ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-11.PDB
Scoring matrix: FUS1_1PWT-11_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.92
Foldx random average score for Saccharomyces cerevisiae: 9.811

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1466419
Proteins after disorder filtering: 4768
 Total fragments: 89853
Proteins after pattern filtering: 1968
 Total fragments: 7058
Proteins after MINT filtering: 20
 Total fragments: 81


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.92

-0.38

0.00

Best peptides

RRPMRRQ

0.00

-1.22

-0.84

         
Interactors      
P11710

KPLPLTP

8.09

-3.15

-2.77

Q12280

TPPLRPQ

6.10

-2.44

-2.06

GSPSKPG

9.20

-0.80

-0.42

VTPPLRP

9.47

-3.06

-2.68

P36119

TRPTVQP

8.66

-1.12

-0.74

RPTVQPS

8.86

-2.24

-1.86

P24583

PPQPRKH

7.50

-2.92

-2.54

ANAPLPP

9.07

-2.85

-2.47

P39732

RHPSIAP

6.02

-1.45

-1.07

RSPSVSP

7.50

-0.81

-0.43

HPSIAPP

9.21

-4.19

-3.81

P21268

SKPISPP

7.64

-2.73

-2.35

KPISPPP

8.02

-2.53

-2.15

P40091

QNPSHPH

3.83

-2.70

-2.32

SPASSPV

9.14

0.50

0.88

WDPSSPS

9.58

0.93

1.31

P40450

PPPPLPQ

6.84

-2.42

-2.04

SPKLFPR

7.18

-3.07

-2.69

KLPQLPP

7.84

-4.77

-4.39

P32917

FPPYSPL

7.20

-1.75

-1.37

IPPKVAP

7.34

-2.77

-2.39

RFPPYSP

8.10

-3.62

-3.24

P25376

RPSSQPH

6.01

-1.35

-0.97

DRPSSQP

7.99

-0.67

-0.29

P40020

LPPYLSP

7.15

-4.59

-4.21

RPPPLTP

7.59

-3.46

-3.08

NPHSIPF

8.13

-1.49

-1.11

P41832

APPMMPA

7.71

-3.70

-3.32

IPPAPPM

7.92

-2.70

-2.32

PPPPMAL

9.31

-1.96

-1.58

P53947

ASPFNPI

7.60

-2.36

-1.98

FNPIQDP

9.33

-2.66

-2.28

P34250

KKPSNPP

4.29

-3.14

-2.76

KPAYVPP

6.27

-2.64

-2.26

SNPDLPT

7.53

-1.54

-1.16

P14681

EPEYPPL

9.53

-3.37

-2.99

P31374

ISPERPS

7.18

-1.35

-0.97

TPPSPDQ

7.84

-0.54

-0.16

GTPVFPN

8.63

-3.22

-2.84

Q12753

IKPKGRP

7.21

-3.35

-2.97

LPDTSPM

7.21

-1.96

-1.58

KPKGRPS

7.27

-1.37

-0.99

Q03466

SVPMAPD

9.21

-2.04

-1.66

P53950

PNPSIPS

6.93

-1.13

-0.75

APSTAPL

9.19

-1.45

-1.07

P40210

VDPTEPQ

9.27

0.59

0.97

 


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