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Matrix information:
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ADAN-name: FUS1_1PWT-18.PDB
Scoring matrix: FUS1_1PWT-18_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 17.43
Foldx random average score for Saccharomyces cerevisiae: 16.935 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3200363
Proteins after random average filtering: 7179
Total fragments: 1455208
Proteins after disorder filtering: 4513
Total fragments: 80714
Proteins after pattern filtering: 2009
Total fragments: 8844
Proteins after MINT filtering: 20
Total fragments: 114
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAAA |
17.43
|
4.09 |
0.00 |
| Best peptides |
RRPFRSRWKR |
0.00
|
-1.37 |
-5.46 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPNSKY |
9.68
|
-3.12 |
-7.21 |
|
LPLTPNSKYN |
13.39
|
-5.31 |
-9.40 |
|
KPLPLTPNSK |
15.11
|
-0.24 |
-4.33 |
| Q12280 |
TPPLRPQSSS |
12.84
|
-2.05 |
-6.14 |
|
PLRPQSSSKI |
13.32
|
0.41 |
-3.68 |
|
SPSKPGNNNS |
13.74
|
-1.10 |
-5.19 |
| P36119 |
RPTVQPSNQS |
14.08
|
-3.30 |
-7.39 |
|
TRPTVQPSNQ |
15.48
|
-2.72 |
-6.81 |
|
PTVQPSNQST |
15.69
|
0.84 |
-3.25 |
| P40073 |
GYPQQQPSHT |
16.93
|
-0.96 |
-5.05 |
| P24583 |
APLPPQPRKH |
12.93
|
-1.36 |
-5.45 |
|
NAPLPPQPRK |
14.34
|
-4.03 |
-8.12 |
|
PPQPRKHDKT |
15.05
|
-0.73 |
-4.82 |
| P39732 |
HPSIAPPSKL |
9.98
|
-2.13 |
-6.22 |
|
RSPSVSPVRT |
12.05
|
-0.92 |
-5.01 |
|
SSPSPSPTSS |
15.09
|
2.19 |
-1.90 |
| P21268 |
PISPPPSLKK |
14.05
|
-0.88 |
-4.97 |
|
SKPISPPPSL |
14.79
|
-2.54 |
-6.63 |
|
KPISPPPSLK |
16.78
|
-0.54 |
-4.63 |
| P40091 |
DPSSPSSVGS |
11.59
|
-1.93 |
-6.02 |
|
NPSHPHHNSR |
13.42
|
-1.67 |
-5.76 |
|
SSPASSPVTW |
16.41
|
4.95 |
0.86 |
| P40450 |
SPKLFPRLSS |
11.17
|
-2.80 |
-6.89 |
|
PPPLPDLFKT |
11.31
|
-1.91 |
-6.00 |
|
PPPLPESLSM |
13.72
|
-3.07 |
-7.16 |
| P32917 |
YSPLLPPFGL |
10.41
|
-2.25 |
-6.34 |
|
LPQHPHRTSS |
12.25
|
-2.87 |
-6.96 |
|
YLPQHPHRTS |
16.65
|
2.50 |
-1.59 |
| P25376 |
RPSSQPHLGY |
8.44
|
-3.03 |
-7.12 |
|
SNDRPSSQPH |
16.54
|
-2.40 |
-6.49 |
| P40020 |
PPYLSPQNKD |
10.69
|
-2.31 |
-6.40 |
|
LPPLPFPLYD |
12.00
|
-4.81 |
-8.90 |
|
LPPYLSPQNK |
12.15
|
-0.92 |
-5.01 |
| P41832 |
PPPLPSVLSS |
11.98
|
-2.23 |
-6.32 |
|
PPPPMALFGK |
14.05
|
-1.46 |
-5.55 |
|
PPPPPVPAKL |
14.26
|
-0.21 |
-4.30 |
| P16892 |
HDPNDEPEGE |
16.60
|
0.96 |
-3.13 |
| Q03466 |
SVPMAPDTFN |
16.57
|
-2.51 |
-6.60 |
| P53046 |
TPPTPKSAGH |
11.53
|
-2.05 |
-6.14 |
|
QLSTPPTPKS |
13.54
|
-0.81 |
-4.90 |
|
LSTPPTPKSA |
16.45
|
-1.85 |
-5.94 |
| P31374 |
TPDDLPPLKE |
12.79
|
0.07 |
-4.02 |
|
ISPERPSFRQ |
13.22
|
-1.12 |
-5.21 |
|
QPRLPSTASS |
13.41
|
-3.12 |
-7.21 |
| Q12753 |
NSPRMPKTGS |
12.81
|
-0.91 |
-5.00 |
|
LPDTSPMSSI |
13.32
|
-1.56 |
-5.65 |
|
SPRMPKTGSR |
13.62
|
-2.82 |
-6.91 |
| P34250 |
KPSNPPSSGN |
11.40
|
-2.41 |
-6.50 |
|
LYPKEPPARK |
11.97
|
-1.36 |
-5.45 |
|
YPKEPPARKS |
12.87
|
-0.59 |
-4.68 |
| P53950 |
SNPNGAPLRR |
14.42
|
1.84 |
-2.25 |
|
TAPSTAPLGS |
14.70
|
0.56 |
-3.53 |
|
PNGAPLRRYS |
15.11
|
2.65 |
-1.44 |
|
