ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-29.PDB
Scoring matrix: FUS1_1OV32-29_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.3
Foldx random average score for Saccharomyces cerevisiae: 13.657

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1309574
Proteins after disorder filtering: 4258
 Total fragments: 65124
Proteins after pattern filtering: 2189
 Total fragments: 15687
Proteins after MINT filtering: 23
 Total fragments: 211


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.30

2.28

0.00

Best peptides

KLFKFMPMRF

0.00

-6.89

-9.17

         
Interactors      
P11710

PLPLTPNSKY

10.24

-5.52

-7.80

PLTPNSKYNG

11.17

-2.60

-4.88

SKPLPLTPNS

12.21

-4.16

-6.44

P36119

TRPTVQPSNQ

11.60

-4.39

-6.67

RPTVQPSNQS

12.31

-3.97

-6.25

SSTTRPTVQP

12.93

-3.90

-6.18

P53046

QLSTPPTPKS

10.39

-4.81

-7.09

NQLSTPPTPK

12.13

-7.74

-10.02

P24583

NAPLPPQPRK

9.09

-7.19

-9.47

PLPPQPRKHD

11.05

-4.16

-6.44

APLPPQPRKH

11.18

-4.73

-7.01

P53947

SPFNPIQDPF

12.18

-3.01

-5.29

P34250

LYPKEPPARK

8.39

-6.10

-8.38

YPKEPPARKS

9.97

-6.91

-9.19

EPKPAYVPPE

10.37

-4.65

-6.93

Q03466

SVPMAPDTFN

10.49

-4.27

-6.55

VPMAPDTFNV

13.11

-2.26

-4.54

Q12280

TAPASPEEPK

10.01

-3.09

-5.37

PLRPQSSSKI

10.89

-4.57

-6.85

NINTAPASPE

11.57

-3.96

-6.24

P39732

RSPSVSPVRT

9.93

-5.30

-7.58

TRHPSIAPPS

10.52

-5.43

-7.71

HPSIAPPSKL

11.10

-4.51

-6.79

P40091

PVTWDPSSPS

11.49

-5.44

-7.72

QNPSHPHHNS

11.56

-4.51

-6.79

PSHPHHNSRP

12.69

-4.91

-7.19

P40450

DLVTPPAPPL

9.30

-6.09

-8.37

QLPPPPPPPP

9.40

-5.89

-8.17

AVPPPPPPPP

10.21

-5.42

-7.70

P25376

DRPSSQPHLG

11.35

-6.19

-8.47

NDRPSSQPHL

12.86

-2.78

-5.06

P41832

VIPPAPPMMP

7.96

-7.05

-9.33

IPPAPPMMPA

9.67

-5.62

-7.90

PPPPPPPMAL

10.00

-5.61

-7.89

P31374

FRKTKPPPPL

8.53

-8.34

-10.62

NISPERPSFR

9.41

-4.73

-7.01

ISPERPSFRQ

10.14

-6.15

-8.43

P32917

SRFPPYSPLL

8.45

-5.65

-7.93

YLPQHPHRTS

9.67

-3.92

-6.20

QSRFPPYSPL

11.08

-5.90

-8.18

P40020

NLYLTPESPL

10.03

-5.60

-7.88

YLTPESPLNR

10.25

-3.43

-5.71

PLTPEKNLYL

10.73

-6.40

-8.68

P16892

EPEGEPIPPS

11.71

-3.84

-6.12

TYHDPNDEPE

12.10

-1.71

-3.99

DEPEGEPIPP

13.63

-1.97

-4.25

P40210

HDEVDPTEPQ

12.15

-3.01

-5.29

VDPTEPQTND

12.52

-3.11

-5.39

Q12114

SLKSEPVGTP

11.54

-4.74

-7.02

GHETAPVSPV

12.45

-3.95

-6.23

P21268

SKPISPPPSL

10.45

-5.02

-7.30

KPISPPPSLK

10.84

-4.15

-6.43

NLSKPISPPP

11.04

-4.40

-6.68

P53950

VVAPNPSIPS

9.90

-5.48

-7.76

NPNGAPLRRY

11.31

-5.80

-8.08

TKTAPSTAPL

12.44

-2.03

-4.31

Q12753

MMIKPKGRPS

9.64

-5.85

-8.13

LMMIKPKGRP

9.71

-6.13

-8.41

HRYPPMAPTT

9.74

-5.60

-7.88

P14681

DPSDEPEYPP

12.05

-5.45

-7.73

SDEPEYPPLN

12.47

-1.50

-3.78

DEPEYPPLNL

13.08

-3.80

-6.08

 


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