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Matrix information:
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ADAN-name: FUS1_1PWT-13.PDB
Scoring matrix: FUS1_1PWT-13_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.24
Foldx random average score for Saccharomyces cerevisiae: 11.411 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1293436
Proteins after disorder filtering: 4353
Total fragments: 57187
Proteins after pattern filtering: 1956
Total fragments: 8870
Proteins after MINT filtering: 21
Total fragments: 121
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
15.24
|
2.63 |
0.00 |
| Best peptides |
RKRRHPKR |
0.00
|
-1.82 |
-4.45 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKY |
9.15
|
-1.76 |
-4.39 |
|
SKPLPLTP |
9.78
|
-1.78 |
-4.41 |
|
KPLPLTPN |
10.45
|
-1.15 |
-3.78 |
| P36119 |
RPTVQPSN |
8.45
|
-2.68 |
-5.31 |
| Q12280 |
TPPLRPQS |
8.94
|
-2.77 |
-5.40 |
|
NVTPPLRP |
10.22
|
-1.19 |
-3.82 |
|
YSGSPSKP |
10.30
|
-0.27 |
-2.90 |
| P40073 |
YPQQQPSH |
10.77
|
-1.04 |
-3.67 |
| P39732 |
HPSIAPPS |
8.90
|
-2.98 |
-5.61 |
|
SPSVSPVR |
9.62
|
-1.71 |
-4.34 |
|
RHPSIAPP |
10.50
|
-2.00 |
-4.63 |
| P24583 |
LPPQPRKH |
7.71
|
-0.50 |
-3.13 |
|
PLPPQPRK |
10.13
|
-2.53 |
-5.16 |
|
NAPLPPQP |
10.37
|
-2.07 |
-4.70 |
| P21268 |
SKPISPPP |
9.27
|
-0.45 |
-3.08 |
|
KPISPPPS |
10.43
|
-0.35 |
-2.98 |
|
NLSKPISP |
11.29
|
-2.05 |
-4.68 |
| P40091 |
QNPSHPHH |
8.90
|
-2.13 |
-4.76 |
|
NPSHPHHN |
11.26
|
-1.32 |
-3.95 |
| P40450 |
SPKLFPRL |
8.20
|
-3.68 |
-6.31 |
|
KLPQLPPP |
8.68
|
-1.64 |
-4.27 |
|
PKLFPRLS |
10.11
|
-3.48 |
-6.11 |
| P32917 |
YLPQHPHR |
6.65
|
-4.26 |
-6.89 |
|
RFPPYSPL |
7.40
|
-1.01 |
-3.64 |
|
SPLLPPFG |
9.58
|
-1.53 |
-4.16 |
| P25376 |
RPSSQPHL |
8.46
|
-2.27 |
-4.90 |
| P40020 |
RPPPLTPE |
8.71
|
-1.89 |
-4.52 |
|
RVLPPLPF |
8.79
|
-2.86 |
-5.49 |
|
VLPPLPFP |
9.16
|
-2.61 |
-5.24 |
| P41832 |
PPPVPAKL |
8.76
|
-0.99 |
-3.62 |
|
IPPAPPMM |
9.44
|
-2.12 |
-4.75 |
|
PPPPPPMA |
10.25
|
-2.32 |
-4.95 |
| P16892 |
GEPIPPSF |
10.78
|
-0.14 |
-2.77 |
|
YHDPNDEP |
11.02
|
-1.27 |
-3.90 |
| P53947 |
FNPIQDPF |
9.16
|
-0.60 |
-3.23 |
|
SPFNPIQD |
11.17
|
-0.05 |
-2.68 |
| P34250 |
KKPSNPPS |
8.47
|
-1.20 |
-3.83 |
|
PKEPPARK |
9.36
|
-0.91 |
-3.54 |
|
YPKEPPAR |
9.50
|
-1.36 |
-3.99 |
| Q12114 |
HETAPVSP |
10.99
|
-0.38 |
-3.01 |
| Q12753 |
MIKPKGRP |
7.52
|
-3.58 |
-6.21 |
|
NSPRMPKT |
8.32
|
-0.41 |
-3.04 |
|
HRYPPMAP |
8.63
|
-1.88 |
-4.51 |
| P31374 |
RKTKPPPP |
6.65
|
-3.45 |
-6.08 |
|
SPERPSFR |
7.83
|
-0.91 |
-3.54 |
|
KPGTPVFP |
9.07
|
-2.00 |
-4.63 |
| P14681 |
EPEYPPLN |
11.20
|
-1.78 |
-4.41 |
|
DEPEYPPL |
11.34
|
0.18 |
-2.45 |
| P53950 |
PNGAPLRR |
10.47
|
-0.44 |
-3.07 |
|
NPSIPSAS |
10.76
|
-1.83 |
-4.46 |
|
PAPLLPLP |
11.14
|
-2.52 |
-5.15 |
|
