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Matrix information:
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ADAN-name: FUS1_1PWT-21.PDB
Scoring matrix: FUS1_1PWT-21_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.18
Foldx random average score for Saccharomyces cerevisiae: 16.899 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3200363
Proteins after random average filtering: 7179
Total fragments: 1954547
Proteins after disorder filtering: 4455
Total fragments: 78602
Proteins after pattern filtering: 1819
Total fragments: 4996
Proteins after MINT filtering: 21
Total fragments: 72
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAGGAAAA |
19.18
|
-1.10 |
0.00 |
| Best peptides |
EWRFGRPTWH |
0.00
|
0.14 |
1.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNSK |
13.41
|
-4.45 |
-3.35 |
|
PLPLTPNSKY |
14.95
|
-5.84 |
-4.74 |
| Q12280 |
PLRPQSSSKI |
10.74
|
-5.62 |
-4.52 |
|
PSKPGNNNSY |
13.59
|
-3.43 |
-2.33 |
|
VTPPLRPQSS |
15.39
|
-3.83 |
-2.73 |
| P36119 |
TRPTVQPSNQ |
14.68
|
-3.50 |
-2.40 |
|
RPTVQPSNQS |
15.73
|
-3.94 |
-2.84 |
| P40073 |
GYPQQQPSHT |
13.11
|
-4.11 |
-3.01 |
| P24583 |
PPQPRKHDKT |
14.14
|
-2.59 |
-1.49 |
|
APLPPQPRKH |
14.22
|
-4.99 |
-3.89 |
|
PLPPQPRKHD |
15.72
|
-4.50 |
-3.40 |
| P39732 |
HPSIAPPSKL |
13.12
|
-5.08 |
-3.98 |
|
RSPSVSPVRT |
14.95
|
-4.00 |
-2.90 |
|
SPSVSPVRTT |
16.11
|
-3.15 |
-2.05 |
| P40091 |
TWDPSSPSSV |
13.80
|
-4.08 |
-2.98 |
|
SQNPSHPHHN |
14.17
|
-3.20 |
-2.10 |
|
SPASSPVTWD |
15.38
|
-1.90 |
-0.80 |
| P40450 |
SSPKLFPRLS |
13.49
|
-3.74 |
-2.64 |
|
PPLPESLSMN |
14.44
|
-4.18 |
-3.08 |
|
PPPPLPQSLL |
15.15
|
-5.25 |
-4.15 |
| P32917 |
DYLPQHPHRT |
10.75
|
-3.64 |
-2.54 |
|
PQHPHRTSSL |
14.18
|
-3.22 |
-2.12 |
|
YLPQHPHRTS |
16.19
|
-3.64 |
-2.54 |
| P25376 |
DRPSSQPHLG |
15.30
|
-3.97 |
-2.87 |
| P40020 |
SEEPTSPTRQ |
9.96
|
-5.02 |
-3.92 |
|
TSAPSIPVEH |
12.67
|
-3.95 |
-2.85 |
|
EEPTSPTRQV |
13.77
|
-2.96 |
-1.86 |
| P41832 |
PPLPSVLSSS |
16.26
|
-2.34 |
-1.24 |
| Q12114 |
SEPVGTPNIE |
14.25
|
-4.78 |
-3.68 |
| Q03466 |
PMAPDTFNVK |
13.00
|
-5.04 |
-3.94 |
|
SVPMAPDTFN |
13.56
|
-5.02 |
-3.92 |
| P53046 |
PPTPKSAGHT |
15.87
|
-4.12 |
-3.02 |
| P31374 |
NISPERPSFR |
9.29
|
-6.13 |
-5.03 |
|
VFPNLDPTHS |
13.02
|
-5.02 |
-3.92 |
|
PPSPDQENHI |
14.68
|
-4.28 |
-3.18 |
| P53947 |
NPIQDPFTDN |
15.67
|
-1.53 |
-0.43 |
|
FNPIQDPFTD |
16.66
|
-4.59 |
-3.49 |
| Q12753 |
IKPKGRPSTT |
12.03
|
-4.61 |
-3.51 |
|
PRMPKTGSRQ |
12.84
|
-4.48 |
-3.38 |
|
RYPPMAPTTV |
12.93
|
-3.74 |
-2.64 |
| P34250 |
SSNPDLPTAL |
12.70
|
-4.26 |
-3.16 |
|
LYPKEPPARK |
12.88
|
-5.12 |
-4.02 |
| P53950 |
PSIPSASTST |
12.65
|
-3.05 |
-1.95 |
|
SNPNGAPLRR |
14.84
|
-4.63 |
-3.53 |
|
NPNGAPLRRY |
15.95
|
-2.59 |
-1.49 |
| P40210 |
EVDPTEPQTN |
15.39
|
-5.10 |
-4.00 |
|
VDPTEPQTND |
16.38
|
-3.41 |
-2.31 |
|
PTEPQTNDSE |
16.74
|
-0.41 |
0.69 |
|
