ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-9.PDB
Scoring matrix: FUS1_1OV32-9_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.59
Foldx random average score for Saccharomyces cerevisiae: 13.509

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1305936
Proteins after disorder filtering: 4170
 Total fragments: 43289
Proteins after pattern filtering: 1813
 Total fragments: 6449
Proteins after MINT filtering: 21
 Total fragments: 91


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.59

-0.96

0.00

Best peptides

RRRRIPRF

0.00

-6.00

-5.04

         
Interactors      
P11710

SKPLPLTP

12.02

-3.51

-2.55

PLPLTPNS

12.68

-3.70

-2.74

Q12280

PPLRPQSS

11.56

-5.30

-4.34

TPPLRPQS

12.14

-3.42

-2.46

NVTPPLRP

12.23

-3.67

-2.71

P36119

RPTVQPSN

12.56

-5.81

-4.85

TRPTVQPS

12.96

-3.56

-2.60

P40073

PQQQPSHT

13.48

-3.65

-2.69

P24583

PLPPQPRK

11.46

-4.06

-3.10

LPPQPRKH

11.54

-5.06

-4.10

NAPLPPQP

12.91

-4.13

-3.17

P39732

PSVSPVRT

12.81

-2.82

-1.86

HPSIAPPS

12.89

-3.81

-2.85

RHPSIAPP

13.06

-3.86

-2.90

P21268

SKPISPPP

11.81

-2.94

-1.98

KPISPPPS

13.14

-4.14

-3.18

P40091

NPSHPHHN

12.47

-3.70

-2.74

P40450

SPKLFPRL

8.09

-4.39

-3.43

PPPLPDLF

9.58

-6.42

-5.46

PKLFPRLS

10.82

-4.98

-4.02

P32917

LPQHPHRT

9.65

-4.64

-3.68

IPPKVAPF

10.47

-2.64

-1.68

SPLLPPFG

10.88

-4.15

-3.19

P25376

RPSSQPHL

11.93

-1.90

-0.94

P40020

SRVLPPLP

10.16

-6.14

-5.18

LPPLPFPL

10.61

-5.15

-4.19

RVLPPLPF

11.08

-3.37

-2.41

P41832

PPPVPAKL

11.27

-5.47

-4.51

IPPAPPMM

11.67

-5.28

-4.32

PPPLPSVL

11.82

-4.38

-3.42

P16892

GEPIPPSF

10.87

-5.22

-4.26

P53947

FNPIQDPF

11.43

-4.94

-3.98

ASPFNPIQ

13.49

-2.81

-1.85

P34250

PKEPPARK

9.96

-4.40

-3.44

LYPKEPPA

11.92

-2.18

-1.22

KPAYVPPE

12.33

-3.72

-2.76

P14681

EPEYPPLN

13.00

-4.56

-3.60

P31374

SPERPSFR

8.44

-5.36

-4.40

RKTKPPPP

8.96

-5.68

-4.72

EQPRLPST

10.72

-2.18

-1.22

Q12753

PKGRPSTT

9.66

-5.61

-4.65

NSPRMPKT

9.72

-4.25

-3.29

MIKPKGRP

10.93

-6.13

-5.17

Q03466

SVPMAPDT

13.11

-3.06

-2.10

P53950

PNGAPLRR

12.22

-4.28

-3.32

APLLPLPS

12.43

-3.62

-2.66

NPSIPSAS

12.44

-4.19

-3.23

 


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