ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-15.PDB
Scoring matrix: FUS1_1PWT-15_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.86
Foldx random average score for Saccharomyces cerevisiae: 12.160

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1431775
Proteins after disorder filtering: 4229
 Total fragments: 45731
Proteins after pattern filtering: 1808
 Total fragments: 6091
Proteins after MINT filtering: 18
 Total fragments: 71


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.86

-0.20

0.00

Best peptides

HWFFIMKDW

0.00

-2.56

-2.36

         
Interactors      
P11710

LPLTPNSKY

10.30

-3.50

-3.30

Q12280

NINTAPASP

10.97

-2.80

-2.60

NVTPPLRPQ

11.92

-2.68

-2.48

P36119

RPTVQPSNQ

8.23

-3.72

-3.52

P40073

YPQQQPSHT

11.05

-2.05

-1.85

P24583

PPQPRKHDK

11.22

-1.44

-1.24

P39732

HPSIAPPSK

6.15

-5.55

-5.35

SPSVSPVRT

11.26

-3.31

-3.11

RSPSVSPVR

11.51

0.08

0.28

P21268

KPISPPPSL

11.39

-2.78

-2.58

SKPISPPPS

11.70

-3.19

-2.99

PISPPPSLK

12.15

-3.32

-3.12

P53950

NPSIPSAST

10.06

-1.99

-1.79

NPNGAPLRR

11.48

-1.31

-1.11

P40450

PKLFPRLSS

9.03

-2.22

-2.02

P32917

FPPYSPLLP

8.59

-2.68

-2.48

YLPQHPHRT

10.64

-2.87

-2.67

QSRFPPYSP

11.15

-2.59

-2.39

P40020

LTPESPLNR

9.41

-1.06

-0.86

PLPFPLYDE

9.50

-2.33

-2.13

RPPPLTPEK

10.27

-2.35

-2.15

P41832

VIPPAPPMM

11.86

-2.35

-2.15

Q12114

HETAPVSPV

11.41

-1.49

-1.29

LKSEPVGTP

11.42

-1.81

-1.61

P53947

FNPIQDPFT

8.84

-1.63

-1.43

SPFNPIQDP

11.45

-2.30

-2.10

ASPFNPIQD

12.05

-0.37

-0.17

P34250

YPKEPPARK

9.01

-3.82

-3.62

KPAYVPPED

9.83

-1.42

-1.22

LYPKEPPAR

10.93

-2.05

-1.85

P14681

EPEYPPLNL

10.06

-2.64

-2.44

Q12753

HRYPPMAPT

9.32

-4.53

-4.33

INSPRMPKT

10.06

-1.71

-1.51

IKPKGRPST

10.29

-0.36

-0.16

P31374

ISPERPSFR

10.12

-0.63

-0.43

NISPERPSF

10.26

-0.96

-0.76

TPVFPNLDP

10.30

-4.61

-4.41

 


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