250 |
KPAYVPP |
10.16
|
-3.27 |
-2.73 |
|
YPKEPPA |
10.27
|
-2.41 |
-1.88 |
|
LYPKEPP |
11.44
|
-3.17 |
-2.63 |
| P53046 |
TPPTPKS |
9.25
|
-1.43 |
-0.89 |
| Q12280 |
PPLRPQS |
5.57
|
-2.16 |
-1.63 |
|
ASPEEPK |
12.64
|
-1.67 |
-1.13 |
|
SPEEPKE |
12.83
|
-1.36 |
-0.83 |
| P39732 |
RHPSIAP |
11.80
|
-2.52 |
-1.98 |
|
RSPSVSP |
11.82
|
-2.18 |
-1.65 |
|
PSVSPVR |
12.69
|
-0.74 |
-0.20 |
| P40091 |
QNPSHPH |
12.85
|
-1.67 |
-1.13 |
|
WDPSSPS |
12.97
|
-1.06 |
-0.53 |
|
NPSHPHH |
13.13
|
-2.03 |
-1.49 |
| P40450 |
PKLFPRL |
8.07
|
-4.41 |
-3.88 |
|
KLPQLPP |
11.42
|
-2.52 |
-1.98 |
|
SPKLFPR |
12.06
|
-3.35 |
-2.81 |
| P25376 |
RPSSQPH |
11.09
|
-2.09 |
-1.55 |
|
PSSQPHL |
12.87
|
-1.37 |
-0.84 |
| P41832 |
PPMMPAS |
10.66
|
-3.57 |
-3.03 |
|
APPMMPA |
12.18
|
-1.94 |
-1.40 |
|
PPPVPAK |
12.87
|
-2.84 |
-2.30 |
| P31374 |
EQPRLPS |
8.03
|
-0.18 |
0.36 |
|
SPERPSF |
9.13
|
-1.51 |
-0.97 |
|
KPGTPVF |
10.29
|
-1.96 |
-1.42 |
| P32917 |
LPQHPHR |
10.77
|
-2.97 |
-2.44 |
|
FPPYSPL |
10.86
|
-3.04 |
-2.50 |
|
YLPQHPH |
11.66
|
-2.66 |
-2.13 |
| P40020 |
PPLTPEK |
8.87
|
-2.44 |
-1.90 |
|
EEPTSPT |
10.59
|
-0.20 |
0.34 |
|
PLPFPLY |
10.81
|
-2.74 |
-2.21 |
| P16892 |
PEGEPIP |
13.20
|
-2.40 |
-1.86 |
| P40210 |
VDPTEPQ |
12.23
|
-0.90 |
-0.36 |
| Q12114 |
PVGTPNI |
11.98
|
-0.96 |
-0.42 |
| P21268 |
KPISPPP |
11.67
|
-1.71 |
-1.17 |
| P53950 |
APSTAPL |
11.52
|
-1.05 |
-0.52 |
|
PNGAPLR |
12.56
|
-1.86 |
-1.33 |
|
APLLPLP |
12.69
|
-4.38 |
-3.84 |
| Q12753 |
PKGRPST |
8.14
|
-1.23 |
-0.69 |
|
NSPRMPK |
8.87
|
-3.03 |
-2.49 |
|
SPRMPKT |
9.11
|
-2.92 |
-2.38 |
| P14681 |
EPEYPPL |
11.20
|
-1.60 |
-1.06 |
|
DEPEYPP |
12.94
|
-1.49 |
-0.95 |
|
PSDEPEY |
12.99
|
-1.69 |
-1.15 |
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